A+
RN Adult Medical-Surgical Nursing Review
Module 11.0 - ATI CMS Test Bank 2026/2027 |
250 Q&A
LATEST 2026/2027 | 100% VERIFIED ANSWERS WITH RATIONALE |
GRADED A+ | 250 REAL ATI CMS-STYLE QUESTIONS | RN MEDICAL-
SURGICAL NURSING
Verified Questions, Answers and Rationales
250 ATI CMS Exam-Style Questions · Guaranteed Pass
Format: Q&A plus Rationales plus Why Grade: A+ / Guaranteed Pass
Wrong
Questions: 250 ATI CMS-Style Questions Access: Instant PDF Download
100% verified correct answers with detailed Why Wrong sections for every incorrect option
medical-surgical rationales
Covers all 14 ATI CMS content units: foundations, Includes NGN clinical judgment scenarios and
neurosensory, respiratory, cardiovascular, evidence-based practice updates
hematologic, fluid/electrolyte, GI, renal,
reproductive, musculoskeletal, integumentary,
endocrine, immune, perioperative
Addresses pharmacology, client education, safety, Based on ATI RN Adult Medical-Surgical Nursing
and priority nursing interventions Review Module Edition 11.0 Content Mastery
Series
High-yield content for nursing students preparing Instant PDF download – start studying
for ATI CMS and NCLEX-RN immediately
Description
This RN Adult Medical-Surgical Nursing Review Module Edition 11.0 - ATI Content Mastery Series
Test Bank 2026/2027 is designed to help you master the essential medical-surgical nursing
,concepts needed to excel in your ATI CMS exam. Inside, you will find 250 practice questions that
closely mirror the actual ATI exam in style, difficulty, and content distribution. We cover all 14
content units: foundations of nursing care for adult clients, neurosensory disorders, respiratory
disorders, cardiovascular disorders, hematologic disorders, fluid/electrolyte/acid-base imbalances,
gastrointestinal disorders, renal disorders, reproductive disorders, musculoskeletal disorders,
integumentary disorders, endocrine disorders, immune system and connective tissue disorders,
and nursing care of perioperative clients. Each question comes with a 100% verified correct
answer, a clear medical-surgical rationale that explains the reasoning behind it, and a targeted
Why Wrong section that shows you exactly why the other choices are incorrect. Updated for the
latest testing cycle, this A+ graded review will give you the confidence you need to pass your ATI
CMS exam on the very first attempt.
Abstract
This document provides a complete review of the RN Adult Medical-Surgical Nursing Content
Mastery Series (ATI CMS) exam through 250 realistic exam-style questions covering all 14 content
units. Each question is paired with a 100% verified correct answer, a detailed medical-surgical
rationale, and a thorough Why Wrong breakdown. Updated for the latest testing cycle, this study
guide is designed to help nursing students achieve a high score and pass the ATI CMS exam with
guaranteed accuracy.
Content Area Questions Key Topics Weight
Foundations of Nursing 1 – 25 Patient safety, infection control, pain 10%
Care management, palliative care, ethical/legal
issues.
Neurosensory & 26 – 60 Stroke, seizures, head injuries, COPD, asthma, 14%
Respiratory Disorders pneumonia, TB, ARDS, mechanical ventilation.
Cardiovascular & 61 – 100 MI, heart failure, dysrhythmias, hypertension, 16%
Hematologic Disorders DIC, anemia, leukemia, hemophilia,
anticoagulation.
Fluid/Electrolyte & 101 – 140 Fluid imbalances, acid-base, GI bleeding, ulcers, 16%
Gastrointestinal Disorders IBD, hepatitis, cirrhosis, pancreatitis, nutrition.
Renal, Reproductive & 141 – 175 AKI, CKD, dialysis, UTIs, prostate disorders, 14%
Musculoskeletal Disorders fractures, arthritis, osteoporosis, casts.
, Content Area Questions Key Topics Weight
Integumentary, Endocrine 176 – 215 Pressure injuries, burns, diabetes, thyroid 16%
& Immune Disorders disorders, adrenal disorders, HIV/AIDS,
autoimmune disorders.
Perioperative Care & 216 – 250 Pre-op, intra-op, post-op care, wound healing, 14%
Comprehensive Review complications, pain management, discharge.
Pass your ATI RN Adult Medical-Surgical Nursing CMS Exam on your first attempt with
this comprehensive, A+ graded review.
250 ATI CMS-Style Questions with Verified
Answers and Rationales
Qn 1. A nurse is preparing to obtain a skin specimen from a client who has a suspected
herpes infection. Which of the following actions should the nurse take? (Select all that
apply.)
