BIOM 500 QUIZ 7 2020 Questions With Correct Answers (100% Verified)

BIOM 500 QUIZ 7 2020 Questions With Correct Answers (100% Verified) This drug exerts its anticancer effects by inhibiting the enzyme - dihydrofolate reductase thereby depleting the cellular folate pool and inhibiting de novo purine synthesis; Selected Answer: Methotrexa te Correct Answer: Methotrexa te • Question 2 1.5 out of 1.5 points You are evaluating apatient with a cancer type that is characterized by constitutive expression of NFϏB - which promotes oncogenesis, Bortezomib will be most effective in managing the patient. Selected Answer: True Correct Answer: Tru e • Question 3 2 out of 2 points This therapeutic target is involved in DNA repair and works by inserting double-stranded breaks in DNA; Selected Answer: Topoisomerase II Correct Answer: Topoisomerase II • Question 4 Match these chemotherapeutic agents to their plant sources; QuestionCorrect Match Selected Match 1 out of 1 points Irinoteca n A. Chinese Yew Tree A. Chinese Yew Tree Paclitaxel B. Pacific Yew Tree (Bark) B. Pacific Yew Tree (Bark) Vinblasti ne C. Pink Periwinkle C. Pink Periwinkle • Question 5 2 out of 2 points The functionalmodality of an anantibodythat is composed of VL + CL and VH + CH1 is the; Selected Answer: Fragment of antigen binding Correct Answer: Fragment of antigen binding • Question 6 2 out of 2 points Which of these agents targets the tyrosine kinase domain of the fusion protein formed from the Philadelphia chromosome and will be helpful in chronic myelogenous leukemia? Selected Answer: Imatini b Correct Answer: Imatini b • Question 7 The most commonly used Ig isotype used in cancer immunotherapy is;