Questions: 150 Family Nurse Practitioner Practice
Questions with Answers and Rationales (2026
Edition) SOUTH UNIVERSITY
Introduction
Preparing for the NSG 6998 Family Nurse Practitioner (FNP) Predictor Exam requires a
comprehensive understanding of evidence-based clinical practice, patient assessment,
pharmacology, health promotion, disease prevention, and primary care management across the
lifespan. Success on the predictor examination depends on applying critical thinking skills to
realistic patient scenarios while selecting the most appropriate diagnostic, therapeutic, and
preventive interventions.
This review guide contains 150 original, certification-style multiple-choice practice questions
designed to strengthen your clinical reasoning and improve exam readiness. Every question
includes four answer choices, the correct answer, and a detailed rationale explaining why the
correct response is appropriate. The questions are modeled after the format commonly
encountered on FNP predictor examinations and national certification exams, making this
resource valuable for both graduate nursing students and practicing nurse practitioners preparing
for certification or recertification.
Whether you are preparing for the NSG 6998 Predictor, AANP, or ANCC Family Nurse
Practitioner Certification Examination, these practice questions provide an effective way to
assess your knowledge, identify learning gaps, and build confidence before exam day.
Coverage
This comprehensive review includes questions covering:
Primary Care Across the Lifespan
Adult and Geriatric Health
Pediatric Primary Care
Women's Health and Prenatal Care
Men's Health
Cardiovascular Disorders
, Respiratory Disorders
Endocrine Disorders
Diabetes Mellitus Management
Gastrointestinal Disorders
Renal and Genitourinary Disorders
Musculoskeletal Disorders
Neurologic Disorders
Dermatologic Disorders
Psychiatric and Mental Health Conditions
Infectious Diseases
Hematologic Disorders
Rheumatologic and Autoimmune Diseases
Ophthalmologic and Otologic Disorders
Preventive Health Screening
Health Promotion and Disease Prevention
Immunization Guidelines
Diagnostic Testing and Interpretation
Pharmacology and Medication Management
Evidence-Based Clinical Decision-Making
Emergency Recognition and Initial Management
Patient Education and Counseling
Health Maintenance Across the Lifespan
1. A 56-year-old woman with newly diagnosed essential hypertension has no
significant comorbidities and normal kidney function. Which medication is
considered an appropriate first-line pharmacologic treatment for controlling her
blood pressure?
A. Clonidine
B. Hydralazine
C. Lisinopril
D. Propranolol
Answer: C. Lisinopril
ACE inhibitors such as lisinopril are recommended first-line agents for many adults with
hypertension because they reduce cardiovascular risk and protect renal function. Clonidine
and hydralazine are generally reserved for resistant hypertension or specific clinical
situations.
,2. A 67-year-old man with a forty-pack-year smoking history presents with chronic
productive cough lasting longer than three months during consecutive years. Which
diagnosis most accurately explains his persistent respiratory symptoms?
A. Asthma
B. Chronic bronchitis
C. Pulmonary embolism
D. Lung abscess
Answer: B. Chronic bronchitis
Chronic bronchitis is defined by productive cough lasting at least three months in each of
two consecutive years. Cigarette smoking is the most common underlying cause.
3. A 24-year-old sexually active woman reports painful urination, urinary urgency,
and urinary frequency without fever or flank pain. Which diagnosis is the most likely
explanation for her symptoms?
A. Acute cystitis
B. Acute pyelonephritis
C. Nephrolithiasis
D. Interstitial nephritis
Answer: A. Acute cystitis
Acute cystitis commonly presents with dysuria, urinary urgency, and frequency without
systemic symptoms. Fever and flank pain would suggest pyelonephritis.
4. A 72-year-old man with long-standing type 2 diabetes mellitus should receive
regular examinations to detect which microvascular complication before irreversible
vision loss develops?
A. Cataracts
B. Diabetic retinopathy
C. Macular degeneration
D. Retinal detachment
Answer: B. Diabetic retinopathy
, Diabetic retinopathy is a common microvascular complication of diabetes. Annual dilated
eye examinations help identify retinal damage early and reduce the risk of blindness.
5. A 45-year-old woman complains of fatigue, cold intolerance, constipation, dry skin,
and gradual weight gain despite no significant dietary changes. Which endocrine
disorder most likely explains her clinical presentation?
A. Hyperthyroidism
B. Hypothyroidism
C. Cushing syndrome
D. Addison disease
Answer: B. Hypothyroidism
Hypothyroidism slows metabolic activity, producing fatigue, constipation, cold intolerance,
dry skin, bradycardia, and weight gain.
6. A healthy two-year-old child presents for a routine well-child examination. Which
developmental milestone should the family nurse practitioner expect the child to
demonstrate during the visit?
A. Walking independently
B. Speaking two-word phrases
C. Riding a bicycle independently
D. Writing complete sentences
Answer: B. Speaking two-word phrases
By two years of age, children commonly combine two-word phrases, follow simple
commands, run, and climb stairs with assistance.
7. A 63-year-old patient with chronic atrial fibrillation is prescribed anticoagulation
primarily to reduce the risk of developing which potentially life-threatening
complication?
A. Pulmonary fibrosis
B. Ischemic stroke