Clearance - Answers Rate at which a molecule disappears from the body
Mass Balance - Answers Existing body load + Intake or metabolic production - Excretion or metabolic
removal
Osmotic Equlibrium - Answers -Based on water (tonicity)
-Moves freely
Electrical Equilibrium - Answers Inside slightly more negative
Diffusion - Answers -Uses energy of molecular motion
-Does not use ATP
Na+ - Answers -Plasma
-Interstitial Fluid
Cl- - Answers -Plasma
-Interstitial Fluid
K+ - Answers Intracellular fluid
HCO3- - Answers -Plasma
-Interstitial Fluid
Large anions and proteins - Answers Intracellular fluid
Diffusion Seven Properties - Answers 1. Passive process
2. High concentration to low concentration
3. Net movement until concentration is equal
4. Rapid over short distances
5. Directly related to temperature
6. Inversely related to molecular size
7. In open system or across a partition
Channel Regulated - Answers size and charge continuous, fast, general
Carrier Regulated - Answers substrate not continuous, slow, specific
Na+-K+-ATPase - Answers 1. 3 Na+ from ICF bind
(ATP --> ADP)
2. ATPase is phosphorylated with P1 from ATP
(Protein changes conformation)
3. 3 Na+ released into ECF
4. 2 K+ from ECF bind
(Protein changes conformation)
5. 2 K+ released into ICF
NA/K ATPase - Answers uses 30% of all ATP produced by the cell
Phagocytosis - Answers -Cell engulfs bacterium or other particle into phagosome
-Pushes cell membrane
Endocytosis - Answers -Membrane surface indents and forms vesicles
-Active process that can be nonselective (pinocytosis) or highly selective
-Receptor-mediated uses clathrin-coated pits
-Smaller than phagosomes
Receptor-Mediated Endocytosis and Exocytosis - Answers 1. Ligand binds to membrane receptor.
2. Receptor-ligand migrated to clathrin-coated pit.
3. Endocytosis
4. Vesicle loses clathrin coat
5. Receptors and ligands separate.
6. Ligands go to lysosomes or Golgi for processing
7. Transport vesicles with receptors moves to the cell membrane
8.Transport vesicle and cell membrane fuse (membrane recycling).
9. Exocytoses
Specificity (Carrier-mediated transport competition) - Answers Will reduce concentration of original
molecule but it still lets the initial molecule to go through
Inhibitor (Carrier-mediated transport competition) - Answers Doesnt let the previous molecule in
Cell-to-Cell Communication: Four Basic Methods - Answers 1. Gap junctions
2. Contact-dependent signals
3. Local communication