HESI LPN-ADN HESI ENTRANCE EXAM PRACTICE | STUDY GUIDE | TESTBANK |
PRACTICE QUESTIONS & ANSWERS | EXAM PREPARATION | COMPREHENSIVE
PRACTICE EXAM | LATEST UPDATE 2026/2027
Examiner:
HESI Admission Assessment (A2) administered by Elsevier for participating nursing
schools
TABLE OF CONTENTS
1. Reading Comprehension
2. Vocabulary and General Knowledge
3. Grammar
4. Basic Mathematics
5. Biology
6. Anatomy and Physiology
7. Chemistry
8. Critical Thinking and Clinical Reasoning
9. Scientific Interpretation
10. Foundational Nursing Readiness
MEDICAL TERMINOLOGY || READING COMPREHENSION || CRITICAL THINKING ||
ANATOMY AND PHYSIOLOGY || BIOLOGY || CHEMISTRY || MATHEMATICS ||
DOSAGE CALCULATIONS || GRAMMAR || VOCABULARY || CLINICAL REASONING
|| SCIENTIFIC LITERACY || EXAM PREPARATION || COMPREHENSIVE REVIEW ||
PROFESSIONAL NURSING READINESS || LATEST UPDATE 2026/2027
QUESTION 1.
A nursing applicant reads the following passage:
"During dehydration, the body conserves water by increasing renal reabsorption. This
process helps maintain blood pressure and supports adequate tissue perfusion despite
reduced fluid intake."
,Which conclusion is best supported by the passage?
A. Dehydration always causes permanent kidney damage.
B. The kidneys contribute to maintaining circulatory stability during dehydration.
C. Water reabsorption lowers blood pressure to prevent edema.
D. Reduced fluid intake immediately eliminates urine production.
🔴 Correct Answer: B. The kidneys contribute to maintaining circulatory stability
during dehydration.
🔵 Explanation: The passage explains that increased renal water reabsorption helps
maintain blood pressure and tissue perfusion during dehydration. It does not state
that dehydration permanently damages the kidneys, completely stops urine
production, or lowers blood pressure.
QUESTION 2.
A student mixes 250 mL of saline with 750 mL of sterile water. What is the total
volume?
A. 900 mL
B. 1,000 mL
C. 950 mL
D. 1,250 mL
🔴 Correct Answer: B. 1,000 mL
🔵 Explanation: Adding 250 mL and 750 mL results in 1,000 mL. The other values
result from incorrect arithmetic.
QUESTION 3.
Which organelle is primarily responsible for ATP production through aerobic
respiration?
A. Ribosome
B. Lysosome
,C. Mitochondrion
D. Golgi apparatus
🔴 Correct Answer: C. Mitochondrion
🔵 Explanation: Mitochondria generate most cellular ATP through oxidative
phosphorylation. Ribosomes synthesize proteins, lysosomes digest cellular material,
and the Golgi apparatus modifies and packages proteins.
QUESTION 4.
Which sentence is grammatically correct?
A. Neither the instructor nor the students was prepared.
B. Neither the instructor nor the students were prepared.
C. Neither the instructor or the students were prepared.
D. Neither the instructor or the students was prepared.
🔴 Correct Answer: B. Neither the instructor nor the students were prepared.
🔵 Explanation: When subjects are joined by "neither...nor," the verb agrees with the
noun closest to it. Because "students" is plural, the correct verb is "were."
QUESTION 5.
Which blood vessel carries oxygenated blood from the lungs to the heart?
A. Pulmonary artery
B. Superior vena cava
C. Pulmonary vein
D. Inferior vena cava
🔴 Correct Answer: C. Pulmonary vein
🔵 Explanation: Pulmonary veins return oxygen-rich blood from the lungs to the left
atrium. The pulmonary arteries carry deoxygenated blood to the lungs, while the
venae cavae return systemic venous blood to the right atrium.
, QUESTION 6.
A solution has a pH of 2. Compared with a solution having a pH of 4, the first
solution is:
A. 2 times more acidic.
B. 10 times more acidic.
C. 100 times more acidic.
D. 1,000 times more acidic.
🔴 Correct Answer: C. 100 times more acidic.
🔵 Explanation: The pH scale is logarithmic, with each unit representing a tenfold
change in hydrogen ion concentration. A difference of two pH units equals a 100-fold
difference in acidity.
QUESTION 7.
The medical term "bradycardia" refers to:
A. Rapid breathing
B. Slow heart rate
C. High blood pressure
D. Irregular respiration
🔴 Correct Answer: B. Slow heart rate
🔵 Explanation: "Brady-" means slow, and "-cardia" refers to the heart rate. The
remaining options describe different physiological conditions.
QUESTION 8.
