Cellular and Molecular Immunology, 10th Edition
Complete Test Bank –
Cellular And Molecular Immunology,
10th Edition (Abbas, 2022),
Chapter 1-21 | All Chapters
Page | 1
, Cellular and Molecular Immunology, 10th Edition
Table Of Contents
Chapter 01: Properties And Overview Of Immune Responses .............. 3
Chapter 02: Cells And Tissues Of The Immune System ...................... 6
Chapter 03: Leukocyte Circulation And Migration Into Tissues .......... 10
Chapter 04: Innate Immunity ................................................. 15
Chapter 05: Antibodies And Antigens ........................................ 25
Chapter 06: Antigen Presentation To T Lymphocytes And The Functions
Of Major Histocompatibility Complex Molecules........................... 29
Chapter 07: Immune Receptors And Signal Transduction ................. 38
Chapter 08: Lymphocyte Development And Antigen Receptor Gene
Rearrangement .................................................................. 42
Chapter 09: Activation Of T Lymphocytes................................... 47
Chapter 10: Differentiation And Functions Of Cd4+ Effector T Cells ... 53
Chapter 11: Differentiation And Functions Of Cd8+ Effector T Cells ... 59
Chapter 12: B Cell Activation And Antibody Production .................. 64
Chapter 13: Effector Mechanisms Of Humoral Immunity ................. 72
Chapter 14: Specialized Immunity At Epithelial Barriers And In Immune
Privileged Tissues ............................................................... 78
Chapter 15: Immunologic Tolerance And Autoimmunity .................. 87
Chapter 16: Immunity To Microbes ........................................... 94
Chapter 17: Transplantation Immunology .................................. 101
Chapter 18: Tumor Immunology ............................................. 108
Chapter 19: Hypersensitivity Disorders ..................................... 114
Chapter 20: Allergy ............................................................ 120
Chapter 21: Primary And Acquired Immunodeficiencies ................. 125
Page | 2
, Cellular and Molecular Immunology, 10th Edition
Chapter 01: Properties And Overview Of Immune
Responses
Abbas, Lichtman, And Pillai: Cellular And Molecular Immunology, 10th
Edition
Multiple Choice
1. The Principal Function Of The Immune System Is:
A. Defense Against Cancer
B. Repair Of Injured Tissues
C. Defense Against Microbial Infections
D. Prevention Of Inflammatory Diseases
E. Protection Against Environmental Toxins
Answer: C
The Immune System Has Evolved In The Setting Of Selective Pressures
Imposed By Microbial Infections. Although Immune Responses To Cancer
May Occur, The Concept That “Immunosurveillance” Against Cancer Is A
Principal Function Of The Immune System Is Controversial. Repair Of
Injured Tissues May Be A Secondary Consequence Of The Immune
Responses And Inflammation. Although The Immune System Has
Regulatory Features That Are Needed To Prevent Excessive Inflammation,
Prevention Of Inflammatory Diseases Is Not A Primary Function. The
Immune System Can Protect Against Microbial Toxins, But It Generally
Does Not Offer Protection Against Toxins Of Nonbiologic Origin.
2. Which Of The Following Infectious Diseases Was Prevented By The
First Successful Vaccination?
A. Polio
B. Tuberculosis
C. Smallpox
D. Tetanus
E. Rubella
Page | 3
, Cellular and Molecular Immunology, 10th Edition
Answer: C
In 1798, Edward Jenner Reported The First Intentional Successful
Vaccination, Which Was Against Smallpox In A Boy, Using Material From
The Cowpox Pustules Of A Milkmaid. In 1980, Smallpox Was Reported To
Be Eradicated Worldwide By A Vaccination Program. Effective Vaccines
Against Tetanus Toxin, Rubella Virus, And Poliovirus Were Developed In
The 20th Century And Are Widely Used. There Is No Effective Vaccine
Against Mycobacterium Tuberculosis.
3. Which Of The Following Is A Unique Property Of The Adaptive
Immune System?
A. Highly Diverse Repertoire Of Specificities For Antigens
B. Self-Nonself Discrimination
C. Recognition Of Microbial Structures By Both Cell-Associated And
Soluble Receptors
D. Protection Against Viral Infections
E. Responses That Have The Same Kinetics And Magnitude On Repeated
Exposure To The Same Microbe
Answer: A
Highly Diverse Repertoires Of Specificities For Antigens Are Found Only In
T And B Lymphocytes, Which Are The Central Cellular Components Of The
Adaptive Immune System. Both The Innate And The Adaptive Immune
Systems Use Cell-Associated And Soluble Receptors To Recognize
Microbes, Display Some Degree Of Self-Nonself Discrimination, And
Protect Against Viruses. On Repeated Exposure To The Same Microbe, The
Adaptive Immune Response Becomes More Rapid And Of Greater
Magnitude; This Is The Manifestation Of Memory.
