Across the Lifespan midterm exam Questions and
Answers- Walden
What are the physiological changes of aging
1. Reduced physiological reserve of most body systems
2.Reduced homeostatic mechanisms that fail to adjust
3. Changes in the sympathetic response
4. Impaired immunological function- infection risk is greater and autoimmune diseases are more
prevalent.
What factors influence lab value interpretation in the older adult
1. physiological changes with aging
2. the prevalence of chronic disease
3. changes in nutritional and fluid intake
4. Lifestyle
What lab values is important
Creatinine clearance, GFR and renal function
What are examples of drugs are eliminated renally
Digoxin, H2 blockers, lithium and water-soluble antibiotics
, What are the two formulas to evaluate the kidney function
The Cockcroft-Gault formula and the Modification of Diet in Renal Disease (MDRD)
What neurological conditions commonly have an initial onset in older age?
Parkinson's, dementia, stroke, and complex partial seizures
What are geriatric syndromes
Diseases that involve multiple systems and have more than one underlying cause
What are the geriatric syndrome giants currently
Frailty, anorexia of aging, sarcopenia and cognitive impairment
What are bimodal presentations of disease
Diseases that can present in a younger age and an older age.
What are examples of bimodal diseases?
Psoriasis, Inflammatory bowel disease, Ulcerative Colitis, Crohn's disease, Hodgkin's lymphoma,
and myasthenia gravis