Chapter 16: Drugs Affecting the Cardiovascular and Renal
Systems
Multiple Choice
Identify the choice that best completes the statement or answers the question.
__C__ 1. Ray has been diagnosed with hypertension and an ACE inhibitor is
determined to be needed. Prior to prescribing this drug, the NP should
assess for:
A. Hypokalemia
B. Impotence
C. Decreased renal function
D. Inability to concentrate
__D__ 2. ACE inhibitors are the drug of choice in treating hypertension in
diabetic patients because they:
A. Improve insulin sensitivity
B. Improve renal hemodynamics
C. Reduce the production of
angiotensin II
D. All of the above
_A___ 3. A potentially life-threatening adverse response to ACE inhibitors is
angioedema. Which of the following statements is true about this
adverse response?
A. Swelling of the tongue or
hoarseness are the most
common symptoms.
B. It appears to be related to the
decrease in aldosterone
production.
C. Presence of a dry, hacky cough
indicates a high risk for this
adverse response.
D. Because it takes time to build up
a blood level, it occurs after
being on the drug for about 1
week.
__C__ 4. ACE inhibitors are useful in a variety of disorders. Which of the
following statements are true about both its usefulness in the disorder
and the reason for its use?
A. Stable angina because it
decreases the thickening of
vascular walls to decreased MOD.
, B. Heart failure because it reduces
remodeling of injured myocardial
tissues.
C. Both A and B are true and the
reasons are correct
D. Both A and B are true but the
reasons are wrong
E. Neither A nor B are true
__B__ 5. Despite good blood pressure control, a NP might change a patient’s
drug from an ACEI to an angiotensin II receptor blocker (ARB) because
the ARB:
A. Is stronger than the ACEI
B. Does not produce a dry, hacky
cough
C. Has no effect on the renal system
D. Reduces sodium and water
retention
__C__ 6. While taken an ARB, patients need to avoid certain over-the-counter
drugs without first consulting the provider because:
A. Cimetidine is metabolized by the
CYP 3A4 isoenzymes
B. Nonsteroidal anti-inflammatory
drugs reduce prostaglandin
levels
C. Both A and B
D. Neither A nor B
__C__ 7. Laboratory monitoring for patients on ACEIs or ARBs should include:
A. White blood cells counts with the
drug dose increased for
elevations above 10,000
B. Liver function tests with the drug
dose stopped for ALT values 2
normal
C. Serum creatinine levels with the
drug dose reduced for values
above 2.5 mg/dL
D. Serum glucose levels with the
drug dose increased for levels
above 120 mg/dL
__A__ 8. Jacob has hypertension for which a calcium channel blocker has been
prescribed. This drug helps control blood pressure because it:
Systems
Multiple Choice
Identify the choice that best completes the statement or answers the question.
__C__ 1. Ray has been diagnosed with hypertension and an ACE inhibitor is
determined to be needed. Prior to prescribing this drug, the NP should
assess for:
A. Hypokalemia
B. Impotence
C. Decreased renal function
D. Inability to concentrate
__D__ 2. ACE inhibitors are the drug of choice in treating hypertension in
diabetic patients because they:
A. Improve insulin sensitivity
B. Improve renal hemodynamics
C. Reduce the production of
angiotensin II
D. All of the above
_A___ 3. A potentially life-threatening adverse response to ACE inhibitors is
angioedema. Which of the following statements is true about this
adverse response?
A. Swelling of the tongue or
hoarseness are the most
common symptoms.
B. It appears to be related to the
decrease in aldosterone
production.
C. Presence of a dry, hacky cough
indicates a high risk for this
adverse response.
D. Because it takes time to build up
a blood level, it occurs after
being on the drug for about 1
week.
__C__ 4. ACE inhibitors are useful in a variety of disorders. Which of the
following statements are true about both its usefulness in the disorder
and the reason for its use?
A. Stable angina because it
decreases the thickening of
vascular walls to decreased MOD.
, B. Heart failure because it reduces
remodeling of injured myocardial
tissues.
C. Both A and B are true and the
reasons are correct
D. Both A and B are true but the
reasons are wrong
E. Neither A nor B are true
__B__ 5. Despite good blood pressure control, a NP might change a patient’s
drug from an ACEI to an angiotensin II receptor blocker (ARB) because
the ARB:
A. Is stronger than the ACEI
B. Does not produce a dry, hacky
cough
C. Has no effect on the renal system
D. Reduces sodium and water
retention
__C__ 6. While taken an ARB, patients need to avoid certain over-the-counter
drugs without first consulting the provider because:
A. Cimetidine is metabolized by the
CYP 3A4 isoenzymes
B. Nonsteroidal anti-inflammatory
drugs reduce prostaglandin
levels
C. Both A and B
D. Neither A nor B
__C__ 7. Laboratory monitoring for patients on ACEIs or ARBs should include:
A. White blood cells counts with the
drug dose increased for
elevations above 10,000
B. Liver function tests with the drug
dose stopped for ALT values 2
normal
C. Serum creatinine levels with the
drug dose reduced for values
above 2.5 mg/dL
D. Serum glucose levels with the
drug dose increased for levels
above 120 mg/dL
__A__ 8. Jacob has hypertension for which a calcium channel blocker has been
prescribed. This drug helps control blood pressure because it:
