,APEA Pre-Predictor Adult-Gerontology
& Family Nurse Practitioner
Comprehensive Review Examination
100 full questions with correct
answers graded a+ for 2026
Question 1
A 9-year-old presents with fever, sore throat, headache, cervical lymphadenopathy, and a fine
sandpaper-like rash over the trunk. Which diagnosis is most likely?
A. Rubella
B. Scarlet fever
C. Roseola
D. Fifth disease
Correct Answer: B. Scarlet fever
Rationale:
Scarlet fever is caused by Group A beta-hemolytic Streptococcus and presents with fever,
pharyngitis, cervical lymphadenopathy, and a characteristic sandpaper rash that later
desquamates.
Question 2
A patient begins levothyroxine therapy for newly diagnosed hypothyroidism. When should TSH
be rechecked?
A. 1 week
,B. 2 weeks
C. 6 weeks
D. 6 months
Correct Answer: C. 6 weeks
Rationale:
Because levothyroxine has a long half-life (approximately 7 days), meaningful TSH changes are
seen after approximately 4–6 weeks. Rechecking at six weeks is recommended.
Question 3
A male with a history of cryptorchidism should receive counseling regarding:
A. Colon cancer screening
B. Monthly testicular self-examinations
C. Annual PSA testing beginning at age 30
D. Annual CT abdomen
Correct Answer: B. Monthly testicular self-examinations
Rationale:
Cryptorchidism significantly increases the lifetime risk for testicular cancer. Patients should
perform regular testicular self-examinations.
Question 4
The preferred treatment for chronic bacterial prostatitis is:
A. Nitrofurantoin
B. Amoxicillin
C. Fluoroquinolone therapy
D. Doxycycline
Correct Answer: C. Fluoroquinolone therapy
, Rationale:
Fluoroquinolones achieve excellent prostate penetration and are first-line therapy for chronic
bacterial prostatitis for 3 weeks to 4 months.
Question 5
A woman reports frequent recurrent vaginal yeast infections. Which underlying condition
should be ruled out?
A. Hypertension
B. Diabetes mellitus
C. Asthma
D. Osteoarthritis
Correct Answer: B. Diabetes mellitus
Rationale:
Recurrent candidal infections are frequently associated with poorly controlled diabetes mellitus.
Question 6
An S3 heart sound is best described as:
A. Closure of the semilunar valves
B. Closure of the AV valves
C. Rapid ventricular filling after S2
D. Aortic stenosis
Correct Answer: C. Rapid ventricular filling after S2
Rationale:
An S3 occurs immediately after S2 during rapid ventricular filling and is a low-pitched sound.
Question 7
A PSA level of 12 ng/mL is most concerning for:
& Family Nurse Practitioner
Comprehensive Review Examination
100 full questions with correct
answers graded a+ for 2026
Question 1
A 9-year-old presents with fever, sore throat, headache, cervical lymphadenopathy, and a fine
sandpaper-like rash over the trunk. Which diagnosis is most likely?
A. Rubella
B. Scarlet fever
C. Roseola
D. Fifth disease
Correct Answer: B. Scarlet fever
Rationale:
Scarlet fever is caused by Group A beta-hemolytic Streptococcus and presents with fever,
pharyngitis, cervical lymphadenopathy, and a characteristic sandpaper rash that later
desquamates.
Question 2
A patient begins levothyroxine therapy for newly diagnosed hypothyroidism. When should TSH
be rechecked?
A. 1 week
,B. 2 weeks
C. 6 weeks
D. 6 months
Correct Answer: C. 6 weeks
Rationale:
Because levothyroxine has a long half-life (approximately 7 days), meaningful TSH changes are
seen after approximately 4–6 weeks. Rechecking at six weeks is recommended.
Question 3
A male with a history of cryptorchidism should receive counseling regarding:
A. Colon cancer screening
B. Monthly testicular self-examinations
C. Annual PSA testing beginning at age 30
D. Annual CT abdomen
Correct Answer: B. Monthly testicular self-examinations
Rationale:
Cryptorchidism significantly increases the lifetime risk for testicular cancer. Patients should
perform regular testicular self-examinations.
Question 4
The preferred treatment for chronic bacterial prostatitis is:
A. Nitrofurantoin
B. Amoxicillin
C. Fluoroquinolone therapy
D. Doxycycline
Correct Answer: C. Fluoroquinolone therapy
, Rationale:
Fluoroquinolones achieve excellent prostate penetration and are first-line therapy for chronic
bacterial prostatitis for 3 weeks to 4 months.
Question 5
A woman reports frequent recurrent vaginal yeast infections. Which underlying condition
should be ruled out?
A. Hypertension
B. Diabetes mellitus
C. Asthma
D. Osteoarthritis
Correct Answer: B. Diabetes mellitus
Rationale:
Recurrent candidal infections are frequently associated with poorly controlled diabetes mellitus.
Question 6
An S3 heart sound is best described as:
A. Closure of the semilunar valves
B. Closure of the AV valves
C. Rapid ventricular filling after S2
D. Aortic stenosis
Correct Answer: C. Rapid ventricular filling after S2
Rationale:
An S3 occurs immediately after S2 during rapid ventricular filling and is a low-pitched sound.
Question 7
A PSA level of 12 ng/mL is most concerning for:
