NSG 6005 FINAL STUDY GUIDE VERIFIED 100%

FINAL STUDY GUIDE PREVIOUS EXAM INFO Guanfacine- used to treat HTN or ADHD, non stimulant. Alpha 2 adrenergic agonist.Antiarrhythmics start on p. 322Class I: sodium channel blockersClass Ia: lengthens action potential (quinidine, procainamide [requires freq. dosing], disopyramide)Class Ib: shortens action potential (lidocaine, phenytoin) treats ventricular arrhythmiasClass Ic: minimal or no effect on action potential; severe ventricular tachycardias- where no other drugs have workedClass II: beta blockers (propranolol, metoprolol, atenolol)- indirectly reduces slope by blocking chronotropic impact of norepinephrineAtenolol has longer half-life than metoprololClass III: agents that lengthen action potential (potassium channel blockers) - (amiodarone, bretyllium) effective in treating re-entry problems, inhibits v-fib due to myocardial ischemia, improves contractilityClass IV: Calcium channel blockers (verapamil, diltiazem, bepridil) & (amlodipine, felodipine)2 types of CCB: type I- non-hydropyridines-affect conduction through AV node, have neg chronotropic effect (verapamil, diltiazem)type II: hydorphyridines-do not affect conduction through AV node (nifedipine, amlodipine, felodipine)Class IA & IC -what is similar?Lidocaine- Amiodaraone effective against supraventricular rhythmsBPH & HTN medDoxazosin- used to treat BPH & HTNMexiletine- only available orally Valerian has no adverse reactions when used at the recommended level; however, overdosage at 2.5 g or more can cause cardiac disturbance, excitability, headache, insomnia, and nausea. It can potentiate alcohol and other CNS depressants if taken in large amounts. (p. 139)Ayurvedic medicine- Although all three doshas exist together, often plants and people are classified by the one that is most dominant in them, referred to as the person's "Prakruti," and specific to them as an individual. (p. 132)Glaucoma meds:Longer eyelashes-lanasoprost or bimatoprost - prostaglandin drugsGlaucoma med cause blurriness after instilled into eyes for few minutesProcainamide-short acting; need dose reduction in CHF and renal impairment (p. 325)VLDL- synthesized in the liver (p. 1130) Drugs that inhibit VLDL synthesis in the liver (niacin, fibric acid derivatives) also reduce LDLs via the endogenous pathway (p.1130).Cholesterol meds:-acted on sterols