Maryville NURS 615 Pharm 3 exam with all the correct answers (100% Verified 2020/2021 exam)

Maryville NURS 615 Pharm 3 exam with all the correct answers (100% Verified 2020/2021 exam) How do antigout medications work? Correct Answer- by inhibiting the infiltration and phagocytosis of leukocytes, thus decreasing the breakdown of uric acid to urate crystals. Deposition of urate crystals causes Correct Answer- pain and inflammation What is Colchicine Correct Answer- anti-gout medication how does Colchicine work? Correct Answer- Works by inhibiting inflammation, reducing pain and swelling common side effects of Colchicine Correct Answer- GI problems (diarrhea) use with caution in elderly Also can cause blood dyscrasias & abdominal pain patient education with Colchicine Correct Answer- Can be given with food & milk to decrease GI issues Avoid beer, ale, & wine: may cause gout attack Increase fluid intake: increases excretion of uric acid Avoid smoked meats & high-protein diets Low dose of Colchicine Correct Answer- Low dose colchicine is 1.2mg followed by 0.6mg one hour later or 1.8 milligrams total High dose of Colchicine Correct Answer- high dose colchicine is 1.2mg followed by 0.6mg every four to six hours; or 4.8mg total. Difference between high dose and low dose Colchicine Correct Answer- The difference between the two is low dose is as effective as high dose with a lower side effect profile. Lab values to monitor with Colchicine Correct Answer- Check renal function test, BUN, Creatine Patient education with Colchicine Correct Answer- Almost always causes some degree of diarrhea, make sure patients are aware of this side effect Patient education with Febuxostat (Uloric) Correct Answer- Gout may worsen with therapy initially Dietary changes to decrease gout attacks and uric acid deposits. Correct Answer- Avoid beer, ale, & wine Increase fluid intake: increases excretion of uric acid Avoid smoked meats & high-protein diets WHO 3 step ladder for pain medication Correct Answer- What is not a first line for pain medication? Correct Answer- Narcotics Recommendations for pain treatment Correct Answer- You want to start with NSAIDs first and then work your way up from there. types of Corticosteroid treatment Correct Answer- Prednisone, Cortisone, Dexamethasone how do Corticosteroids work? Correct Answer- Suppress the inflammatory & immune systems by inhibiting the synthesis of chemical mediators. what are the chemical mediators that Corticosteroids work on? Correct Answer- Prostaglandins, leukotrienes, & histamines Corticosteroids and inflammation Correct Answer- Decreases inflammation which decreases swelling, warmth, redness, & pain. Uses for corticosteroid treatment Correct Answer- Addison's disease, hormone replacement, cancer therapy SLE, arthritis, IBD, & to suppress graft rejection