PATHOPHYSIOLOGY: THE BIOLOGIC BASIS FOR
DISEASE IN ADULTS AND CHILDREN, 8th Edition.
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PATHOPHYSIOLOGY
THE BIOLOGIC BASIS FOR DISEASE IN ADULTS AND CHILDREN
8th Edition
Kathryn L. McCance, Sue E. Huether
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Contents
Chapter 01: Cellular Biology........................................................................................................4
Chapter 02: Altered Cellular and Tissue Biology: Environmental Agents ...................................18
Chapter 03: The Cellular Environment: Fluids and Electrolytes, Acids and Bases .....................31
Chapter 04: Genes and Genetic Diseases ................................................................................44
Chapter 05: Genes, Environment-Lifestyle, and Common Diseases .........................................55
Chapter 06: Epigenetics and Disease .......................................................................................63
Chapter 07: Innate Immunity: Inflammation and Wound Healing ...............................................68
Chapter 08: Adaptive Immunity .................................................................................................83
Chapter 09: Alterations in Immunity and Inflammation ..............................................................95
Chapter 10: Infection ...............................................................................................................108
Chapter 11: Stress and Disease..............................................................................................117
Chapter 12: Cancer Biology ....................................................................................................124
Chapter 13: Cancer Epidemiology...........................................................................................137
Chapter 14: Cancer in Children ...............................................................................................143
Chapter 15: Structure and Function of the Neurologic System ................................................148
Chapter 16: Pain, Temperature Regulation, Sleep, and Sensory Function ..............................159
Chapter 17: Alterations in Cognitive Systems, Cerebral Hemodynamics, and Motor Function .174
Chapter 18: Disorders of the Central and Peripheral Nervous Systems and the Neuromuscular
Junction
..........................................................................................................................................................
........ 188
Chapter 19: Neurobiology of Schizophrenia, Mood Disorders, and Anxiety Disorders .............199
Chapter 20: Alterations of Neurologic Function in Children......................................................206
Chapter 21: Mechanisms of Hormonal Regulation ..................................................................213
Chapter 22: Alterations of Hormonal Regulation......................................................................222
Chapter 23: Obesity and Disorders of Nutrition .......................................................................234
Chapter 24: Structure and Function of the Reproductive Systems ..........................................239
Chapter 25: Alterations of the Female Reproductive System ..................................................249
Chapter 26: Alterations of the Male Reproductive System.......................................................259
Chapter 27: Sexually Transmitted Infections ...........................................................................265
Chapter 28: Structure and Function of the Hematologic System .............................................273
Chapter 29: Alterations of Erythrocytes, Platelets, and Hemostatic Function ...........................283
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Chapter 30: Alterations of Leukocyte and Lymphoid Function .................................................293
Chapter 31: Alterations of Hematologic Function in Children ...................................................300
Chapter 32: Structure and Function of the Cardiovascular and Lymphatic Systems ................311
Chapter 33: Alterations of Cardiovascular Function.................................................................324
Chapter 34: Alterations of Cardiovascular Function in Children ...............................................338
Chapter 35: Structure and Function of the Pulmonary System ................................................346
Chapter 36: Alterations of Pulmonary Function .......................................................................356
Chapter 37: Alterations of Pulmonary Function in Children......................................................373
Chapter 38: Structure and Function of the Renal and Urologic Systems .................................381
Chapter 39: Alterations of Renal and Urinary Tract Function ...................................................391
Chapter 40: Alterations of Renal and Urinary Tract Function in Children .................................401
Chapter 41: Structure and Function of the Digestive System...................................................409
Chapter 42: Alterations of Digestive Function..........................................................................421
Chapter 43: Alterations of Digestive Function in Children ........................................................432
Chapter 44: Structure and Function of the Musculoskeletal System ........................................441
Chapter 45: Alterations of Musculoskeletal Function ...............................................................453
Chapter 46: Alterations of Musculoskeletal Function in Children .............................................466
Chapter 47: Structure, Function, and Disorders of the Integument ..........................................475
Chapter 48: Alterations of the Integument in Children .............................................................486
Chapter 49: Shock, Multiple Organ Dysfunction Syndrome, and Burns in Adults.....................494
Chapter 50: Shock, Multiple Organ Dysfunction Syndrome, and Burns in Children .................502