Nurse 125 Exam 4 Questions with
Verified Solutions
What is the pathophysiology of rheumatoid arthritis? - ANS-Long-term exposure to
unidentified antigen
Normal antibodies become autoantibodies called rheumatoid factors
Cartilage damage from three processes Neutrophils, T cells, other synovial fluid cells
activated, degrade surface layer of articular cartilage
Cytokines cause chondrocytes to attack cartilage
Synovium digests nearby cartilage Formation of pannus tissue
List the general joint manifestation of rheumatoid arthritis - ANS-Typically polyarticular
symmetrical Stiffness In morning lasting more than 1 hour
May be more severe after strenuous activity
Feel spongelike
may be weakness
Clinical Manifestations of Rheumatoid Arthritis in the hands and fingers - ANS-Swan-
neck deformity
Boutonnière deformity
Clinical Manifestations of Rheumatoid Arthritis in the knees - ANS-•Visible swelling
•Joint instability
•Quadriceps atrophy
•Contractures
•Knock-knee
Clinical Manifestations of Rheumatoid Arthritis in the ankles & knees - ANS-•Ambulation
limited by pain, deformities
•Subluxation
•Hallux valgus, lateral deviation of toes
•Cock-up toes
,Clinical Manifestations of Rheumatoid Arthritis in the spine - ANS-•Usually limited to
cervical vertebrae
•Neck pain
•Neurologic complications
Sensory clinical Manifestations of Rheumatoid Arthritis - ANS-Scleritis
Episcleritis
Exocrine gland clinical Manifestations of Rheumatoid Arthritis - ANS-Sjogren syndrome
- dry eyes
- dry mouth
Cardiovascular clinical Manifestations of Rheumatoid Arthritis - ANS-vasculitis
pericarditis
Hematologic clinical Manifestations of Rheumatoid Arthritis - ANS-Felty syndrome
- splenomegaly
- neutropenia
- anemia
Integumentary clinical Manifestations of Rheumatoid Arthritis - ANS-rheumatiod nodules
Respiratory clinical Manifestations of Rheumatoid Arthritis - ANS-pleural disease
interstitial fibrosis
pneumonitis
Musculoskeletal (general) clinical Manifestations of Rheumatoid Arthritis - ANS-
symmetric polyarticular joint swelling
joint redness
warmth
pain
tenderness
morning stiffness
Musculoskeletal (spine) clinical Manifestations of Rheumatoid Arthritis - ANS-cervical
pain
neurologic manifestations
, Musculoskeletal (wrists) clinical Manifestations of Rheumatoid Arthritis - ANS-limited
ROM
deformity
carpal tunnel syndrome
Musculoskeletal (hands) clinical Manifestations of Rheumatoid Arthritis - ANS-ulnar
deviation
swan-neck deformity
boutonniere deformity
Musculoskeletal (knees) clinical Manifestations of Rheumatoid Arthritis - ANS-joint
effusion
instability
Musculoskeletal (ankles) clinical Manifestations of Rheumatoid Arthritis - ANS-Limited
ROM
pain of ambulation
Musculoskeletal (feet) clinical Manifestations Musculoskeletal (general) clinical
Manifestations of Rheumatoid Arthritis - ANS-subluxation
Risk Factors of Rheumatoid Arthritis - ANS-- Family history of RA
- HLA - DR4 genetic marker increases the
risk five times
- Heavy smokers
- Obesity
- Physical, emotional trauma
- Exposure to air pollution, insecticides
-Occupational exposures
Diagnostic tests - ANS--Complete blood count (CBC)
-Rheumatoid factors
-Antibodies to cyclic citrullinated peptide (CCP)
-Erythrocyte sedimentation rate
-C-reactive protein
-X-rays of affected joints
•Rule out other causes of joint pain
Verified Solutions
What is the pathophysiology of rheumatoid arthritis? - ANS-Long-term exposure to
unidentified antigen
Normal antibodies become autoantibodies called rheumatoid factors
Cartilage damage from three processes Neutrophils, T cells, other synovial fluid cells
activated, degrade surface layer of articular cartilage
Cytokines cause chondrocytes to attack cartilage
Synovium digests nearby cartilage Formation of pannus tissue
List the general joint manifestation of rheumatoid arthritis - ANS-Typically polyarticular
symmetrical Stiffness In morning lasting more than 1 hour
May be more severe after strenuous activity
Feel spongelike
may be weakness
Clinical Manifestations of Rheumatoid Arthritis in the hands and fingers - ANS-Swan-
neck deformity
Boutonnière deformity
Clinical Manifestations of Rheumatoid Arthritis in the knees - ANS-•Visible swelling
•Joint instability
•Quadriceps atrophy
•Contractures
•Knock-knee
Clinical Manifestations of Rheumatoid Arthritis in the ankles & knees - ANS-•Ambulation
limited by pain, deformities
•Subluxation
•Hallux valgus, lateral deviation of toes
•Cock-up toes
,Clinical Manifestations of Rheumatoid Arthritis in the spine - ANS-•Usually limited to
cervical vertebrae
•Neck pain
•Neurologic complications
Sensory clinical Manifestations of Rheumatoid Arthritis - ANS-Scleritis
Episcleritis
Exocrine gland clinical Manifestations of Rheumatoid Arthritis - ANS-Sjogren syndrome
- dry eyes
- dry mouth
Cardiovascular clinical Manifestations of Rheumatoid Arthritis - ANS-vasculitis
pericarditis
Hematologic clinical Manifestations of Rheumatoid Arthritis - ANS-Felty syndrome
- splenomegaly
- neutropenia
- anemia
Integumentary clinical Manifestations of Rheumatoid Arthritis - ANS-rheumatiod nodules
Respiratory clinical Manifestations of Rheumatoid Arthritis - ANS-pleural disease
interstitial fibrosis
pneumonitis
Musculoskeletal (general) clinical Manifestations of Rheumatoid Arthritis - ANS-
symmetric polyarticular joint swelling
joint redness
warmth
pain
tenderness
morning stiffness
Musculoskeletal (spine) clinical Manifestations of Rheumatoid Arthritis - ANS-cervical
pain
neurologic manifestations
, Musculoskeletal (wrists) clinical Manifestations of Rheumatoid Arthritis - ANS-limited
ROM
deformity
carpal tunnel syndrome
Musculoskeletal (hands) clinical Manifestations of Rheumatoid Arthritis - ANS-ulnar
deviation
swan-neck deformity
boutonniere deformity
Musculoskeletal (knees) clinical Manifestations of Rheumatoid Arthritis - ANS-joint
effusion
instability
Musculoskeletal (ankles) clinical Manifestations of Rheumatoid Arthritis - ANS-Limited
ROM
pain of ambulation
Musculoskeletal (feet) clinical Manifestations Musculoskeletal (general) clinical
Manifestations of Rheumatoid Arthritis - ANS-subluxation
Risk Factors of Rheumatoid Arthritis - ANS-- Family history of RA
- HLA - DR4 genetic marker increases the
risk five times
- Heavy smokers
- Obesity
- Physical, emotional trauma
- Exposure to air pollution, insecticides
-Occupational exposures
Diagnostic tests - ANS--Complete blood count (CBC)
-Rheumatoid factors
-Antibodies to cyclic citrullinated peptide (CCP)
-Erythrocyte sedimentation rate
-C-reactive protein
-X-rays of affected joints
•Rule out other causes of joint pain