k% A nswer ke
(Test #3)
Midterm Exam II
CHEM 2100
March 4, 2026
Please carefully read these instructions
* Please fill out your last name, first name, and student number on the student answer sheet.
* There is a total of 22 questions. You need to answer any 20 to get full credit, and
answering all of them gives you extra credit.
* You can write on the question set; however, it will not be graded.
e Calculators and cell phones are not allowed.
* The periodic table and pka table have been included at the end of the question set.
* There is ZERO TOLERANCE FOR CHEATING.
Question type: Multiple Choice
1. Consider the molecule afenolol (a 3 blocker used to treat hypertension). Which of the
following lists the correct functional groups present in atenolol?
o Ly
OH
atenolol (used to treat high blood pressure)
A) Primary alcohol, amide, primary amine, aromatic, ether
B) Secondary alcohol, amide, secondary amine, aromatic, ester
C) Secondary alcohol, amide, primary amine, aromatic, ether
Secondary alcohol, amide, secondary amine, aromatic, ether
D) Primary alcohol, amide, secondary amine, aromatic, ether
2. Identify the conjugate acid of CH3-O-CH3,
® ® o He o
CHy-O-CHy CHy-O-CH, CHa-0-CHy CHy-O-CHy CHy-O
| I i v v
Al
B)II
C) I
vV
E)V
, Hkk
3. For the following reaction identify the acid, base, conjugate acid and conjugate base.
/\ + NaOH —= H,0 + 7NO Ne®
H
I 1l v
A) I =base; II = acid; III = conjugate base; IV = conjugate acid
B) I = acid; II = base; I1I = conjugate base; IV = conjugate acid
C) I = base; II = acid; III = conjugate acid; IV = conjugate base
D)1 = acid; II = base; III = conjugate acid; IV = conjugate base
) I = base; II = base; III = conjugate acid; IV = conjugate acid
4. For the following acid-base reaction, identify the correct curved arrow mechanism.
H H
®
@—N\—H NS —— @—Ni + Hfi/\
W H
® H T N
| NCH + NS
O T
H
H
@ N
H RN YV
M @—r{% FOHNTS
H
H
O™
v ON’\—(E +OHNTS
H
@)
H N\
v N2H T+ HNTS
’ H
Al
I
opill
D)IV
E)V
(Test #3)
Midterm Exam II
CHEM 2100
March 4, 2026
Please carefully read these instructions
* Please fill out your last name, first name, and student number on the student answer sheet.
* There is a total of 22 questions. You need to answer any 20 to get full credit, and
answering all of them gives you extra credit.
* You can write on the question set; however, it will not be graded.
e Calculators and cell phones are not allowed.
* The periodic table and pka table have been included at the end of the question set.
* There is ZERO TOLERANCE FOR CHEATING.
Question type: Multiple Choice
1. Consider the molecule afenolol (a 3 blocker used to treat hypertension). Which of the
following lists the correct functional groups present in atenolol?
o Ly
OH
atenolol (used to treat high blood pressure)
A) Primary alcohol, amide, primary amine, aromatic, ether
B) Secondary alcohol, amide, secondary amine, aromatic, ester
C) Secondary alcohol, amide, primary amine, aromatic, ether
Secondary alcohol, amide, secondary amine, aromatic, ether
D) Primary alcohol, amide, secondary amine, aromatic, ether
2. Identify the conjugate acid of CH3-O-CH3,
® ® o He o
CHy-O-CHy CHy-O-CH, CHa-0-CHy CHy-O-CHy CHy-O
| I i v v
Al
B)II
C) I
vV
E)V
, Hkk
3. For the following reaction identify the acid, base, conjugate acid and conjugate base.
/\ + NaOH —= H,0 + 7NO Ne®
H
I 1l v
A) I =base; II = acid; III = conjugate base; IV = conjugate acid
B) I = acid; II = base; I1I = conjugate base; IV = conjugate acid
C) I = base; II = acid; III = conjugate acid; IV = conjugate base
D)1 = acid; II = base; III = conjugate acid; IV = conjugate base
) I = base; II = base; III = conjugate acid; IV = conjugate acid
4. For the following acid-base reaction, identify the correct curved arrow mechanism.
H H
®
@—N\—H NS —— @—Ni + Hfi/\
W H
® H T N
| NCH + NS
O T
H
H
@ N
H RN YV
M @—r{% FOHNTS
H
H
O™
v ON’\—(E +OHNTS
H
@)
H N\
v N2H T+ HNTS
’ H
Al
I
opill
D)IV
E)V
