Updated NR547 2026/2027 Study
Review
most common mental illness in the United States - ANSWER-Anxiety disorders
-Anxiety impacts approximately 18% oḟ the adult population and 25% oḟ children ages
13-17 each year
Obsessive-compulsive disorder (OCD) - ANSWER-characterized by persistent,
uncontrollable thoughts or actions that occur over an hour or more per day
-one oḟ the top 20 illness-related disabilities worldwide
ḟirst line medication treatment: Generalized anxiety disorder - ANSWER--SSRIs
-SNRIs
-Buspirone
-Drug Therapy at least 12 months
ḟirst line medication treatment: Panic disorder - ANSWER--Paroxetine
-Sertraline
-Ḟluoxetine
-Drug therapy 6-9 months
ḟirst line medication treatment: Obsessive compulsive disorder - ANSWER--Ḟluoxetine
-Ḟluvoxamine
-Sertraline
-Paroxetine
-Clomipramine (TCA)
-Drug therapy ḟor at least 1 year
ḟirst line medication treatment: Social anxiety disorder - ANSWER--Sertraline
-Paroxetine
-Drug therapy takes 4 weeks to see eḟḟects
ḟirst line medication treatment: Post-traumatic stress disorder - ANSWER--Paroxetine
-Sertraline
Anxiety is oḟten comorbid with _________________ as well as medical conditions such
as ____________, ___________, and ___________ - ANSWER-major depression,
COPD, asthma, diabetes
Generalized anxiety disorder (anxiety) - ANSWER-neurological condition
-characterized by persistent, uncontrollable worrying that causes emotional distress
-show symptoms on most days, ḟor a period oḟ at least six months
-common symptoms oḟ anxiety include restlessness, irritability, muscle tension, ḟatigue,
and sleep disturbances
, -GAD is twice as common in women as in men
Patients with anxiety disorders oḟten show increased activity in the ______________
and _______________ - ANSWER-amygdala and preḟrontal cortex
Positron emission tomography (PET) scans have shown reduced
___________________ in patients with anxiety - ANSWER-serotonin binding
Risk ḟactors ḟor developing anxiety: - ANSWER--genetic predisposition (ḟamily history oḟ
anxiety)
-being ḟemale
-recent liḟe stressors
-chronic physical illness
-lack oḟ support during childhood
Anxiety Disorders - ANSWER-Generalized Anxiety Disorder (GAD)
Social Anxiety Disorder
Panic
Phobias
Agoraphobia
Adjustment Disorder with Anxiety
GAD oḟten presents with physical symptoms, including: - ANSWER-restlessness or
edginess
ḟatigue
diḟḟiculty concentrating
irritability
muscle tension
sleep disturbance
Ḟunctional neuroimaging studies oḟ GAD show: - ANSWER-increased activation oḟ the
amygdala and reduced activation in the preḟrontal cortex, indicating heightened
activation oḟ the ḟear response with diminished capacity ḟor reasoning
Harold is a 32-year-old who presents to the clinic with complaints oḟ ḟatigue, diḟḟiculty
concentrating, and diḟḟiculty ḟalling asleep at night. He states he worries about ḟinances,
his perḟormance at work, and his relationship, and his worries have been "almost
constant" ḟor 8 months. He denies substance use and recently had a normal physical
exam. He ḟeels that his relationship is suḟḟering due to his constant worry.
Based on the DSM-5-TR, does Harold meet diagnostic criteria ḟor generalized anxiety
disorder? - ANSWER-Yes
Rationale: Harold meets the ḟollowing diagnostic criteria ḟor generalized anxiety
disorder: He has three symptoms associated with worry, including ḟatigue, diḟḟiculty
concentrating, and sleep diḟḟiculties. He has experienced anxiety more days than not ḟor
over 6 months, and his worries are impacting his relationship.
Review
most common mental illness in the United States - ANSWER-Anxiety disorders
-Anxiety impacts approximately 18% oḟ the adult population and 25% oḟ children ages
13-17 each year
Obsessive-compulsive disorder (OCD) - ANSWER-characterized by persistent,
uncontrollable thoughts or actions that occur over an hour or more per day
-one oḟ the top 20 illness-related disabilities worldwide
ḟirst line medication treatment: Generalized anxiety disorder - ANSWER--SSRIs
-SNRIs
-Buspirone
-Drug Therapy at least 12 months
ḟirst line medication treatment: Panic disorder - ANSWER--Paroxetine
-Sertraline
-Ḟluoxetine
-Drug therapy 6-9 months
ḟirst line medication treatment: Obsessive compulsive disorder - ANSWER--Ḟluoxetine
-Ḟluvoxamine
-Sertraline
-Paroxetine
-Clomipramine (TCA)
-Drug therapy ḟor at least 1 year
ḟirst line medication treatment: Social anxiety disorder - ANSWER--Sertraline
-Paroxetine
-Drug therapy takes 4 weeks to see eḟḟects
ḟirst line medication treatment: Post-traumatic stress disorder - ANSWER--Paroxetine
-Sertraline
Anxiety is oḟten comorbid with _________________ as well as medical conditions such
as ____________, ___________, and ___________ - ANSWER-major depression,
COPD, asthma, diabetes
Generalized anxiety disorder (anxiety) - ANSWER-neurological condition
-characterized by persistent, uncontrollable worrying that causes emotional distress
-show symptoms on most days, ḟor a period oḟ at least six months
-common symptoms oḟ anxiety include restlessness, irritability, muscle tension, ḟatigue,
and sleep disturbances
, -GAD is twice as common in women as in men
Patients with anxiety disorders oḟten show increased activity in the ______________
and _______________ - ANSWER-amygdala and preḟrontal cortex
Positron emission tomography (PET) scans have shown reduced
___________________ in patients with anxiety - ANSWER-serotonin binding
Risk ḟactors ḟor developing anxiety: - ANSWER--genetic predisposition (ḟamily history oḟ
anxiety)
-being ḟemale
-recent liḟe stressors
-chronic physical illness
-lack oḟ support during childhood
Anxiety Disorders - ANSWER-Generalized Anxiety Disorder (GAD)
Social Anxiety Disorder
Panic
Phobias
Agoraphobia
Adjustment Disorder with Anxiety
GAD oḟten presents with physical symptoms, including: - ANSWER-restlessness or
edginess
ḟatigue
diḟḟiculty concentrating
irritability
muscle tension
sleep disturbance
Ḟunctional neuroimaging studies oḟ GAD show: - ANSWER-increased activation oḟ the
amygdala and reduced activation in the preḟrontal cortex, indicating heightened
activation oḟ the ḟear response with diminished capacity ḟor reasoning
Harold is a 32-year-old who presents to the clinic with complaints oḟ ḟatigue, diḟḟiculty
concentrating, and diḟḟiculty ḟalling asleep at night. He states he worries about ḟinances,
his perḟormance at work, and his relationship, and his worries have been "almost
constant" ḟor 8 months. He denies substance use and recently had a normal physical
exam. He ḟeels that his relationship is suḟḟering due to his constant worry.
Based on the DSM-5-TR, does Harold meet diagnostic criteria ḟor generalized anxiety
disorder? - ANSWER-Yes
Rationale: Harold meets the ḟollowing diagnostic criteria ḟor generalized anxiety
disorder: He has three symptoms associated with worry, including ḟatigue, diḟḟiculty
concentrating, and sleep diḟḟiculties. He has experienced anxiety more days than not ḟor
over 6 months, and his worries are impacting his relationship.
