WILKES NSG 533 EXAM 1 ADVANCED PHARMACOLOGY STUDY GUIDE ()

WILKES NSG 533 EXAM 1 ADVANCED PHARMACOLOGY EDITION

2026 - 2027 WITH ALL CORRECT VERIFIED QUESTIONS AND

ANSWERS GUARANTEED PASS



Wilkes NSG 533 Advanced Pharmacology – Exam 1 Practice (150 Questions with Answers)


Pharmacokinetics & Pharmacodynamics (1–25)


1. Which process is most affected in a patient with liver failure?

A. Absorption

B. Distribution

C. Metabolism

D. Excretion

Answer: C



2. First-pass metabolism occurs primarily in the:

A. Kidney

B. Liver

C. Lung

, D. Intestine

Answer: B




3. A drug with high protein binding will:

A. Have a shorter half-life

B. Remain in circulation longer

C. Be rapidly excreted

D. Not distribute to tissues

Answer: B



4. Bioavailability refers to:

A. Drug clearance

B. Rate of absorption

C. Fraction reaching systemic circulation

D. Drug half-life

Answer: C




5. Steady state is typically achieved after:

A. 1 half-life

B. 2 half-lives

C. 4–5 half-lives

, D. 10 half-lives

Answer: C



6. Volume of distribution reflects:

A. Kidney function

B. Drug distribution in tissues

C. Liver enzyme activity

D. Drug potency

Answer: B




7. Which drug type is most affected by renal impairment?

A. Lipid soluble drugs

B. Water soluble drugs

C. Highly protein-bound drugs

D. Inhaled drugs

Answer: B



8. Agonists produce effects by:

A. Blocking receptors

B. Activating receptors

C. Destroying enzymes