NR 507 Autoimmunity (Test questions, 100% verified)

Sjorgren's Syndrome correct answers _____ is associated with autoantibodies and auto-reactive T-cells against apoptotic cells Antinuclear Antibody (ANA) correct answers The ________ test is positive in 90% of patients diagnosed with Systemic Lupus Erythematosus (SLE). Autoimmunity correct answers _____ is an alteration in the ability of the body to tolerate its own self-antigens. Autoimmune correct answers The _______ damage is caused by the autoantibodies and T-cells, to the extent that tissue damage occurs. Presenting clinical manifestations will depend on the area of the body affected. Regardless of the affected body area, autoantibodies and T-cells, and in some cases, B-cells, react in the associated body system to produce the characteristic signs and symptoms. Rheumatoid Arthritis, Systemic Lupus Erythematosus, Multiple Sclerosis, and Sjogren's Syndrome. correct answers Autoimmune diseases include: Systemic Lupus Erythematosus (SLE) correct answers Common Manifestations Tissue inflammation, vasculitis, rash, tissue inflammation. Immune System Changes Autoantibodies and auto-active T-cells against DNA and nucleoprotein antigens Rheumatoid Arthritis (RA) correct answers Common Manifestations Joint inflammation, stiffness and pain; loss of range of motion Immune System Changes Autoantibodies and auto-reactive T-cells and B-cells against joint-associated antigens Multiple Sclerosis (MS) correct answers Common Manifestations Formation of sclerotic plaque in the brain; leads to muscle weakness and ataxia Immune System Changes Autoantibodies and auto-reactive T-cells against brain antigens Sjogren's Syndrome correct answers Common Manifestations Inflammation in salivary and lacrimal glands Immune System Changes Autoantibodies and auto-reactive T-cells against apoptotic cells