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1. Which PMHNP domain most directly focuses on psychopharmacology,
neurobiology, and advanced pharmacology?
A. Scientific Foundation
B. Ethics and Legal Principles
C. Psychotherapy and Related Theories
D. Scope of Practice
Correct answer: A.
The Scientific Foundation domain includes advanced pharmacology,
psychopharmacology, neuroanatomy, and related neurobiologic concepts.
These topics support safe prescribing and evidence-based psychiatric
care.
2. Which screening tool is commonly used to assess depressive symptoms in
adults?
A. GAD-7
B. PHQ-9
C. MMSE
D. CIWA-Ar
Correct answer: B.
The PHQ-9 is widely used to screen for and measure the severity of
depression. It helps guide diagnosis and monitor treatment response.
,3. Which screening tool is commonly used to assess generalized anxiety
symptoms?
A. GAD-7
B. PHQ-9
C. MoCA
D. AUDIT
Correct answer: A.
The GAD-7 is a common tool for assessing anxiety symptoms and severity.
It is often used in both primary care and psychiatric settings.
4. A patient reports decreased need for sleep, grandiosity, pressured speech,
and risky spending. What diagnosis is most likely?
A. Major depressive disorder
B. Bipolar I disorder, manic episode
C. Generalized anxiety disorder
D. PTSD
Correct answer: B.
These are classic manic symptoms and strongly suggest bipolar I disorder
with a manic episode. The combination of elevated mood, decreased sleep,
and impulsive behavior is highly characteristic.
5. Which medication class is considered first-line for many patients with
major depressive disorder?
A. SSRIs
B. Typical antipsychotics
C. Benzodiazepines
D. Stimulants
Correct answer: A.
, Selective serotonin reuptake inhibitors are commonly used as first-line
treatment for depression. They are effective and generally well tolerated.
6. Which antidepressant carries a risk of serotonin syndrome when combined
with other serotonergic agents?
A. Sertraline
B. Haloperidol
C. Lithium
D. Valproate
Correct answer: A.
Sertraline is an SSRI and can contribute to serotonin syndrome when
combined with other serotonergic medications. Recognizing this
interaction is important for safe prescribing.
7. A patient taking haloperidol develops muscle rigidity, fever, and autonomic
instability. What serious condition should be suspected?
A. Serotonin syndrome
B. Neuroleptic malignant syndrome
C. Panic attack
D. Akathisia
Correct answer: B.
Neuroleptic malignant syndrome is a life-threatening reaction associated
with antipsychotic use. It typically presents with rigidity, fever, and
autonomic instability.
8. Which symptom is most consistent with schizophrenia?
A. One week of worry about finances
B. Auditory hallucinations and disorganized thought
C. Fear of flying only
D. Brief sadness after an argument
, Correct answer: B.
Schizophrenia often involves hallucinations, delusions, and disorganized
thinking. Auditory hallucinations are especially common.
9. What is the first priority when a patient expresses suicidal intent with a
plan?
A. Teach relaxation techniques
B. Assess immediate safety and risk
C. Schedule a routine follow-up in two weeks
D. Focus only on sleep hygiene
Correct answer: B.
Immediate suicide risk assessment and safety planning are the priority.
The clinician must determine imminent danger and act to protect the
patient.
10. Which medication level is commonly monitored in patients taking
lithium?
A. INR
B. Serum lithium level
C. Troponin
D. Amylase only
Correct answer: B.
Lithium has a narrow therapeutic index, so serum levels must be
monitored regularly. Toxicity can occur if levels rise too high.
11. Which side effect is commonly associated with second-generation
antipsychotics?
A. Weight gain and metabolic changes
B. Hearing loss
C. Hair color change