NR 565 Final Exam Study Guide May 2022

NR 565 Final Exam Study Guide May 2022 Week 5 1) Signs and symptoms of hypothyroidism and hyperthyroidism Hypothyroidism: Thick, coarse, dry Hyporeflexia, "hung up" patella reflex Slow thought process, Weight gain (5-10 lbs./2.25-4.5 kg) Constipation, Menorrhagia, Cold intolerance: Cold all the time Hyperthyroidism (aka graves disease): Smooth, silky Hyperreflexia, Mind racing, Weight loss (10 lbs./4.5 kg) Diarrhea, loose, frequent stools, Oligomenorrhea, Heat intolerance: Hot all the time 2) What adjunctive therapy is good to prescribe to control symptoms of hyperthyroidism other than thyroid specific medications? Know drug classes and examples of those drug classes. β-Blockers and nonradioactive iodine may be used as adjunctive therapy. β-Blockers suppress tachycardia by blocking β-receptors on the heart. Nonradioactive iodine inhibits synthesis and release of thyroid hormones. 3) Monitoring needs and intervals for thyroid medications. levothyroxine-Monitoring: Check TSH 6-8 weeks after initiating therapy and after any dosage change. Check TSH at least once a year after serum TSH is stabilized. Methimazole-Monitoring: Check CBC with differential if signs or symptoms of infection. Check LFTs if signs or symptoms of liver dysfunction. Propylthiouracil (PTU)- Treatment continues for 1-2 years PTU has caused rare cases of liver injury. Onset is sudden and progression is rapid