NUR2474 Pharmacology Module 2 Quiz Review

NUR2474 Pharmacology Module 2 Quiz Review Topics review: 1. General features of Alzheimer’s Disease on Donepezil a. Alzheimer’s is uncurable, cannot be delayed/slowed, or reversed. However cognitive decline can be slowed down. b. Donepezil i. Indicated for mild, moderate or severe AD ii. Affects ACh levels iii. Take acetaminophen (Tylenol) instead of NSAIDs (aspirin or ibuprofen) iv. Inhibition/prevention to breakdown Acetylcholine (ACh) v. Common side effects 1. Nausea, vomiting, GI discomfort (diarrhea), dyspepsia (indigestion), headache, fainting, falls/fall-related fractures. 2. Questions on key neuro meds see table below (mechanism of action, side/adverse effect, administration, etc.): Especially, Donepezil, Interferon beta, Carbamazepine, Methylphenidate a. Interferon-beta i. Multiple Sclerosis ii. Immunomodulators iii. How it works? 1. Reduces severity and frequency of attacks 2. Reduces development of brain lesions detectable by magnetic resonance imaging (MRI) 3. Delays progression of disease iv. Naturally occurring glycoprotein with antiviral, antiproliferative, and immunomodulatory actions. v. Immunosuppressive quality 1. Inhibits WBC 2. Inhibits T-helper cells vi. Does not prevent or cause infection but can make an infection worse. vii. May cause FLU-LIKE symptoms, not actually cause the flu. viii. Injection reactions 1. No warm or cold compress a. Do not change the temperature of the tissue 2. Benadryl if needed 3. Hydrocortisone cream if needed 4. Rotate injection sites to avoid injection site reactions and skin break down ix. Can cause depression and suicidal thoughts x. Allow 48 hours between injections xi. Start with low dose then increase too more.