NUR 5461 Hematology Exam Questions and Answers 2026 | Ultimate Exam
Prep & Study Guide
NURS 5461 EXAM 1 - (ANSWER)Exam Coverage
Exam coverage for NURS 5461 Exam 1 includes foundational advanced nursing concepts commonly
introduced in the early part of graduate-level nursing coursework. It focuses on patient assessment,
pathophysiology, pharmacologic considerations, diagnostic reasoning, and management of common
acute and chronic conditions relevant to the course emphasis. The exam also evaluates understanding of
evidence-based practice, interpretation of clinical findings, patient education, prevention strategies, and
safe clinical decision-making. Emphasis is placed on applying advanced nursing knowledge, clinical
reasoning, and patient-centered care principles in preparation for more complex clinical management.
Normocytic Anemia - (ANSWER)Due to hemorrhage or chronic disease. Aplastic anemia. MCV 80-92
Microcytic Anemia - (ANSWER)Iron deficiency, usually due to malabsorption/occult blood loss, or lead
poisoning. MCV <80
Macrocytic Anemia - (ANSWER)Due to folate or vitamin B12 (cobalamin) deficiency (megaloblastic
anemia)/pernicious anemia/liver diseases
Serum Ferritin - (ANSWER)Tests for iron stores. As serum ferritin falls, TIBC rises, and serum iron levels
will eventually fall.
Anemia of Chronic Disease - (ANSWER)Normocytic anemia with ↓ serum iron, ↓ TIBC, and normal iron
stores. Treat with epoetin and give an iron supplement
Schistocytes - (ANSWER)Associated with hemolytic uremia syndrome
Pernicious Anemia - (ANSWER)Macrocytic anemia caused by vitamin B12 deficiency. B12 is essential to
maturation of erythrocytes - low levels will cause the RBC to expand. PPIs and histamine2 blockers can
cause this.
Increased Homocysteine & Methylmalonic Acid Level - (ANSWER)Indicates B12 deficiency
, NUR 5461 Hematology Exam Questions and Answers 2026 | Ultimate Exam
Prep & Study Guide
Increased Homocysteine Levels - (ANSWER)Folate deficiency
Spherocytes - (ANSWER)Appear as spheres, lack central pallor, smaller diameter, indicate immune-
mediated process - can be seen after blood transfusion
Aplastic Anemia - (ANSWER)Failure of bone marrow to produce red blood cells
Low Ferritin - (ANSWER)Iron Deficiency Anemia
Transferrin - (ANSWER)Transports Iron
TIBC (Total Iron Binding Capacity) - (ANSWER)Available transferrin that is left unbound. Reflects iron
levels.
MCHC (Mean Corpuscular Hemoglobin Concentration) - (ANSWER)Concentration of hemoglobin per RBC
Alzheimer's Disease - (ANSWER)Gradual onset with early memory impairment. Most common form of
dementia.
Lewy Body Dementia - (ANSWER)Rapidly progressive dementia seen with Parkinson syndrome. Visual
hallucinations present.
Frontal Lobe Dementia - (ANSWER)Personality impairments before age 60. PDG-PET Scan testing.
PDG-PET Scan - (ANSWER)Measures brain glucose metabolism. Decreased uptake in Alzheimer's.
SSRIs - (ANSWER)Fluoxetine, Paroxetine, Sertraline, Citalopram
Prep & Study Guide
NURS 5461 EXAM 1 - (ANSWER)Exam Coverage
Exam coverage for NURS 5461 Exam 1 includes foundational advanced nursing concepts commonly
introduced in the early part of graduate-level nursing coursework. It focuses on patient assessment,
pathophysiology, pharmacologic considerations, diagnostic reasoning, and management of common
acute and chronic conditions relevant to the course emphasis. The exam also evaluates understanding of
evidence-based practice, interpretation of clinical findings, patient education, prevention strategies, and
safe clinical decision-making. Emphasis is placed on applying advanced nursing knowledge, clinical
reasoning, and patient-centered care principles in preparation for more complex clinical management.
Normocytic Anemia - (ANSWER)Due to hemorrhage or chronic disease. Aplastic anemia. MCV 80-92
Microcytic Anemia - (ANSWER)Iron deficiency, usually due to malabsorption/occult blood loss, or lead
poisoning. MCV <80
Macrocytic Anemia - (ANSWER)Due to folate or vitamin B12 (cobalamin) deficiency (megaloblastic
anemia)/pernicious anemia/liver diseases
Serum Ferritin - (ANSWER)Tests for iron stores. As serum ferritin falls, TIBC rises, and serum iron levels
will eventually fall.
Anemia of Chronic Disease - (ANSWER)Normocytic anemia with ↓ serum iron, ↓ TIBC, and normal iron
stores. Treat with epoetin and give an iron supplement
Schistocytes - (ANSWER)Associated with hemolytic uremia syndrome
Pernicious Anemia - (ANSWER)Macrocytic anemia caused by vitamin B12 deficiency. B12 is essential to
maturation of erythrocytes - low levels will cause the RBC to expand. PPIs and histamine2 blockers can
cause this.
Increased Homocysteine & Methylmalonic Acid Level - (ANSWER)Indicates B12 deficiency
, NUR 5461 Hematology Exam Questions and Answers 2026 | Ultimate Exam
Prep & Study Guide
Increased Homocysteine Levels - (ANSWER)Folate deficiency
Spherocytes - (ANSWER)Appear as spheres, lack central pallor, smaller diameter, indicate immune-
mediated process - can be seen after blood transfusion
Aplastic Anemia - (ANSWER)Failure of bone marrow to produce red blood cells
Low Ferritin - (ANSWER)Iron Deficiency Anemia
Transferrin - (ANSWER)Transports Iron
TIBC (Total Iron Binding Capacity) - (ANSWER)Available transferrin that is left unbound. Reflects iron
levels.
MCHC (Mean Corpuscular Hemoglobin Concentration) - (ANSWER)Concentration of hemoglobin per RBC
Alzheimer's Disease - (ANSWER)Gradual onset with early memory impairment. Most common form of
dementia.
Lewy Body Dementia - (ANSWER)Rapidly progressive dementia seen with Parkinson syndrome. Visual
hallucinations present.
Frontal Lobe Dementia - (ANSWER)Personality impairments before age 60. PDG-PET Scan testing.
PDG-PET Scan - (ANSWER)Measures brain glucose metabolism. Decreased uptake in Alzheimer's.
SSRIs - (ANSWER)Fluoxetine, Paroxetine, Sertraline, Citalopram
