PAT 202: WEEK ONE (1): CARDIOVASCULAR PHARMACOLOGY ASYNCHRONOUS PPT (THINK HTN, MI, HF, ANGINA, &/STROKE): PART TWO

PAT 202: WEEK ONE (1): CARDIOVASCULAR
PHARMACOLOGY ASYNCHRONOUS PPT (THINK HTN,
MI, HF, ANGINA, &/STROKE): PART TWO


- CARDIOVASCULAR DISEASE PHARMACOLOGY-

CLASS ONE: ANALGESICS
medication: morphine

what are some indications for use

think specifically for cdv diseases - Answers - remember goal 5 of cardio pharm therapy
was reducing pain and anxiety

morphine indications include
a. acute MI pain
b. chronic pain
c. relieve SOB
d. with HF can relieve PE

- CARDIOVASCULAR DISEASE PHARMACOLOGY-

CLASS ONE: ANALGESICS
medication: morphine

t or f
morphine is indicated for sob and HF with PE - Answers - true

- CARDIOVASCULAR DISEASE PHARMACOLOGY-

CLASS ONE: ANALGESICS
medication: morphine

MOA
(specifically the mu and kappa moa) - Answers - binds with mu and kappa receptors in
brain and dorsal horn of spinal cord

mimicks our bodies own opioids
endorphins and enkephalis

- CARDIOVASCULAR DISEASE PHARMACOLOGY-

CLASS ONE: ANALGESICS

,medication: morphine

function of mu receptor - Answers - MU: found mostly in the brainstem and medial
thalamys: cause RD, eurphoria, sedation, and decreased GI activity

- CARDIOVASCULAR DISEASE PHARMACOLOGY-

CLASS ONE: ANALGESICS
medication: morphine

function of kappa receptor - Answers - kappa: found in the limbic system, brain stem,
and spinal cord: spinal analgesia, sedation, dyspnea, dependence, dysphoria, and RD

When opioids attach (bind) to the receptors, the interaction triggers a series of chemical
changes within and between neurons that lead to feelings of pleasure and pain relief.

- CARDIOVASCULAR DISEASE PHARMACOLOGY-

CLASS ONE: ANALGESICS
medication: morphine

moa specifically the one r/t to alpha receptors - Answers - decrease the responsiveness
of alpha adrenergic receptors

causing peripheral vasodilation

alpha-adrenergic receptors - Answers - Portions of the nervous system that, when
stimulated, can cause constriction of blood vessels.

alpha-adrenergic receptors - Answers - Receptors to norepinephrine that generally
produce an excitatory response

beta-adrenergic receptors - Answers - Portions of the nervous system that, when
stimulated, can cause an increase in the force of contraction of the heart, an increased
heart rate, and bronchial dilation.

alpha receptors cause vaso cxn
beta receptors cause vaso dilation
T OR F - Answers - TRUE

- CARDIOVASCULAR DISEASE PHARMACOLOGY-

CLASS ONE: ANALGESICS
medication: morphine

DESIRED EFFECTS - Answers - profound analgesa

, sedation
eurphoria
less anxiety and fear

less CO by
vasodilation--> less pvr and less volume---> less preload and less afterload---> less sv--
-: less co

- CARDIOVASCULAR DISEASE PHARMACOLOGY-

CLASS ONE: ANALGESICS
medication: morphine

adverse effects - Answers - CNS depression
RD
cardiac arrest

dysphoria (unease, depresssion and anxiety)

hallucinations dizziness constiatipn anuse

itching sensation (pruritus)

- CARDIOVASCULAR DISEASE PHARMACOLOGY-

CLASS ONE: ANALGESICS
medication: morphine

T OR F
itching sensation
cardiac arrest
hallucations
depression
anxiety are some adverse effects of morphine - Answers - TRUE

- CARDIOVASCULAR DISEASE PHARMACOLOGY-

CLASS ONE: ANALGESICS
medication: morphine

morphine stimulated the cardiac musle
morphine causes constriction of what - Answers - pupils

- CARDIOVASCULAR DISEASE PHARMACOLOGY-

CLASS ONE: ANALGESICS