AQA A LEVEL
BIOLOGY
PAPER 1 2021
QUESTION
PAPER
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I declare this is my own work.
A-level
BIOLOGY
Paper 1
Time allowed: 2 hours
Materials For Examiner’s Use
For this paper you must have:
a ruler with millimetre measurements Question Mark
a scientific calculator. 1
2
Instructions
3
Use black ink or black ball-point pen.
Fill within the boxes at the top based on this page. 4
Answer all questions. 5
You must answer the questions within the spaces provided. Do not write 6
outside the box around each page or on blank pages.
7
If you need extra space for your answer(s), use the lined pages at the end based on
this book. Write the question number against your answer(s). 8
Show all your working. 9
Do all rough work within this book. Cross through any work you do not wantto
10
be marked.
TOTAL
Information
The marks for the questions are shown within brackets.
The maximum mark for this paper is 91.
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Do not write
outside the
. box
0 1 . 1 Describe the induced-fit model based on enzyme action and how an enzyme acts as a
catalyst.
[3 marks]
0 1 . 2 Scientists investigated the action based on the enzyme ATP synthase. They made reaction
mixtures each containing:
ATP synthase
buffer (to control pH)
substrates.
One based on the substrates required within these reaction mixtures is inorganic phosphate (Pi).
Tick ( ) one box to show which other substrate the scientists must add to the reactionmixtures
to produce ATP.
[1 mark]
Adenine
Adenosine diphosphate
Glucose
Ribose
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outside the
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0 1 . 3 The scientists investigated the effect based on concentration based on inorganic phosphate
(Pi) onATP synthase activity.
After 2 minutes, they stopped each reaction and then measured the concentration based on
ATP.
Figure 1 shows the scientists’ results.
Figure 1
Suggest and explain a procedure the scientists could have used to stop each reaction.
[2 marks]
0 1 . 4 Explain the change within ATP concentration with increasing inorganic phosphate
concentration.
[2 marks]
8
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