NRNP6566 week 9 Knowledge check

NRNP6566 week 9 Knowledge check The factors considered when prescribing antibiotics empirically include the site of infection and the organism most likely colonizing the site, prior knowledge of microorganism that is known to colonize the patient, and local bacterial resistance patterns or antibiograms of important pathogens that are available in most hospitals (Leekha et al., 2011). For a patient suspected with otitis media, the most common bacterial pathogens in the middle ear are Streptococcus pneumoniae and Haemophilus influenzae, with Moraxella catarrhalis as the third most common bacterial etiology. For adults with suspected uncomplicated otitis media, Amoxicillin is the preferred drug of choice, 875 mg PO BID or 500 mg PO TID for 5-7 days, as the said microorganisms are susceptible to it. For patients with recurrent otitis media or uncomplicated otitis media for immunicompromised patients, Amoxicillin-clavulanate 875/125 mg PO BID for 7-10 days or 10-14 days respectively. If the patient received an antibiotic in the past month, a second line of antibiotics can be used. These include cefdinir or cefuroxime which are cephalosphorins which are sensitive against gram negative bacteria. Reference Leekha, S., Terrell, C. L., & Edson, R. S. (2011). General Principles of Antimicrobial Therapy. Mayo Clinic Proceedings, 86(2), 156- 167.