Page | 4
Complete Test Bank –
Cellular And Molecular Immunology,
10th Edition (Abbas, 2022),
Chapter 1-21 | All Chapters
Page | 1
, Cellular and Molecular Immunology, 10th Edition
Table Of Contents
Chapter 01: Properties And Overview Of Immune Responses .............. 3
Chapter 02: Cells And Tissues Of The Immune System ...................... 6
Chapter 03: Leukocyte Circulation And Migration Into Tissues .......... 10
Chapter 04: Innate Immunity ................................................. 15
Chapter 05: Antibodies And Antigens ........................................ 25
Chapter 06: Antigen Presentation To T Lymphocytes And The Functions
Of Major Histocompatibility Complex Molecules........................... 29
Chapter 07: Immune Receptors And Signal Transduction ................. 38
Chapter 08: Lymphocyte Development And Antigen Receptor Gene
Rearrangement .................................................................. 42
Chapter 09: Activation Of T Lymphocytes................................... 47
Chapter 10: Differentiation And Functions Of Cd4+ Effector T Cells ... 53
Chapter 11: Differentiation And Functions Of Cd8+ Effector T Cells ... 59
Chapter 12: B Cell Activation And Antibody Production .................. 64
Chapter 13: Effector Mechanisms Of Humoral Immunity ................. 72
Chapter 14: Specialized Immunity At Epithelial Barriers And In Immune
Privileged Tissues ............................................................... 78
Chapter 15: Immunologic Tolerance And Autoimmunity .................. 87
Chapter 16: Immunity To Microbes ........................................... 94
Chapter 17: Transplantation Immunology .................................. 101
Chapter 18: Tumor Immunology ............................................. 108
Chapter 19: Hypersensitivity Disorders ..................................... 114
Chapter 20: Allergy ............................................................ 120
Chapter 21: Primary And Acquired Immunodeficiencies ................. 125
Page | 2
, Cellular and Molecular Immunology, 10th Edition
Chapter 01: Properties And Overview Of Immune
Responses
Abbas, Lichtman, And Pillai: Cellular And Molecular Immunology, 10th
Edition
Multiple Choice
1. The Principal Function Of The Immune System Is:
A. Defense Against Cancer
B. Repair Of Injured Tissues
C. Defense Against Microbial Infections
D. Prevention Of Inflammatory Diseases
E. Protection Against Environmental Toxins
Answer: C
The Immune System Has Evolved In The Setting Of Selective Pressures
Imposed By Microbial Infections. Although Immune Responses To Cancer
May Occur, The Concept That “Immunosurveillance” Against Cancer Is A
Principal Function Of The Immune System Is Controversial. Repair Of
Injured Tissues May Be A Secondary Consequence Of The Immune
Responses And Inflammation. Although The Immune System Has
Regulatory Features That Are Needed To Prevent Excessive Inflammation,
Prevention Of Inflammatory Diseases Is Not A Primary Function. The
Immune System Can Protect Against Microbial Toxins, But It Generally
Does Not Offer Protection Against Toxins Of Nonbiologic Origin.
2. Which Of The Following Infectious Diseases Was Prevented By The
First Successful Vaccination?
A. Polio
B. Tuberculosis
C. Smallpox
D. Tetanus
E. Rubella
Page | 3
, Cellular and Molecular Immunology, 10th Edition
Answer: C
In 1798, Edward Jenner Reported The First Intentional Successful
Vaccination, Which Was Against Smallpox In A Boy, Using Material From
The Cowpox Pustules Of A Milkmaid. In 1980, Smallpox Was Reported To
Be Eradicated Worldwide By A Vaccination Program. Effective Vaccines
Against Tetanus Toxin, Rubella Virus, And Poliovirus Were Developed In
The 20th Century And Are Widely Used. There Is No Effective Vaccine
Against Mycobacterium Tuberculosis.
3. Which Of The Following Is A Unique Property Of The Adaptive
Immune System?
A. Highly Diverse Repertoire Of Specificities For Antigens
B. Self-Nonself Discrimination
C. Recognition Of Microbial Structures By Both Cell-Associated And
Soluble Receptors
D. Protection Against Viral Infections
E. Responses That Have The Same Kinetics And Magnitude On Repeated
Exposure To The Same Microbe
Answer: A
Highly Diverse Repertoires Of Specificities For Antigens Are Found Only In
T And B Lymphocytes, Which Are The Central Cellular Components Of The
Adaptive Immune System. Both The Innate And The Adaptive Immune
Systems Use Cell-Associated And Soluble Receptors To Recognize
Microbes, Display Some Degree Of Self-Nonself Discrimination, And
Protect Against Viruses. On Repeated Exposure To The Same Microbe, The
Adaptive Immune Response Becomes More Rapid And Of Greater
Magnitude; This Is The Manifestation Of Memory.
Page | 4
