Maryville NURS 615 Pharm test 3 ACTUAL EXAM 2023 GRADED A+

Maryville NURS 615 Pharm test 3 ACTUAL EXAM 2023 GRADED A+ 1. How do antigout medications work?: by inhibiting the infiltration and phagocytosis of leukocytes, thus decreasing the breakdown of uric acid to urate crystals. 2. Deposition of urate crystals causes: pain and inflammation 3. What is Colchicine: anti-gout medication 4. how does Colchicine work?: Works by inhibiting inflammation, reducing pain and swelling 5. common side effects of Colchicine: GI problems (diarrhea) use with caution in elderly Also can cause blood dyscrasias & abdominal pain 6. patient education with Colchicine: Can be given with food & milk to decrease GI issues Avoid beer, ale, & wine: may cause gout attack Increase fluid intake: increases excretion of uric acid Avoid smoked meats & high-protein diets 7. Low dose of Colchicine: Low dose colchicine is 1.2mg followed by 0.6mg one hour later or 1.8 milligrams total 8. High dose of Colchicine: high dose colchicine is 1.2mg followed by 0.6mg every four to six hours; or 4.8mg total. 9. Difference between high dose and low dose Colchicine: The difference between the two is low dose is as effective as high dose with a lower side effect profile. 10. Lab values to monitor with Colchicine: Check renal function test, BUN, Creatine 11. Patient education with Colchicine: Almost always causes some degree of diarrhea, make sure patients are aware of this side effect 12. Patient education with Febuxostat (Uloric): Gout may worsen with therapy initially 13. Dietary changes to decrease gout attacks and uric acid deposits.: Avoid beer, ale, & wine Increase fluid intake: increases excretion of uric acid Avoid smoked meats & high-protein diets 14. WHO 3 step ladder for pain medication: