ASCP Hematology | 250 Questions and Answers with complete solution

Name the locations of active marrow in adults: - sternum, skull, ribs, pelvis, vertebrae Where does hematopoiesis take place during the first 2 months of gestation? - yolk sac Where does the majority of hematopoiesis take place during the 2nd through 7th month of gestation? - spleen When does the bone marrow take over hematopoiesis? - after birth What are the stages in order of the erythrocyte lineage? - (1)rubriblast, (2)prorubricyte, (3)rubricyte, (4)metarubricyte, (5)reticulocyte, (6)erytrocyte What are the stages in order of the granulocyte (neutrophil, eosinophil, basophil) lineage? - (1)myeloblast, (2)promyelocyte, (3)myelocyte, (4)metamyelocyte, (5)band, (6)segmented (7)eos/baso What are the stages in order of the macrophage lineage? - (1)monoblast, (2)promonocyte, (3)monocyte, (4)macrophage What are the stages in order of the platelet lineage? - (1)megakaryoblast, (2)promegakaryocyte, (3)megakaryocyte, (4)platelet What are the stages in order of the lymphocyte lineage? - (1)lymphoblast, (2)prolymphocyte, (3)lymphocyte Which growth factors stimulate the erythrocyte lineage? - GM-CSF, EPO, IL-3 Which growth factors stimulate the granulocyte lineages? - GM-CSF, IL-3Which growth factors stimulate the platelet lineage? - GM-CSF, IL-3, TPO Which growth factors stimulate the lymphocyte lineage? - IL-2, IL-4, IL-6, IL-7 Which protein functions in the transport of Fe? - transferrin What is the major storage form of Fe? - ferritin What is the long-term (H20) insoluble Fe storage form called? - hemosiderin Excess Iron is stored where? What does this cause? - tissues and body organs, hemosiderosis, hemochromatosis