HESI Med Surg Exam 2026-2027 500+
QUESTIONS AND ANSWERS ALREADY
GRADED A+. 100% Verified Solutions | Updated
Per Latest Elsevier HESI Standards | Graded A+
This comprehensive study guide contains 600+ verified questions and answers for
the HESI Medical-Surgical Examination, covering all essential domains including
cardiovascular, respiratory, gastrointestinal, endocrine, renal, neurological,
musculoskeletal, oncology, and perioperative care. Designed for nursing students
(RN and PN) preparing for HESI specialty exams and NCLEX success, this
resource reflects the latest 2026/2027 Elsevier HESI testing standards and
incorporates Next Generation NCLEX (NGN) item types. Each question is
accompanied by detailed rationales to reinforce learning and ensure exam
readiness.
Abstract
This document serves as a definitive preparation resource for the HESI Med-Surg
Examination, aligned with the latest 2026/2027 Elsevier HESI blueprint and the
NCSBN NCLEX-RN/PN test plan. The 600+ verified questions are systematically
organized into core content areas reflecting the official HESI Med-Surg exam
blueprint: Cardiovascular System, Respiratory System, Gastrointestinal System,
Endocrine & Metabolic Disorders, Renal & Urinary System, Neurological System,
Musculoskeletal System, Hematologic & Immune System, Oncology,
Perioperative Care, and Clinical Judgment (NGN-style). Each question is
meticulously crafted to mirror the exam's format and difficulty, with answers
graded A+ by subject matter experts. Detailed rationales elucidate correct
responses and explain common distractor traps, promoting deep conceptual
understanding . The guide emphasizes practical application through scenario-based
questions and case studies that simulate real-world nursing situations . Updated to
incorporate the latest evidence-based practices and Next Generation NCLEX
(NGN) item types, this resource ensures candidates are thoroughly prepared to
achieve exam success .
,Content Area Overview:
Content Area Questions Key Topics Weight
Heart failure, MI,
Cardiovascular hypertension, arrhythmias,
1-100 17%
System PVD, DVT, EKG
interpretation
COPD, asthma, pneumonia,
Respiratory System 101-170 PE, ARDS, oxygen therapy, 12%
ABG interpretation
PUD, cirrhosis, pancreatitis,
Gastrointestinal
171-230 IBD, ostomy care, GI 10%
System
bleeding, hepatic failure
Diabetes (DKA, HHS),
Endocrine &
231-290 thyroid disorders, adrenal 10%
Metabolic Disorders
insufficiency, Cushing's
AKI, chronic kidney disease,
Renal & Urinary
291-340 UTI, dialysis, kidney stones, 8%
System
catheter care
Stroke, increased ICP,
Neurological
341-390 seizures, Parkinson's, MS, 8%
System
Alzheimer's, spinal cord
,Content Area Questions Key Topics Weight
Fractures, osteoporosis, joint
Musculoskeletal
391-420 replacement, compartment 5%
System
syndrome, gout
Chemotherapy, radiation,
Oncology 421-470 tumor lysis syndrome, 8%
palliative care, alopecia
Preoperative, intraoperative,
Perioperative Care 471-510 PACU, complications, pain 7%
management, discharge
Unfolding case studies, bow-
Clinical Judgment
511-600 tie, matrix, SATA, 15%
(NGN-Style)
prioritization, delegation
SECTION 1: CARDIOVASCULAR SYSTEM (Questions 1-100)
Question 1: A client with heart failure has jugular venous distention, 3+ pitting
edema, and crackles in the lung bases. Which medication should the nurse prepare
to administer first?
A) Digoxin
B) Metoprolol
C) Furosemide
D) Spironolactone
Answer: C) Furosemide
Rationale: Furosemide is a loop diuretic that rapidly reduces preload and relieves
pulmonary congestion. These signs indicate fluid overload requiring immediate
intervention. Digoxin and beta-blockers are chronic therapies; spironolactone is a
potassium-sparing diuretic used as an adjunct .
, Question 2: A client with atrial fibrillation is prescribed warfarin. The nurse
should teach the client to avoid which food?
A) Apples
B) Rice
C) Broccoli
D) Chicken
Answer: C) Broccoli
Rationale: Broccoli and other green leafy vegetables are high in vitamin K, which
can antagonize warfarin's effect and lower the INR. Consistent intake is more
important than avoidance, but large variations should be avoided .
Question 3: A client presents with chest pain that radiates to the jaw, diaphoresis,
and nausea. The ECG shows ST-segment elevation. Which intervention should the
nurse implement first?
A) Administer sublingual nitroglycerin
B) Obtain a troponin level
C) Apply oxygen
D) Prepare for percutaneous coronary intervention
Answer: C) Apply oxygen
Rationale: Oxygen is the priority to increase myocardial oxygenation.
Nitroglycerin, pain management, and rapid transfer for PCI follow, but ensuring
adequate oxygenation comes first .
Question 4: The nurse is teaching a client with angina about sublingual
nitroglycerin. Which statement indicates the client needs further teaching?
A) "I will take the nitroglycerin at the first sign of chest pain."
B) "I will call 911 if the pain is not relieved after 3 doses."
C) "I will chew the tablet for faster absorption."
D) "I will keep the tablets in their original dark bottle."
Answer: C) "I will chew the tablet for faster absorption."
Rationale: Sublingual nitroglycerin should be placed under the tongue and
allowed to dissolve—not chewed. Chewing reduces effectiveness. The other
statements demonstrate correct understanding .
