, APEA Pre-Predictor NP Exam Review
2026-2027 100 questions with correct
answers graded a+ assured excel!!
Question 101
A 58-year-old man with long-standing hypertension presents with exertional chest pressure that
resolves after resting for five minutes. Which diagnosis is most likely?
A. Unstable angina
B. Stable angina
C. Acute myocardial infarction
D. Pericarditis
Correct Answer: B. Stable angina
Rationale:
Stable angina is characterized by predictable chest discomfort brought on by exertion or
emotional stress and relieved with rest or nitroglycerin.
Question 102
Which antihypertensive medication should generally be avoided during pregnancy?
A. Labetalol
B. Nifedipine
C. Methyldopa
D. Lisinopril
Correct Answer: D. Lisinopril
Rationale:
ACE inhibitors are contraindicated during pregnancy because they can cause fetal renal failure,
oligohydramnios, and fetal death.
,Question 103
A patient with diabetic neuropathy complains of burning pain in both feet. Which medication is
considered first-line treatment?
A. Acetaminophen
B. Gabapentin
C. Penicillin
D. Prednisone
Correct Answer: B. Gabapentin
Rationale:
Gabapentin is commonly used as first-line therapy for painful diabetic peripheral neuropathy.
Question 104
Which laboratory test best reflects long-term glycemic control?
A. Random glucose
B. Fasting glucose
C. Hemoglobin A1c
D. Urine glucose
Correct Answer: C. Hemoglobin A1c
Rationale:
Hemoglobin A1c reflects the average blood glucose over approximately three months and is the
standard measure of long-term diabetes control.
Question 105
A patient with chronic kidney disease should avoid which analgesic because it may worsen renal
function?
A. Acetaminophen
, B. Ibuprofen
C. Tramadol
D. Lidocaine patch
Correct Answer: B. Ibuprofen
Rationale:
NSAIDs reduce renal blood flow and may accelerate kidney injury in patients with chronic
kidney disease.
Question 106
A patient develops sudden unilateral facial drooping but can still wrinkle the forehead. Which
diagnosis is most likely?
A. Bell palsy
B. Ischemic stroke
C. Trigeminal neuralgia
D. Migraine
Correct Answer: B. Ischemic stroke
Rationale:
Forehead sparing indicates an upper motor neuron lesion, suggesting stroke rather than Bell
palsy.
Question 107
Which electrolyte abnormality is most commonly associated with loop diuretics?
A. Hyperkalemia
B. Hypokalemia
C. Hypermagnesemia
D. Hypercalcemia
Correct Answer: B. Hypokalemia
2026-2027 100 questions with correct
answers graded a+ assured excel!!
Question 101
A 58-year-old man with long-standing hypertension presents with exertional chest pressure that
resolves after resting for five minutes. Which diagnosis is most likely?
A. Unstable angina
B. Stable angina
C. Acute myocardial infarction
D. Pericarditis
Correct Answer: B. Stable angina
Rationale:
Stable angina is characterized by predictable chest discomfort brought on by exertion or
emotional stress and relieved with rest or nitroglycerin.
Question 102
Which antihypertensive medication should generally be avoided during pregnancy?
A. Labetalol
B. Nifedipine
C. Methyldopa
D. Lisinopril
Correct Answer: D. Lisinopril
Rationale:
ACE inhibitors are contraindicated during pregnancy because they can cause fetal renal failure,
oligohydramnios, and fetal death.
,Question 103
A patient with diabetic neuropathy complains of burning pain in both feet. Which medication is
considered first-line treatment?
A. Acetaminophen
B. Gabapentin
C. Penicillin
D. Prednisone
Correct Answer: B. Gabapentin
Rationale:
Gabapentin is commonly used as first-line therapy for painful diabetic peripheral neuropathy.
Question 104
Which laboratory test best reflects long-term glycemic control?
A. Random glucose
B. Fasting glucose
C. Hemoglobin A1c
D. Urine glucose
Correct Answer: C. Hemoglobin A1c
Rationale:
Hemoglobin A1c reflects the average blood glucose over approximately three months and is the
standard measure of long-term diabetes control.
Question 105
A patient with chronic kidney disease should avoid which analgesic because it may worsen renal
function?
A. Acetaminophen
, B. Ibuprofen
C. Tramadol
D. Lidocaine patch
Correct Answer: B. Ibuprofen
Rationale:
NSAIDs reduce renal blood flow and may accelerate kidney injury in patients with chronic
kidney disease.
Question 106
A patient develops sudden unilateral facial drooping but can still wrinkle the forehead. Which
diagnosis is most likely?
A. Bell palsy
B. Ischemic stroke
C. Trigeminal neuralgia
D. Migraine
Correct Answer: B. Ischemic stroke
Rationale:
Forehead sparing indicates an upper motor neuron lesion, suggesting stroke rather than Bell
palsy.
Question 107
Which electrolyte abnormality is most commonly associated with loop diuretics?
A. Hyperkalemia
B. Hypokalemia
C. Hypermagnesemia
D. Hypercalcemia
Correct Answer: B. Hypokalemia