A nurse candidate estimates 18% of 250.
A. 35
B. 40
PRACTICE QUESTIONS & ANSWERS | EXAM PREPARATION | COMPREHENSIVE
PRACTICE EXAM | LATEST UPDATE 2026/2027
Examiner:
HESI Admission Assessment (A2) administered by Elsevier for participating nursing
schools
TABLE OF CONTENTS
1. Reading Comprehension
2. Vocabulary and General Knowledge
3. Grammar
4. Basic Mathematics
5. Biology
6. Anatomy and Physiology
7. Chemistry
8. Critical Thinking and Clinical Reasoning
9. Scientific Interpretation
10. Foundational Nursing Readiness
MEDICAL TERMINOLOGY || READING COMPREHENSION || CRITICAL THINKING ||
ANATOMY AND PHYSIOLOGY || BIOLOGY || CHEMISTRY || MATHEMATICS ||
DOSAGE CALCULATIONS || GRAMMAR || VOCABULARY || CLINICAL REASONING
|| SCIENTIFIC LITERACY || EXAM PREPARATION || COMPREHENSIVE REVIEW ||
PROFESSIONAL NURSING READINESS || LATEST UPDATE 2026/2027
QUESTION 1.
A nursing applicant reads the following passage:
"During dehydration, the body conserves water by increasing renal reabsorption. This
process helps maintain blood pressure and supports adequate tissue perfusion despite
reduced fluid intake."
,Which conclusion is best supported by the passage?
A. Dehydration always causes permanent kidney damage.
B. The kidneys contribute to maintaining circulatory stability during dehydration.
C. Water reabsorption lowers blood pressure to prevent edema.
D. Reduced fluid intake immediately eliminates urine production.
🔴 Correct Answer: B. The kidneys contribute to maintaining circulatory stability
during dehydration.
🔵 Explanation: The passage explains that increased renal water reabsorption helps
maintain blood pressure and tissue perfusion during dehydration. It does not state
that dehydration permanently damages the kidneys, completely stops urine
production, or lowers blood pressure.
QUESTION 2.
A student mixes 250 mL of saline with 750 mL of sterile water. What is the total
volume?
A. 900 mL
B. 1,000 mL
C. 950 mL
D. 1,250 mL
🔴 Correct Answer: B. 1,000 mL
🔵 Explanation: Adding 250 mL and 750 mL results in 1,000 mL. The other values
result from incorrect arithmetic.
QUESTION 3.
Which organelle is primarily responsible for ATP production through aerobic
respiration?
A. Ribosome
B. Lysosome
,C. Mitochondrion
D. Golgi apparatus
🔴 Correct Answer: C. Mitochondrion
🔵 Explanation: Mitochondria generate most cellular ATP through oxidative
phosphorylation. Ribosomes synthesize proteins, lysosomes digest cellular material,
and the Golgi apparatus modifies and packages proteins.
QUESTION 4.
Which sentence is grammatically correct?
A. Neither the instructor nor the students was prepared.
B. Neither the instructor nor the students were prepared.
C. Neither the instructor or the students were prepared.
D. Neither the instructor or the students was prepared.
🔴 Correct Answer: B. Neither the instructor nor the students were prepared.
🔵 Explanation: When subjects are joined by "neither...nor," the verb agrees with the
noun closest to it. Because "students" is plural, the correct verb is "were."
QUESTION 5.
Which blood vessel carries oxygenated blood from the lungs to the heart?
A. Pulmonary artery
B. Superior vena cava
C. Pulmonary vein
D. Inferior vena cava
🔴 Correct Answer: C. Pulmonary vein
🔵 Explanation: Pulmonary veins return oxygen-rich blood from the lungs to the left
atrium. The pulmonary arteries carry deoxygenated blood to the lungs, while the
venae cavae return systemic venous blood to the right atrium.
, QUESTION 6.
A solution has a pH of 2. Compared with a solution having a pH of 4, the first
solution is:
A. 2 times more acidic.
B. 10 times more acidic.
C. 100 times more acidic.
D. 1,000 times more acidic.
🔴 Correct Answer: C. 100 times more acidic.
🔵 Explanation: The pH scale is logarithmic, with each unit representing a tenfold
change in hydrogen ion concentration. A difference of two pH units equals a 100-fold
difference in acidity.
QUESTION 7.
The medical term "bradycardia" refers to:
A. Rapid breathing
B. Slow heart rate
C. High blood pressure
D. Irregular respiration
🔴 Correct Answer: B. Slow heart rate
🔵 Explanation: "Brady-" means slow, and "-cardia" refers to the heart rate. The
remaining options describe different physiological conditions.
QUESTION 8.
A nurse candidate estimates 18% of 250.
A. 35
B. 40
