Organic Medicinal Chemistry Q&A

PACOP REVIEWER (2017) Organic Medicinal Chemistry MULTIPLE CHOICE 1. Decarboxylation of L-dihydroxyphenylalanine produces A. Tyrosine D. Dopamine B. Epinephrine E. Norepinephrine C. Ephedrine ANS: D 2. Drugs with superior lipid solubility usually possess what moiety A. Oxygen D. Sulfur B. Nitrogen E. Fluorine C. Chlorine ANS: D 3. The compound that reacts to salicylic acid to make aspirin is an example of a(n) A. Alcohol D. Acid anhydride B. Ketone E. Ester C. Ether ANS: D 4. The major product (Aspirin) is prone to hydrolysis, which of the following is/are the product/s of its hydrolysis? A. Carboxylic acid D. Both A and B B. Alcohol E. Both A and C C. Ester ANS: D 5. When aspirin has been hydrolyzed, one of its products produces a keratolytic property, what is that product? A. Salicylic acid D. Methyl salicylate B. Undecylenic acid E. Alcohol C. Ester ANS: A