MCB 100 Antimicrobials Exam 3#1 Questions with
correct answers
Pual Ehrlich - ✔✔- Magic bullets (Chemicals aimed to kill pathogens w/o harming
the host)
- ex. Arsenic
Alexander Fleming - ✔✔Penicillin released from Penicillium and killed nearby
bacteria
Selman Waksman - ✔✔- Antibiotics (antimicrobial agents produced naturally by
organisms)
Workflow for developing Antimicrobials - ✔✔find antimicrobial agent --> isolate
active compound --> chemical synthesis of active compound
Principles of antimicrobials - ✔✔- Successful chemotherapy requires selective
toxicity (antimicrobial agent must be more toxic to a pathogen than the host)
- Antibacterial Drugs constitute the largest number and diversity
- Fewer drugs to treat eukaryotic infections (Toxic to host becuase cellular
machinery is similar)
- Antiviral drugs limited (often toxic to host because viruses largely require host
factors to replicate)
correct answers
Pual Ehrlich - ✔✔- Magic bullets (Chemicals aimed to kill pathogens w/o harming
the host)
- ex. Arsenic
Alexander Fleming - ✔✔Penicillin released from Penicillium and killed nearby
bacteria
Selman Waksman - ✔✔- Antibiotics (antimicrobial agents produced naturally by
organisms)
Workflow for developing Antimicrobials - ✔✔find antimicrobial agent --> isolate
active compound --> chemical synthesis of active compound
Principles of antimicrobials - ✔✔- Successful chemotherapy requires selective
toxicity (antimicrobial agent must be more toxic to a pathogen than the host)
- Antibacterial Drugs constitute the largest number and diversity
- Fewer drugs to treat eukaryotic infections (Toxic to host becuase cellular
machinery is similar)
- Antiviral drugs limited (often toxic to host because viruses largely require host
factors to replicate)