A A. Scrape the site with a wooden tongue depressor
B B. Use a razor to cut the scabbed area to obtain the specimen
C C. Use a cotton-tipped applicator to obtain fluid from the lesion
D D. Place specimen in a KOH solution tube
E E. Place specimen tube on ice after obtaining sample
Correct Answer: C. Use a cotton-tipped applicator to obtain fluid from the lesion
Rationale: For suspected herpes lesions, the nurse should use a cotton-tipped applicator to
obtain fluid from the unroofed vesicle and place the specimen tube on ice. A Tzanck smear
is used to confirm viral infections. Scraping with a wooden tongue depressor and KOH are
used for fungal infections. Razors should not be used to cut lesions.
Why Wrong:
A. A: Scraping with a wooden tongue depressor is used for fungal specimens, not viral.
B. B: Razors should not be used to cut scabbed areas; this can cause bleeding.
C. D: KOH is used for fungal specimens, not viral.
, References: RN Adult Medical Surgical Nursing Review Module Edition 11.0 - ATI Content
Mastery Series; Lewis's Medical-Surgical Nursing; Ignatavicius's Medical-Surgical Nursing:
Concepts for Clinical Judgment and Collaborative Care.
Qn 2. A nurse administered midazolam IV bolus to a client before a procedure. The
client's blood pressure is 86/40 mmHg, HR is 134/min. Which of the following IV
medications should the nurse administer?
A A. Naloxone
B B. Morphine
C C. Flumazenil
D D. Atropine
Correct Answer: C. Flumazenil
Rationale: Midazolam is a benzodiazepine. Flumazenil is the reversal agent for
benzodiazepines. Hypotension and tachycardia are signs of benzodiazepine toxicity.
Naloxone reverses opioids, morphine would worsen hypotension, and atropine treats
bradycardia.
Why Wrong:
A. A: Naloxone is the reversal agent for opioids, not benzodiazepines.
B. B: Morphine would worsen hypotension and respiratory depression.
C. D: Atropine treats bradycardia, but the client has tachycardia.
References: RN Adult Medical Surgical Nursing Review Module Edition 11.0 - ATI Content
Mastery Series; Lewis's Medical-Surgical Nursing; Ignatavicius's Medical-Surgical Nursing:
Concepts for Clinical Judgment and Collaborative Care.
Qn 3. A nurse at a clinic is talking with a client who has cancer and takes extended-
release opioids twice daily. The client reports an increase in localized, achy pain over the
last few days. How should the nurse document this increase in pain?
A A. Phantom limb pain
B B. Mixed pain
C C. Breakthrough pain
D D. Neuropathic pain
Correct Answer: C. Breakthrough pain
Rationale: Breakthrough pain is a transient increase in pain that occurs despite around-
the-clock opioid therapy. It is common in cancer patients. Phantom limb pain occurs after
RN Adult Medical-Surgical Nursing Review
Module 11.0 - ATI CMS Test Bank 2026/2027 |
250 Q&A
LATEST 2026/2027 | 100% VERIFIED ANSWERS WITH RATIONALE |
GRADED A+ | 250 REAL ATI CMS-STYLE QUESTIONS | RN MEDICAL-
SURGICAL NURSING
Verified Questions, Answers and Rationales
250 ATI CMS Exam-Style Questions · Guaranteed Pass
Format: Q&A plus Rationales plus Why Grade: A+ / Guaranteed Pass
Wrong
Questions: 250 ATI CMS-Style Questions Access: Instant PDF Download
100% verified correct answers with detailed Why Wrong sections for every incorrect option
medical-surgical rationales
Covers all 14 ATI CMS content units: foundations, Includes NGN clinical judgment scenarios and
neurosensory, respiratory, cardiovascular, evidence-based practice updates
hematologic, fluid/electrolyte, GI, renal,
reproductive, musculoskeletal, integumentary,
endocrine, immune, perioperative
Addresses pharmacology, client education, safety, Based on ATI RN Adult Medical-Surgical Nursing
and priority nursing interventions Review Module Edition 11.0 Content Mastery
Series
High-yield content for nursing students preparing Instant PDF download – start studying
for ATI CMS and NCLEX-RN immediately
Description
This RN Adult Medical-Surgical Nursing Review Module Edition 11.0 - ATI Content Mastery Series
Test Bank 2026/2027 is designed to help you master the essential medical-surgical nursing
,concepts needed to excel in your ATI CMS exam. Inside, you will find 250 practice questions that
closely mirror the actual ATI exam in style, difficulty, and content distribution. We cover all 14
content units: foundations of nursing care for adult clients, neurosensory disorders, respiratory
disorders, cardiovascular disorders, hematologic disorders, fluid/electrolyte/acid-base imbalances,
gastrointestinal disorders, renal disorders, reproductive disorders, musculoskeletal disorders,
integumentary disorders, endocrine disorders, immune system and connective tissue disorders,
and nursing care of perioperative clients. Each question comes with a 100% verified correct
answer, a clear medical-surgical rationale that explains the reasoning behind it, and a targeted
Why Wrong section that shows you exactly why the other choices are incorrect. Updated for the
latest testing cycle, this A+ graded review will give you the confidence you need to pass your ATI
CMS exam on the very first attempt.
