WGU BIOCHEMISTRY OA STUDY GUIDE 2026 COMPREHENSIVE QUESTIONS AND STEP BY STEP SOLUTIONS

WGU BIOCHEMISTRY OA STUDY GUIDE
2026 COMPREHENSIVE QUESTIONS AND
STEP BY STEP SOLUTIONS

◉ Base excision repair
Answer: -only 1 nucleotide damaged
- remove and replace


◉ Nucleotide excision repair
Answer: -more than 1 nucleotide damaged
-cut a sequence & replace that section


◉ Mismatch repair
Answer: -happens in mistakes with DNA replication
-DNA polymerase proofreads to see if make a right choice, but makes
a mistake.
-remove big section of damage and replace all of it


◉ Homologous recombination
Answer: -use 2nd copy of the DNA to copy back the correct info
- double strand (cut DNA in 2), break

, ◉ Non-homologous end-joining
Answer: -happens before DNA replication
-trim the ends-stuck back together


◉ PCR
Answer: -DNA replication in a test tube
-Denature, Anneal, Elongation, Repeat


◉ Denature
Answer: -step 1 of PCR
-increase heat to separate the DNA


◉ Anneal
Answer: -step 2 of PCR
-use DNA primers that match the gene to find only the gene we want
(ex: to find BRCA gene)


◉ Elongation
Answer: -step 3 of PCR
-use DNA polymerase to make copies of our genes