AANP Practice Questions with correct
answers graded a+ for 2026-2027
assured excel!!
Question 201
A patient presents with episodic flushing, diarrhea, and wheezing. What is the most likely
diagnosis?
A. Addison disease
B. Carcinoid syndrome
C. IBS
D. Crohn disease
Correct Answer: B. Carcinoid syndrome
Rationale:
Carcinoid tumors release serotonin causing flushing, diarrhea, and bronchospasm.
Question 202
Which test is most specific for diagnosing acute pancreatitis?
A. ALT
B. Serum amylase
C. Serum lipase
D. Alkaline phosphatase
Correct Answer: C. Serum lipase
Rationale:
Lipase is more specific and remains elevated longer than amylase.
Question 203
,Which condition is associated with “pan-systolic murmur at left lower sternal border”?
A. Mitral regurgitation
B. Tricuspid regurgitation
C. Aortic stenosis
D. Pulmonic stenosis
Correct Answer: B. Tricuspid regurgitation
Rationale:
Tricuspid regurgitation is heard best at the left lower sternal border.
Question 204
Which condition is associated with “Fried egg appearance” on imaging?
A. Hodgkin lymphoma
B. Tuberculosis
C. Sarcoidosis
D. Pneumonia
Correct Answer: A. Hodgkin lymphoma
Rationale:
Reed-Sternberg cells give classic appearance in Hodgkin lymphoma.
Question 205
Which condition is associated with “positive Nikolsky sign”?
A. Psoriasis
B. Pemphigus vulgaris
C. Eczema
D. Tinea
Correct Answer: B. Pemphigus vulgaris
, Rationale:
Skin sloughing with pressure is seen in pemphigus vulgaris.
Question 206
Which electrolyte imbalance is most associated with vomiting and metabolic alkalosis?
A. Hyperkalemia
B. Hypokalemia
C. Hypercalcemia
D. Hypermagnesemia
Correct Answer: B. Hypokalemia
Rationale:
Vomiting leads to loss of gastric acid and potassium.
Question 207
Which condition is associated with “anchor-shaped cells” on smear?
A. Iron deficiency anemia
B. Sickle cell disease
C. Thalassemia
D. Aplastic anemia
Correct Answer: B. Sickle cell disease
Rationale:
Sickled erythrocytes appear crescent or anchor-shaped.
Question 208
Which condition is associated with “hyperresonance on percussion and absent breath sounds”?
A. Pneumonia
B. Pneumothorax
answers graded a+ for 2026-2027
assured excel!!
Question 201
A patient presents with episodic flushing, diarrhea, and wheezing. What is the most likely
diagnosis?
A. Addison disease
B. Carcinoid syndrome
C. IBS
D. Crohn disease
Correct Answer: B. Carcinoid syndrome
Rationale:
Carcinoid tumors release serotonin causing flushing, diarrhea, and bronchospasm.
Question 202
Which test is most specific for diagnosing acute pancreatitis?
A. ALT
B. Serum amylase
C. Serum lipase
D. Alkaline phosphatase
Correct Answer: C. Serum lipase
Rationale:
Lipase is more specific and remains elevated longer than amylase.
Question 203
,Which condition is associated with “pan-systolic murmur at left lower sternal border”?
A. Mitral regurgitation
B. Tricuspid regurgitation
C. Aortic stenosis
D. Pulmonic stenosis
Correct Answer: B. Tricuspid regurgitation
Rationale:
Tricuspid regurgitation is heard best at the left lower sternal border.
Question 204
Which condition is associated with “Fried egg appearance” on imaging?
A. Hodgkin lymphoma
B. Tuberculosis
C. Sarcoidosis
D. Pneumonia
Correct Answer: A. Hodgkin lymphoma
Rationale:
Reed-Sternberg cells give classic appearance in Hodgkin lymphoma.
Question 205
Which condition is associated with “positive Nikolsky sign”?
A. Psoriasis
B. Pemphigus vulgaris
C. Eczema
D. Tinea
Correct Answer: B. Pemphigus vulgaris
, Rationale:
Skin sloughing with pressure is seen in pemphigus vulgaris.
Question 206
Which electrolyte imbalance is most associated with vomiting and metabolic alkalosis?
A. Hyperkalemia
B. Hypokalemia
C. Hypercalcemia
D. Hypermagnesemia
Correct Answer: B. Hypokalemia
Rationale:
Vomiting leads to loss of gastric acid and potassium.
Question 207
Which condition is associated with “anchor-shaped cells” on smear?
A. Iron deficiency anemia
B. Sickle cell disease
C. Thalassemia
D. Aplastic anemia
Correct Answer: B. Sickle cell disease
Rationale:
Sickled erythrocytes appear crescent or anchor-shaped.
Question 208
Which condition is associated with “hyperresonance on percussion and absent breath sounds”?
A. Pneumonia
B. Pneumothorax
