Pharmacology A Patient-Centered Nursing Process Approach Chapter 1

Absorption - movement of drug particles from GI tract to body fluids by passive absorption, active aborption or pinocytosis Active absorption - requires a carrier such as an enzyme or protein to move the drug against a concentration gradient. autonomy - independence, the right to self determination Beneficence - duty to protect research subjects from harm disintegration - breakdown of tablet into smaller particles dissolution - breakdown of small particles in GI fluid before absorption excipients - fillers and inert substances included in tablets how are most oral drugs absorbed? - surface area of the SI through the action of the extensive mucosal villi informed consent - an ethical principle that research participants have the right to be informed and participation is voluntary