NURS 5334
NURS 5334 FINAL EXAM GRADED A+
Prescribing basics - correct answer Prescribing is regulated by
state BON
Proper RX - correct answer Providers name and address,
Telephone
DEA
Pt name/DOB/Addres
Name of Drug, strength, SIG(directions) with
indication/Route and frequency, Quantity and signature.
,NURS 5334
Drug Schedules: Most addictive to least - correct answer 1:
Heroin,LSD, MJ
2: hydrocodone, cocaine, Methamphetamine,
methadone, oxycodone, meperidine, fentanyl, adderall,
ritalin
3: codeine, ketamine, testosterone
4: xanax, valium, soma, ambient, tramadol
5: antidiarrheal, antitussives, lomotil, lyrica
Pharmicodyamics - correct answer The effects of drug on the
body. Receptors are large molecules usually proteins, that
interact and mediate the action of drugs
agonist - correct answer produce receptor stimulation and a
conformational change every time they bind. Do not
need all available receptors to produce a maximum
response
Partial agonist - correct answer drugs that have properties in
b/w those of full agonist and antagonist. They bind to
,NURS 5334
receptors but when they occupy the receptor sites, they
stimulate only some of the receptors.
antagonist - correct answer drugs with affinity for a receptor
but with no intrinsic activity. Affinity allows the
antagonist to bind to receptors, but lack of intrinsic
activity prevents the bound antagonist from causing
receptor activation. The block action of drugs (ex.
Narcan)
Bioavailabity - correct answer % of administered dosage of the
drug that survives the first pass through the liver and
reaches the blood stream
half life - correct answer Time required for the amount of a
drug in the body to decline by 50%, drugs with shorter
half lives must be administer frequently. 4.5-5.5 times the
half life to get steady state and to be limited from the
body
what the body does to the drug - correct answer absorption,
distribution, metabolism, excretion
, NURS 5334
Distribution - correct answer movement of absorbed drug in
bodily fluids throughout the body to target tissue.
Properties affecting: lipid/water solubility, PH affects
ionization of drug, protein binding, size of molecule
(smaller molecules are more able to diffuse)
Tissue: fat, bone, blood/brain barrier (only lipid soluble
will pass), placental barrier (many drugs can pass)
Protein binding - correct answer unbound drug is free which is
active, crosses membrane. Low plasma proteins result in
more free drug. Competition: when 2 highly bound drugs
are given it increases the level of both drugs
Metabolism - correct answer take place in the liver mostly.
Chemical change of a drug structure to:
Enhance excretion, inactivate the drug, increase
therapeutic action, active a prodrug (inactive until
metabolized in the body into the active compound, ex:
levodopa), increase or decrease toxicity
NURS 5334 FINAL EXAM GRADED A+
Prescribing basics - correct answer Prescribing is regulated by
state BON
Proper RX - correct answer Providers name and address,
Telephone
DEA
Pt name/DOB/Addres
Name of Drug, strength, SIG(directions) with
indication/Route and frequency, Quantity and signature.
,NURS 5334
Drug Schedules: Most addictive to least - correct answer 1:
Heroin,LSD, MJ
2: hydrocodone, cocaine, Methamphetamine,
methadone, oxycodone, meperidine, fentanyl, adderall,
ritalin
3: codeine, ketamine, testosterone
4: xanax, valium, soma, ambient, tramadol
5: antidiarrheal, antitussives, lomotil, lyrica
Pharmicodyamics - correct answer The effects of drug on the
body. Receptors are large molecules usually proteins, that
interact and mediate the action of drugs
agonist - correct answer produce receptor stimulation and a
conformational change every time they bind. Do not
need all available receptors to produce a maximum
response
Partial agonist - correct answer drugs that have properties in
b/w those of full agonist and antagonist. They bind to
,NURS 5334
receptors but when they occupy the receptor sites, they
stimulate only some of the receptors.
antagonist - correct answer drugs with affinity for a receptor
but with no intrinsic activity. Affinity allows the
antagonist to bind to receptors, but lack of intrinsic
activity prevents the bound antagonist from causing
receptor activation. The block action of drugs (ex.
Narcan)
Bioavailabity - correct answer % of administered dosage of the
drug that survives the first pass through the liver and
reaches the blood stream
half life - correct answer Time required for the amount of a
drug in the body to decline by 50%, drugs with shorter
half lives must be administer frequently. 4.5-5.5 times the
half life to get steady state and to be limited from the
body
what the body does to the drug - correct answer absorption,
distribution, metabolism, excretion
, NURS 5334
Distribution - correct answer movement of absorbed drug in
bodily fluids throughout the body to target tissue.
Properties affecting: lipid/water solubility, PH affects
ionization of drug, protein binding, size of molecule
(smaller molecules are more able to diffuse)
Tissue: fat, bone, blood/brain barrier (only lipid soluble
will pass), placental barrier (many drugs can pass)
Protein binding - correct answer unbound drug is free which is
active, crosses membrane. Low plasma proteins result in
more free drug. Competition: when 2 highly bound drugs
are given it increases the level of both drugs
Metabolism - correct answer take place in the liver mostly.
Chemical change of a drug structure to:
Enhance excretion, inactivate the drug, increase
therapeutic action, active a prodrug (inactive until
metabolized in the body into the active compound, ex:
levodopa), increase or decrease toxicity
