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1. Antiparkinson- Carbidopa and Levodopa Action - Correct Answer:
Levodopa goes to brain cells to convert dopamine
Carbidopa blocks the conversion peripherally so levodopa can get to the
brain
2. Antiparkinson- Carbidopa and Levodopa Uses - Correct Answer: Treat
the signs and symptoms of Parkinson's Disease
Does NOT cure Parkinson's disease
3. Antiparkinson Drugs - Correct Answer: Carbidopa/Levodopa
4. Antiparkinson- Carbidopa and Levodopa Side Effects/Adverse Reactions
- Correct Answer: GI distress, dry mouth
Fatigue, insomnia, dizziness, headache, blurred vision
Dark urine
Orthostatic hypotension
Palpitations
Hypotension
Urinary retention
Psychosis, severe depression
,5. Antiparkinson- Carbidopa and Levodopa Contraindictions - Correct
Answer: Antipsychotics
MANY drug and food interactions
High protein foods decrease absorption
6. Antiparkinson- Carbidopa and Levodopa Assessment - Correct Answer:
Vital signs
Signs and symptoms of Parkinson's
Medical/medication history
7. Antiparkinson- Carbidopa and Levodopa Nursing Interventions - Correct
Answer: Monitor vital signs for orthostatic hypotension
Administer on empty stomach but may give with low protein food if
stomach upset occurs
High protein foods delay absorption
Monitor for signs and symptoms of Parkinson's
Monitor for suicidal ideation
8. Antiparkinson- Carbidopa and Levodopa Teach - Correct Answer: Take
on an empty stomach
Take at the same time each day
Take with low protein foods if stomach is upset (high protein foods affects
drug absorption)
Do not abruptly discontinue drugs
Levodopa may cause harmless discoloration of urine and sweat to brown
9. Acetylcholinesterase Inhibitors - Correct Answer: Donepezil- Helps with
Alzheimer's
Pyridostigmine- Helps with Myasthenia Gravis (MG)
,10.Acetylcholinesterase Inhibitors- Donezepil Action - Correct Answer:
Increases the amount of acetylcholine for use in the neuron receptors
mainly in the brain by inhibiting acetylcholinesterase
Does not alter progression of the disease, but can improve cognition
(attention and memory) and behavior and improve ability to engage in daily
activities
11.Acetylcholinesterase Inhibitors- Donezepil Uses - Correct Answer: FDA
approved for mild, moderate, and severe Alzheimer disease
12.Acetylcholinesterase Inhibitors- Donezepil Side Effects/Adverse Reactions -
Correct Answer: Most Common: GI upset, nausea, diarrhea, vomiting,
anorexia (with higher doses), avoid dehydration
Dizziness, drowsiness, headache
Hemolytic anemia, bleeding
Orthostatic hypotension
Bradycardia, AV block, syncope, chest pain
Seizures
13.Acetylcholinesterase Inhibitors- Donezepil Contraindications - Correct
Answer: Hypotension
Bradycardia
14.Acetylcholinesterase Inhibitors- Donezepil Interactions - Correct
Answer: NSAIDs- increase GI upset
Other drugs that cause bradycardia and hypotension
No alcohol- decreases effectiveness of drug
, 15.Acetylcholinesterase Inhibitors- Donezepil Assessment - Correct
Answer: Note client's cognitive and physical abilities- baseline dementia
assessment
Vital signs- not presence of cardiac issues, baseline weight
Medical/medication history
Family's copping/ability to manage care of client
16.Acetylcholinesterase Inhibitors- Donezepil Analyze Cues/Prioritize
Hypothesis (Client Problems) - Correct Answer: Maintain consistency in
care
Establish realistic expectations with the family
Record vital signs, especially weight
Monitor for side effects/adverse reactions/adherence treatment plan
Monitor for safety
Monitor for improvement or decline in function
Use interprofessional team approach
17.Acetylcholinesterase Inhibitors- Donezepil Teaching - Correct Answer:
Medication use and precautions for long-term use of AChE inhibitors
Drug will help with symptoms but not cure disease
Available support groups
May take with or without food to manage GI upset
Monitor intake and make foods that client enjoys
Best to take at bedtime
Safety for managing client who may wander or not understand how
common objects work