ABFM ITE questions with correct answers

CAP antibiotic that causes VF - Answer Azithromycin - The arrhythmia results from prolongation of the QT interval and is also more common in patients with a prior cardiac history. Anti-DM medications for weight loss - Answer GLP1 receptor agonists e.g. Exenatide SGLT-2 inhibitor e.g. Canagliflozin Screening test with greatest potential for over diagnosis - Answer PSA Clinical manifestation of amyotrophic lateral sclerosis - Answer Asymmetric leg weakness Opioid to avoid in palliative patient with severe hepatic dysfunction - Answer Methadone - It is metabolized and cleared by the liver, and should therefore not be used in patients with severe hepatic impairment. It is, however, a reasonable option for patients with severe renal impairment. Lung cancer screening with low dose CT Chest annually - Answer Adults 55-80yo with 30 pack year history and currently smoking or quit within last 15 years NOAC with reversal agent - Answer Dabigatran Reduces alcoholism but creating an acute ethanol sensitivity - Answer Disulfiram Antidepressant to be avoided in the elderly - Answer Paroxetine (associated with more anticholinergic effects) SSRIs > SNRIs, atypical antipsychotics may be added for resistant depression Age group between which American Academy of Pediatrics recommends administration of an autism-specific screening tool - Answer 18-24 months old Most common neurological complication of Paget's disease