Abstract
This document provides a complete review of the RN Adult Medical-Surgical Nursing Content
Mastery Series (ATI CMS) exam through 250 realistic exam-style questions covering all 14 content
units. Each question is paired with a 100% verified correct answer, a detailed medical-surgical
rationale, and a thorough Why Wrong breakdown. Updated for the latest testing cycle, this study
guide is designed to help nursing students achieve a high score and pass the ATI CMS exam with
guaranteed accuracy.
Content Area Questions Key Topics Weight
Foundations of Nursing 1 – 25 Patient safety, infection control, pain 10%
Care management, palliative care, ethical/legal
issues.
Neurosensory & 26 – 60 Stroke, seizures, head injuries, COPD, asthma, 14%
Respiratory Disorders pneumonia, TB, ARDS, mechanical ventilation.
Cardiovascular & 61 – 100 MI, heart failure, dysrhythmias, hypertension, 16%
Hematologic Disorders DIC, anemia, leukemia, hemophilia,
anticoagulation.
Fluid/Electrolyte & 101 – 140 Fluid imbalances, acid-base, GI bleeding, ulcers, 16%
Gastrointestinal Disorders IBD, hepatitis, cirrhosis, pancreatitis, nutrition.
Renal, Reproductive & 141 – 175 AKI, CKD, dialysis, UTIs, prostate disorders, 14%
Musculoskeletal Disorders fractures, arthritis, osteoporosis, casts.
, Content Area Questions Key Topics Weight
Integumentary, Endocrine 176 – 215 Pressure injuries, burns, diabetes, thyroid 16%
& Immune Disorders disorders, adrenal disorders, HIV/AIDS,
autoimmune disorders.
Perioperative Care & 216 – 250 Pre-op, intra-op, post-op care, wound healing, 14%
Comprehensive Review complications, pain management, discharge.
Pass your ATI RN Adult Medical-Surgical Nursing CMS Exam on your first attempt with
this comprehensive, A+ graded review.
250 ATI CMS-Style Questions with Verified
Answers and Rationales
Qn 1. A nurse is preparing to obtain a skin specimen from a client who has a suspected
herpes infection. Which of the following actions should the nurse take? (Select all that
apply.)
A A. Scrape the site with a wooden tongue depressor
B B. Use a razor to cut the scabbed area to obtain the specimen
C C. Use a cotton-tipped applicator to obtain fluid from the lesion
D D. Place specimen in a KOH solution tube
E E. Place specimen tube on ice after obtaining sample
Correct Answer: C. Use a cotton-tipped applicator to obtain fluid from the lesion
Rationale: For suspected herpes lesions, the nurse should use a cotton-tipped applicator to
obtain fluid from the unroofed vesicle and place the specimen tube on ice. A Tzanck smear
is used to confirm viral infections. Scraping with a wooden tongue depressor and KOH are
used for fungal infections. Razors should not be used to cut lesions.
Why Wrong:
A. A: Scraping with a wooden tongue depressor is used for fungal specimens, not viral.
B. B: Razors should not be used to cut scabbed areas; this can cause bleeding.
C. D: KOH is used for fungal specimens, not viral.
, References: RN Adult Medical Surgical Nursing Review Module Edition 11.0 - ATI Content
Mastery Series; Lewis's Medical-Surgical Nursing; Ignatavicius's Medical-Surgical Nursing:
Concepts for Clinical Judgment and Collaborative Care.
Qn 2. A nurse administered midazolam IV bolus to a client before a procedure. The
client's blood pressure is 86/40 mmHg, HR is 134/min. Which of the following IV
medications should the nurse administer?
A A. Naloxone
B B. Morphine
C C. Flumazenil
D D. Atropine
Correct Answer: C. Flumazenil
Rationale: Midazolam is a benzodiazepine. Flumazenil is the reversal agent for
benzodiazepines. Hypotension and tachycardia are signs of benzodiazepine toxicity.
Naloxone reverses opioids, morphine would worsen hypotension, and atropine treats
bradycardia.
Why Wrong:
A. A: Naloxone is the reversal agent for opioids, not benzodiazepines.
B. B: Morphine would worsen hypotension and respiratory depression.
C. D: Atropine treats bradycardia, but the client has tachycardia.
References: RN Adult Medical Surgical Nursing Review Module Edition 11.0 - ATI Content
Mastery Series; Lewis's Medical-Surgical Nursing; Ignatavicius's Medical-Surgical Nursing:
Concepts for Clinical Judgment and Collaborative Care.
Qn 3. A nurse at a clinic is talking with a client who has cancer and takes extended-
release opioids twice daily. The client reports an increase in localized, achy pain over the
last few days. How should the nurse document this increase in pain?
A A. Phantom limb pain
B B. Mixed pain
C C. Breakthrough pain
D D. Neuropathic pain
Correct Answer: C. Breakthrough pain
Rationale: Breakthrough pain is a transient increase in pain that occurs despite around-
the-clock opioid therapy. It is common in cancer patients. Phantom limb pain occurs after
