MMSC491 EXAM 3 LATEST
QUESTIONS AND
ANSWERS 2026 - 2027
What is the most appropriate gene therapy for treating cancer?
a. Repair of mutant gene
b. Modifying disease cells
c. Killing disease cells
d. Gene augmentation - ANSWERS-Killing disease cells
How do cancer cells avoid chromosome destabilization due to their
rapidly shortening telomeres? - ANSWERS-They express telomerase
In cancer cells, hypomethylation of DNA results in... - ANSWERS-
None of the above
Which of the following databases contains descriptions of genomic,
transcriptomic, and epigenetic changes in different types of tumors? -
ANSWERS-ICGC
Which of the following discoveries in cancer research is a direct result
of the advent of next-generation sequencing? - ANSWERS-
Extraordinary mutational diversity in tumors
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PAGE
1
, MMSC491 EXAM 3 LATEST
QUESTIONS AND
ANSWERS 2026 - 2027
Which of the following is not a method of oncogene activation? -
ANSWERS-RAS/RAF pathway activation
Which of the following is true about miRNA in cancer cells? -
ANSWERS-miRNAs have regulatory rules in apoptosis, cell-cycle
control and DNA damage responses
Which of the following can result from telomere instability in cancer
cells? - ANSWERS-The cell does not recognize the DNA as a
chromosome and fuses it to another chromosome
Which of the following regarding genome wide gene expression screens
is false? - ANSWERS-The hybridization probes bind to proteins within
the cell
Which of the following is defined as large numbers of chromosomal
rearrangements are generated in what appear to be single catastrophic
events? - ANSWERS-Chromothripsis
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PAGE
2
QUESTIONS AND
ANSWERS 2026 - 2027
What is the most appropriate gene therapy for treating cancer?
a. Repair of mutant gene
b. Modifying disease cells
c. Killing disease cells
d. Gene augmentation - ANSWERS-Killing disease cells
How do cancer cells avoid chromosome destabilization due to their
rapidly shortening telomeres? - ANSWERS-They express telomerase
In cancer cells, hypomethylation of DNA results in... - ANSWERS-
None of the above
Which of the following databases contains descriptions of genomic,
transcriptomic, and epigenetic changes in different types of tumors? -
ANSWERS-ICGC
Which of the following discoveries in cancer research is a direct result
of the advent of next-generation sequencing? - ANSWERS-
Extraordinary mutational diversity in tumors
END OF
PAGE
1
, MMSC491 EXAM 3 LATEST
QUESTIONS AND
ANSWERS 2026 - 2027
Which of the following is not a method of oncogene activation? -
ANSWERS-RAS/RAF pathway activation
Which of the following is true about miRNA in cancer cells? -
ANSWERS-miRNAs have regulatory rules in apoptosis, cell-cycle
control and DNA damage responses
Which of the following can result from telomere instability in cancer
cells? - ANSWERS-The cell does not recognize the DNA as a
chromosome and fuses it to another chromosome
Which of the following regarding genome wide gene expression screens
is false? - ANSWERS-The hybridization probes bind to proteins within
the cell
Which of the following is defined as large numbers of chromosomal
rearrangements are generated in what appear to be single catastrophic
events? - ANSWERS-Chromothripsis
END OF
PAGE
2
