GI tract anti-emetics
Nausea – wavelike sensation that may or may not culminate in vomiting
Retching – Gastric and oesophageal movements of vomiting without expulsion of
vomitus
Vomiting - Forceful expulsion of the contents of the: stomach, duodenum, or
jejunum through the oral cavity.
Causes of nausea and vomiting:
Anti-emetics act to centrally inhibit emesis and include antagonists of:
D2
5-HT3
H1
mACh
Pro-kinetic drugs act to promote gastric emptying this includes:
Drugs acting directly on smooth muscle
Drugs that act on the enteric nervous system
D2 receptor antagonists:
Phenothiazines: chlorpromazine and Acepromazine
Nausea – wavelike sensation that may or may not culminate in vomiting
Retching – Gastric and oesophageal movements of vomiting without expulsion of
vomitus
Vomiting - Forceful expulsion of the contents of the: stomach, duodenum, or
jejunum through the oral cavity.
Causes of nausea and vomiting:
Anti-emetics act to centrally inhibit emesis and include antagonists of:
D2
5-HT3
H1
mACh
Pro-kinetic drugs act to promote gastric emptying this includes:
Drugs acting directly on smooth muscle
Drugs that act on the enteric nervous system
D2 receptor antagonists:
Phenothiazines: chlorpromazine and Acepromazine
