11 August 2026
BMS 555 Test Exam2 100 comprehensive questions
|RECENT AND FREQUENTLY MOST TESTED QUESTIONS AND
VERIFIED SOLUTIONS/GET IT 100% ACCURATE!! 2026!!
PD-1 is a T cell receptor for PD-L1. What type of internal signaling motif is contained
within PD-1?
A. ITAM
B. ITIM
C. PIP2
D. IP3
B. ITIM
Calcineurin has what type of enzymatic activity?
A. Kinase
B. Phosphatase
C. Ligase
D. Polymerase
B. Phosphatase
IL2 signalling in T cells in response to costimulation can activate which of the following
proteins?
A. PI3K
B. PTEN
C. CXCL8
D. CCR7
A. PI3K
Phospholipase C converts PIP3 to IP3 and DAG.
A. True
B. False
B. False
Proteins with pleckstrin homology domains bind to what?
A. PIP3
B. PIP2
C. Phosphorylated tyrosines
D. Phosphorylated serines
,11 August 2026
A. PIP3
Proteins with an SH2 domain bind to what?
A. PIP3
B. PIP2
C. Phosphorylated tyrosines D. Phosphorylated serines
C. Phosphorylated tyrosines
Which of the following kinases is crucial for BCR signalling?
A. Bruton's tyrosine kinase
B. Lck kinase
C. ZAP-70
D. FGFR
A. Bruton's tyrosine kinase
Which of the following can be part of the BCR complex or a BCR coreceptor? (select all
that apply)
A. Membrane bound immunoglobulin
B. Igα:Igβ dimer
C. CD8
D. CD21
A. Membrane bound immunoglobulin
B. Igα:Igβ dimer
D. CD21
Antibodies can elicit effector functions through which of the following mechanisms?
(select all that apply)
A. Activation of classical complement pathway
B. Via Fc receptors on effector cells
C. Direct binding to TLRs
D. Presenting antigen to the TCR
A. Activation of classical complement pathway
B. Via Fc receptors on effector cells
The FcμR binds to which antibody subclass?
A. IgM
B. IgA
C. IgD
D. IgE
, 11 August 2026
A. IgM
The FcγR binds to which antibody subtype?
A. IgA
B. IgM
C. IgG
D. IgE
C. IgG
Variable domains show the highest degree of variability in amino acid sequence in what
part of the variable domain structure?
A. Beta strands
B. Loop regions
C. Beta barrel
D. Alpha helix
B. Loop regions
True or false: The avidity of F(ab')2 is greater than Fab
A. True
B. False
A. True
How many antigen binding sites in a typical antibody?
A. 1
B. 2
C. 3
D. 4
B. 2
How many variable domains in a typical antibody?
A. 1
B. 2
C. 3
D. 4
D. 4
Antibodies have how many light chains?
BMS 555 Test Exam2 100 comprehensive questions
|RECENT AND FREQUENTLY MOST TESTED QUESTIONS AND
VERIFIED SOLUTIONS/GET IT 100% ACCURATE!! 2026!!
PD-1 is a T cell receptor for PD-L1. What type of internal signaling motif is contained
within PD-1?
A. ITAM
B. ITIM
C. PIP2
D. IP3
B. ITIM
Calcineurin has what type of enzymatic activity?
A. Kinase
B. Phosphatase
C. Ligase
D. Polymerase
B. Phosphatase
IL2 signalling in T cells in response to costimulation can activate which of the following
proteins?
A. PI3K
B. PTEN
C. CXCL8
D. CCR7
A. PI3K
Phospholipase C converts PIP3 to IP3 and DAG.
A. True
B. False
B. False
Proteins with pleckstrin homology domains bind to what?
A. PIP3
B. PIP2
C. Phosphorylated tyrosines
D. Phosphorylated serines
,11 August 2026
A. PIP3
Proteins with an SH2 domain bind to what?
A. PIP3
B. PIP2
C. Phosphorylated tyrosines D. Phosphorylated serines
C. Phosphorylated tyrosines
Which of the following kinases is crucial for BCR signalling?
A. Bruton's tyrosine kinase
B. Lck kinase
C. ZAP-70
D. FGFR
A. Bruton's tyrosine kinase
Which of the following can be part of the BCR complex or a BCR coreceptor? (select all
that apply)
A. Membrane bound immunoglobulin
B. Igα:Igβ dimer
C. CD8
D. CD21
A. Membrane bound immunoglobulin
B. Igα:Igβ dimer
D. CD21
Antibodies can elicit effector functions through which of the following mechanisms?
(select all that apply)
A. Activation of classical complement pathway
B. Via Fc receptors on effector cells
C. Direct binding to TLRs
D. Presenting antigen to the TCR
A. Activation of classical complement pathway
B. Via Fc receptors on effector cells
The FcμR binds to which antibody subclass?
A. IgM
B. IgA
C. IgD
D. IgE
, 11 August 2026
A. IgM
The FcγR binds to which antibody subtype?
A. IgA
B. IgM
C. IgG
D. IgE
C. IgG
Variable domains show the highest degree of variability in amino acid sequence in what
part of the variable domain structure?
A. Beta strands
B. Loop regions
C. Beta barrel
D. Alpha helix
B. Loop regions
True or false: The avidity of F(ab')2 is greater than Fab
A. True
B. False
A. True
How many antigen binding sites in a typical antibody?
A. 1
B. 2
C. 3
D. 4
B. 2
How many variable domains in a typical antibody?
A. 1
B. 2
C. 3
D. 4
D. 4
Antibodies have how many light chains?
