NR 546 Midterm Exam Advanced
Pathophysiology Questions and Answers
1. Which of the following data is most accurate in determining a
treatment plan for a patient who presents with depression?: The patient states
that they are experiencing feelings of sadness, insomnia, and lack of appetite
2. Informed Consent: clients have the right to receive enough information to make decisions
about their treatment. They must also be informed about the potential risks associated with medication.
Clients have the right to refuse treatment and cannot be forcibly medicated in non-emergencies.
3. Which lobe is responsible for movement and intelligence and can
result in
personality changes if damaged?: Frontal Lobe
4. The PMHNP wants to prescribe olanzipine for a client with
depression. How- ever, the client currently takes amiodarone for
chronic atrial fibrillation. What does the PMHNP need to do to
establish efficiency of this medication?: Decrease the dosage of olanzipine
Amiodarone is a CYP450 inhibitor which means it will stop/slow down the olanzapine from metabolizing in
the body. Therefore, the olanzapine is at risk for building up in the client's system rather than being
metabolized and secreted.
,5. What NTM is responsible for a patient's diagnosis of Parkinson's?:
Dopamine
dopamine affects balance and coordination, low levels are found in Parkinson's.
6. A surgical patient is post-op after a hernia repair. The patient is
given opioids in the OR and now has a shallow respiratory rate,
pinpoint pupils, and is unresponsive to verbal stimulation. The
PMHNP prescribed naloxone to reverse the effects of the opioids.
Where does Naloxone fall on the agonist spectrum?: Antagonist
7. Medications for schizophrenia target which main neurotransmitter?:
Dopamine
dopamine causes negative and positive symptoms of schizophrenia, medication block dopamine to
reduce these symptoms
8. first generation
antipsychotics improve symptoms, and there is a
higher risk of developing .: positive, hyperprolactinemia
9. Which medication is a good option for a patient with schizophrenia
who also suffers from insomnia?: Olanzapine
, Olanzapine is the best tolerated antipsychotic
10. What brain region is responsible for speech comprehension?:
Wernicke's Area
11. Which neurotransmitter may be responsible for a client's
symptoms of de- pression? SATA
a. increased level of ACH
b. decreased levels of NE
c. increased levels of 5HT
d. decreased levels of histamine
e. increased levels of glutamate: a. increased levels of ACH
b. decreased levels of NE
d. decreased levels of histamine
12. Which pathway is associated with hyperprolactemia?:
Tuberoinfundibular
13. True or False: Sulfonamides are an example of CYP450
inducer.: False, they are inhibitors
14. GABA: chief inhibitory neurotransmitter and targeted by BZOs
Pathophysiology Questions and Answers
1. Which of the following data is most accurate in determining a
treatment plan for a patient who presents with depression?: The patient states
that they are experiencing feelings of sadness, insomnia, and lack of appetite
2. Informed Consent: clients have the right to receive enough information to make decisions
about their treatment. They must also be informed about the potential risks associated with medication.
Clients have the right to refuse treatment and cannot be forcibly medicated in non-emergencies.
3. Which lobe is responsible for movement and intelligence and can
result in
personality changes if damaged?: Frontal Lobe
4. The PMHNP wants to prescribe olanzipine for a client with
depression. How- ever, the client currently takes amiodarone for
chronic atrial fibrillation. What does the PMHNP need to do to
establish efficiency of this medication?: Decrease the dosage of olanzipine
Amiodarone is a CYP450 inhibitor which means it will stop/slow down the olanzapine from metabolizing in
the body. Therefore, the olanzapine is at risk for building up in the client's system rather than being
metabolized and secreted.
,5. What NTM is responsible for a patient's diagnosis of Parkinson's?:
Dopamine
dopamine affects balance and coordination, low levels are found in Parkinson's.
6. A surgical patient is post-op after a hernia repair. The patient is
given opioids in the OR and now has a shallow respiratory rate,
pinpoint pupils, and is unresponsive to verbal stimulation. The
PMHNP prescribed naloxone to reverse the effects of the opioids.
Where does Naloxone fall on the agonist spectrum?: Antagonist
7. Medications for schizophrenia target which main neurotransmitter?:
Dopamine
dopamine causes negative and positive symptoms of schizophrenia, medication block dopamine to
reduce these symptoms
8. first generation
antipsychotics improve symptoms, and there is a
higher risk of developing .: positive, hyperprolactinemia
9. Which medication is a good option for a patient with schizophrenia
who also suffers from insomnia?: Olanzapine
, Olanzapine is the best tolerated antipsychotic
10. What brain region is responsible for speech comprehension?:
Wernicke's Area
11. Which neurotransmitter may be responsible for a client's
symptoms of de- pression? SATA
a. increased level of ACH
b. decreased levels of NE
c. increased levels of 5HT
d. decreased levels of histamine
e. increased levels of glutamate: a. increased levels of ACH
b. decreased levels of NE
d. decreased levels of histamine
12. Which pathway is associated with hyperprolactemia?:
Tuberoinfundibular
13. True or False: Sulfonamides are an example of CYP450
inducer.: False, they are inhibitors
14. GABA: chief inhibitory neurotransmitter and targeted by BZOs
