Biology II - Unit III Notes

Central dogma

nucleus cell
ribosome
Sphase polypeptide
cytoplasm

DNAreplication transcription translation
DNA RNA RNA protein
dsDNA ssDNA


Discoveries

Griffith Streptococcuspneumoniae mice experiment
Smooth S Rough R
capsule sticky surroundsand
Ocassule
stickstotissues infection

pathogenic non pathogenic


too
swings 9

i
Refined



Transformation change in genotypephenotypecelltaking Dna environment
6recombinantplasmids develop antibioticresistance grewamphicilin

very Mcleod Mccarty isolate moleculeresponsible transformations
killedScens

Protein C
Trypsinchymotrypsin
u INA
RNA Deoxribonucleoderdgmerase
Ribonuclease
u
seems appear

ashes Chase Dna transferredbacteriophages

By 355 proteinsmethioninecysteine liquid phage
proteigmeaso

, at p conas MAD poet phage Dna
radio as



on rat i r na alsotransmitgenes

hangoff basepainingnucleotidesDNA
atson Crick 3D model DNA

eselson Stans test semi consenatve

E roti in 15N dank

medium can aight
c
s
conservative u
Dispersive
semi conservative




any other middle bands




DNAReplication prokaryotes

opendsDNA Dna helicase ch bonds Ssnp topoisomerase phosphodiesterbonds

Prime RNAfragment primase primer 5 3

Extend on a polymerase in adds nucleoside trphosphates nucleosidesmonophosphates
loses a phosphates water

leadingStrand Igginsstrands
Okazaki fragments

Telomeres avoid overhangs non codingDNA
4 RNARomer DNA Dna
oagmenase I

Ligate ends DNA ligase
DNADamage Repair endogenous exogenous