BCH210 Exam/ Study Guide Questions with Correct
Verified Answers – Latest Update 2026/ Rated A+
1. Which ONE of the following amino acids may be linked
covalently to an oligosaccharide via an O-glycosidic bond?
• A. Glc
• B. Tyr
• C. Thr
• D. Asp
Correct Answer: C
Rationale: Threonine (Thr) has a hydroxyl (-OH) group on its side
chain that can form an O-glycosidic bond with an oligosaccharide.
Serine and threonine are the most common amino acids for O-
linked glycosylation. Tyrosine can also be O-glycosylated in some
instances, but Thr is the best answer given the options .
1
,2. Which ONE of the following statements is CORRECT regarding
the polypeptide shown below at pH 7.4?
• A. The polypeptide absorbs UV radiation at 280 nm
• B. The polypeptide has a net positive charge
• C. The polypeptide is primarily hydrophobic
• D. The polypeptide cannot form hydrogen bonds
Correct Answer: A
Rationale: Polypeptides absorb UV radiation at 280 nm primarily
due to the presence of aromatic amino acids (tryptophan and
tyrosine). Tryptophan has the highest molar extinction coefficient at
280 nm .
3. Which ONE of the following functional groups is present and
may be important for mediating binding to a receptor?
• A. Amide
• B. Carboxyl
• C. Hydroxyl
2
, • D. Sulfhydryl
Correct Answer: A
Rationale: Amide groups are common in molecules that bind to
receptors. They can participate in hydrogen bonding with amino
acid side chains in the binding site .
4. Why are D-sugars physiologically relevant and important for
the cell?
• A. They are able to undergo cyclization, while L-sugars only
form linear structures
• B. D-sugars are enantiomers of glucogenic amino acids that
can be used in glycolysis
• C. Enzymes have specificity for binding to the OH in the D
designation position
• D. They are reducing sugars that must first be oxidized
before generating energy
3
, Correct Answer: C
Rationale: Enzymes are stereospecific and have evolved to
recognize and bind to the specific three-dimensional structure of D-
sugars. The orientation of the hydroxyl group at the chiral carbon
farthest from the carbonyl determines the D/L designation .
5. Which ONE of the following amino acids, represented by their
1-letter code, is primarily responsible for binding to a molecule
via hydrogen bonding?
• A. A
• B. G
• C. N
• D. V
Correct Answer: C
Rationale: Asparagine (N) has an amide side chain that can form
hydrogen bonds with ligands or other molecules. This property
makes it important for molecular recognition .
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Verified Answers – Latest Update 2026/ Rated A+
1. Which ONE of the following amino acids may be linked
covalently to an oligosaccharide via an O-glycosidic bond?
• A. Glc
• B. Tyr
• C. Thr
• D. Asp
Correct Answer: C
Rationale: Threonine (Thr) has a hydroxyl (-OH) group on its side
chain that can form an O-glycosidic bond with an oligosaccharide.
Serine and threonine are the most common amino acids for O-
linked glycosylation. Tyrosine can also be O-glycosylated in some
instances, but Thr is the best answer given the options .
1
,2. Which ONE of the following statements is CORRECT regarding
the polypeptide shown below at pH 7.4?
• A. The polypeptide absorbs UV radiation at 280 nm
• B. The polypeptide has a net positive charge
• C. The polypeptide is primarily hydrophobic
• D. The polypeptide cannot form hydrogen bonds
Correct Answer: A
Rationale: Polypeptides absorb UV radiation at 280 nm primarily
due to the presence of aromatic amino acids (tryptophan and
tyrosine). Tryptophan has the highest molar extinction coefficient at
280 nm .
3. Which ONE of the following functional groups is present and
may be important for mediating binding to a receptor?
• A. Amide
• B. Carboxyl
• C. Hydroxyl
2
, • D. Sulfhydryl
Correct Answer: A
Rationale: Amide groups are common in molecules that bind to
receptors. They can participate in hydrogen bonding with amino
acid side chains in the binding site .
4. Why are D-sugars physiologically relevant and important for
the cell?
• A. They are able to undergo cyclization, while L-sugars only
form linear structures
• B. D-sugars are enantiomers of glucogenic amino acids that
can be used in glycolysis
• C. Enzymes have specificity for binding to the OH in the D
designation position
• D. They are reducing sugars that must first be oxidized
before generating energy
3
, Correct Answer: C
Rationale: Enzymes are stereospecific and have evolved to
recognize and bind to the specific three-dimensional structure of D-
sugars. The orientation of the hydroxyl group at the chiral carbon
farthest from the carbonyl determines the D/L designation .
5. Which ONE of the following amino acids, represented by their
1-letter code, is primarily responsible for binding to a molecule
via hydrogen bonding?
• A. A
• B. G
• C. N
• D. V
Correct Answer: C
Rationale: Asparagine (N) has an amide side chain that can form
hydrogen bonds with ligands or other molecules. This property
makes it important for molecular recognition .
4