QUESTIONS AND ANSWERS ALREADY
GRADED A+. 100% Verified Solutions | Updated
Per Latest Elsevier HESI Standards | Graded A+
This comprehensive study guide contains 600+ verified questions and answers for
the HESI Medical-Surgical Examination, covering all essential domains including
cardiovascular, respiratory, gastrointestinal, endocrine, renal, neurological,
musculoskeletal, oncology, and perioperative care. Designed for nursing students
(RN and PN) preparing for HESI specialty exams and NCLEX success, this
resource reflects the latest 2026/2027 Elsevier HESI testing standards and
incorporates Next Generation NCLEX (NGN) item types. Each question is
accompanied by detailed rationales to reinforce learning and ensure exam
readiness.
Abstract
This document serves as a definitive preparation resource for the HESI Med-Surg
Examination, aligned with the latest 2026/2027 Elsevier HESI blueprint and the
NCSBN NCLEX-RN/PN test plan. The 600+ verified questions are systematically
organized into core content areas reflecting the official HESI Med-Surg exam
blueprint: Cardiovascular System, Respiratory System, Gastrointestinal System,
Endocrine & Metabolic Disorders, Renal & Urinary System, Neurological System,
Musculoskeletal System, Hematologic & Immune System, Oncology,
Perioperative Care, and Clinical Judgment (NGN-style). Each question is
meticulously crafted to mirror the exam's format and difficulty, with answers
graded A+ by subject matter experts. Detailed rationales elucidate correct
responses and explain common distractor traps, promoting deep conceptual
understanding . The guide emphasizes practical application through scenario-based
questions and case studies that simulate real-world nursing situations . Updated to
incorporate the latest evidence-based practices and Next Generation NCLEX
(NGN) item types, this resource ensures candidates are thoroughly prepared to
achieve exam success .
,Content Area Overview:
Content Area Questions Key Topics Weight
Heart failure, MI,
Cardiovascular hypertension, arrhythmias,
1-100 17%
System PVD, DVT, EKG
interpretation
COPD, asthma, pneumonia,
Respiratory System 101-170 PE, ARDS, oxygen therapy, 12%
ABG interpretation
PUD, cirrhosis, pancreatitis,
Gastrointestinal
171-230 IBD, ostomy care, GI 10%
System
bleeding, hepatic failure
Diabetes (DKA, HHS),
Endocrine &
231-290 thyroid disorders, adrenal 10%
Metabolic Disorders
insufficiency, Cushing's
AKI, chronic kidney disease,
Renal & Urinary
291-340 UTI, dialysis, kidney stones, 8%
System
catheter care
Stroke, increased ICP,
Neurological
341-390 seizures, Parkinson's, MS, 8%
System
Alzheimer's, spinal cord
,Content Area Questions Key Topics Weight
Fractures, osteoporosis, joint
Musculoskeletal
391-420 replacement, compartment 5%
System
syndrome, gout
Chemotherapy, radiation,
Oncology 421-470 tumor lysis syndrome, 8%
palliative care, alopecia
Preoperative, intraoperative,
Perioperative Care 471-510 PACU, complications, pain 7%
management, discharge
Unfolding case studies, bow-
Clinical Judgment
511-600 tie, matrix, SATA, 15%
(NGN-Style)
prioritization, delegation
SECTION 1: CARDIOVASCULAR SYSTEM (Questions 1-100)
Question 1: A client with heart failure has jugular venous distention, 3+ pitting
edema, and crackles in the lung bases. Which medication should the nurse prepare
to administer first?
A) Digoxin
B) Metoprolol
C) Furosemide
D) Spironolactone
Answer: C) Furosemide
Rationale: Furosemide is a loop diuretic that rapidly reduces preload and relieves
pulmonary congestion. These signs indicate fluid overload requiring immediate
intervention. Digoxin and beta-blockers are chronic therapies; spironolactone is a
potassium-sparing diuretic used as an adjunct .
, Question 2: A client with atrial fibrillation is prescribed warfarin. The nurse
should teach the client to avoid which food?
A) Apples
B) Rice
C) Broccoli
D) Chicken
Answer: C) Broccoli
Rationale: Broccoli and other green leafy vegetables are high in vitamin K, which
can antagonize warfarin's effect and lower the INR. Consistent intake is more
important than avoidance, but large variations should be avoided .
Question 3: A client presents with chest pain that radiates to the jaw, diaphoresis,
and nausea. The ECG shows ST-segment elevation. Which intervention should the
nurse implement first?
A) Administer sublingual nitroglycerin
B) Obtain a troponin level
C) Apply oxygen
D) Prepare for percutaneous coronary intervention
Answer: C) Apply oxygen
Rationale: Oxygen is the priority to increase myocardial oxygenation.
Nitroglycerin, pain management, and rapid transfer for PCI follow, but ensuring
adequate oxygenation comes first .
Question 4: The nurse is teaching a client with angina about sublingual
nitroglycerin. Which statement indicates the client needs further teaching?
A) "I will take the nitroglycerin at the first sign of chest pain."
B) "I will call 911 if the pain is not relieved after 3 doses."
C) "I will chew the tablet for faster absorption."
D) "I will keep the tablets in their original dark bottle."
Answer: C) "I will chew the tablet for faster absorption."
Rationale: Sublingual nitroglycerin should be placed under the tongue and
allowed to dissolve—not chewed. Chewing reduces effectiveness. The other
statements demonstrate correct understanding .
