ANSWERS|GRADED A+|GUARANTEED 100% PASS
Hypersensitivity: Type 1 -CORRECT ANSWER--Mediated IgE
-inflammation due to mast cell degranultion
-anaphylactic, asthma, hay fever
treatment: epinephrine
Hypersensitivity: Type 2 -CORRECT ANSWER--Cytotoxic reaction: tissue specific
-binds to the antigen ON THE CELL SURFACE
-macrophages are primary effectors cells involved
cause tissue damage or alter function
Hypersensitivity 2 -CORRECT ANSWER--Graves Disease (hyperthyroidism) -alters function not
destroy
-blood transfusions reaction- transfused erythrocytes are destroyed by agglutination or lysis
-drug allergies
-hemolytic anemia
Hypersensitivity: type 3 -CORRECT ANSWER--Not organ specific
-antibody binds to soluble antigen OUTSIDE THE CELL SURFACE that was released into the
blood or bodily fluids, and the complex is then deposited in the tissues
,Hypersensitivity: Type 3 -CORRECT ANSWER--rheumatoid arthritis
-Systemic Lupus Erythematosus (SLE)
-Raynaud's
Hives (urticaria) -CORRECT ANSWER-Hypersensitivity Type 1
First responders to innate the immune system -CORRECT ANSWER-Neutrophils
Allergic contact dermatitis -CORRECT ANSWER-Hypersensitivity Type IV
Type 2 cytotoxic hypersensitivity mediated by: -CORRECT ANSWER--IgG IgM
-macrophages are primary effort cells
-
Serum Sickness -CORRECT ANSWER-type 3 hypersensitivity
Hypersensitivity IV, -CORRECT ANSWER--is more of a delayed immune response.
-mediated T-cells attack tissue directly (no antibodies)
Autoimmune -CORRECT ANSWER--diseases in which the body makes antibodies directed
against its own tissues
-
Primary immunodeficiency -CORRECT ANSWER--Genetic; inherited
-result of single gene defects
-B and T cell deficiencies
secondary immunodeficiency -CORRECT ANSWER--acquired
, Common cause of secondary immunodeficiency -CORRECT ANSWER-Malnutrition
Most patients diagnosed with SLE will have a positive ? -CORRECT ANSWER-antinuclear
antibody (ANA)
SLE (lupus) -CORRECT ANSWER--Facial rash
-vasculitis
- tissue inflammation
Renal disease associated with autoimmunity? -CORRECT ANSWER-Glomerulonephritis
Sjogren's syndrome -CORRECT ANSWER-Inflammation in salivary and lacrimal glands
SLE -CORRECT ANSWER-Autoantibodies and auto-active t-cells against DNA and
nucleoprotein
Sjögren's syndrome immune changes: -CORRECT ANSWER-Autoantibodies and auto-reactive
t-cells against apoptotic cells
rheumatoid arthritis manifestations: -CORRECT ANSWER-Joint inflammation, stiffness, pain,
loss of range of motion
Rheumatoid Arthritis immune changes: -CORRECT ANSWER-T-cells and B cells against joint
associated antigens
MS manifestations -CORRECT ANSWER-Formation of sclerotic plaque in the brain, leads to
Muscle weakness and ataxia
MS immune changes -CORRECT ANSWER-T-cells against brain antigens