Summary NR 566 Final Exam Study Guide 2023/2024 (Advanced Pharmacology Care Of The Family)

NR 566 Final Exam Study Guide 2023/2024. NR 566 / NR566 Advanced Pharmacology Care Of The Family. Complete the following table to study/prepare for the treatment of STIs/STDs according to National STD curriculum completed in Week 5 of the course. STI/STD First line drug, dose, route, frequency Chlamydia (Among Adolescents and Adults) Doxycycline 100 mg PO bid x7 days During pregnancy: Azithromycin 1 g PO single dose Uncomplicated gonococcal urethritis Ceftriaxone 500 mg IM single dose plus Doxycycline 100 mg PO bid x7 days Bacterial Vaginosis 1.) Metronidazole 500 mg PO bid x7 days 2.) Metronidazole gel 0.75%, one full applicator (5 g) intravaginally once daily x5 days 3.) Clindamycin vaginal cream 2%, one full applicator (5 g) inserted at bedtime x7 days Herpes Simplex Virus (First Clinical Episode) 1.) Acyclovir 400 mg PO tid x7-10 days 2.) Famciclovir 250 mg PO tid x7-10 days 3.) Valacyclovir 1 g PO bid x7-10 days Pelvic Inflammatory Disease (PID) (IM or Oral Regimens) 1.) Ceftriaxone 500 mg IM single dose plus Doxycycline 100 mg PO bid x14 days plus metronidazole 500 mg PO bid x14 days 2.) Cefoxitin 2 mg IM single dose plus probenecid 1 g PO single dose plus Doxycycline 100 mg PO x14 days plus metronidazole 500 mg PO bid x14 days Syphilis (Primary and Secondary) Benzathine PCN G 2.4 million units IM single dose  Doxazosin (non-selective alpha 1 blocker): o Side Effects -  hypotension, dizziness, nasal congestion, somnolence  Dutasteride (5-alpha-reductase inhibitors): o Patient teaching and response to delayed onset of therapeutic effect  May take 1 month to take effect  Adverse effects –  Decreased ejaculate volume and libido  Teratogenic to the male fetus  Terazosin: o How to know it’s working – NR566 Final Study Guide  Relaxes smooth muscles of the bladder neck to improve urinary symptoms  Various routes of administration of estrogen therapy and when each would be used  Oral -> most used  Transdermal -> 4 advantages:  Total dose of estrogen is greatly reduced because liver is bypassed  Less nausea and vomiting  Blood levels of estrogen fluctuate less  Lower risk of DVT, PE, and stroke  Intravaginal:  Used for local effects primarily to treat volvovaginitis and vaginal atrophy  Parenteral -> RARE  Limited to acute emergency control of heavy uterine bleeding  When is it safe and not safe to prescribe progesterone (AKA: progestin) o Therapeutic uses -  Counteract endometrial hypoplasia caused by unopposed estrogen during hormone therapy  Management of dysfunctional uterine bleeding  Amenorrhea and endometriosis  Supportive for pregnancy in women with corpus luteum deficiency  In vitro fertilization  Prevent prematurity in women at high risk for pre-term birth  Necessary to reduce the risk of endometrial cancer