NURS 5315 UTA Exam 2 Advanced
Pathophysiology Exam Latest 2026 Newest
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Terms in this set (106)
HIV EIA (3rd generation can use urine, saliva, or serum (most accurate),
immunoassay) need to wait until 12 weeks post exposure to see
antibodies, >99% accurate
4th generation immunoassay- "gold standard"
measures P24 antigen
can test 10 days post exposure
Mast cell Cellular bags of granules located in loose
connective tisssue close to blood vessels.
Activation initiates inflammatory process.
Histamine Causes vasodilation, increases vascular
permeability, increases blood flow to the site of
injury- causes erythema and swelling.
,Cytokines Soluble factors that contribute to the regulation
of innate or adaptive resistance by affecting
other neighboring cells. Can be pro-
inflammatory or anti-inflammatory. Can react
quickly or be more delayed.
Leukotrines Released when mast cells degranulate, prolong
the inflammatory process. Cause vasodilation,
attract neutrophils, monocytes, and
eosinophils.target of inhibition for singular.
Prostaglandins Released when mast cells degranulate, are
produced by the arachidonic pathway. Cause
vasodilation, platelet aggregation at site of injury,
pain, and fever.
Chemotactic factors Biochemical substance that attracts leukocyte to
the site of inflammation
Neutrophils Predominant leukocyte at work during the early
stages of acute inflammation
Monocytes Become macrophages when entering the tissue,
responsible for presenting antigens to the CD4
cell which triggers T-cell immunity and B-cell
immunity.
Releases additional cytokines IL1, IL6, TNF.
Cytokine IL1 function Causes fever, activates phagocytes &
lymphocytes and also increases the release of
IL6a
Cytokine IL6 function Stimulates production of acute phase reactants
and promotes growth and stimulation of RBCs
, Cytokine TNF function Causes fever, increases synthesis of
proinflammatory proteins by liver, causes muscle
wasting, induces thrombosis
Cytokine growth factor function Promotes production and maturation of
neutrophils
Complement Functions include bacterial lysis, vasodilation and
increased vascular permeability, triggers mast
cell degranulation, chemotaxis, and opsonization.
Kinin Converted to bradykinin which is responsible for
pain and chemotaxis, and it increases vascular
permeability and vasodilation.
Coagulation cascade Factor XII activates kinin. Function is to form fibrin
mesh to stop bleeding and trap micro organisms.
COX1 Prostaglandin of arachidonic pathway. Provides
gastroprotection, platelet aggregation,
fluid/electrolyte balance
COX2 Prostaglandin of arachidonic pathway.
Responsible for pain, fever, renal protection,
tissue repair, reproduction development.
Pathophysiology Exam Latest 2026 Newest
Questions and Answers (Latest
Update) (Verified Answers)
Save
Terms in this set (106)
HIV EIA (3rd generation can use urine, saliva, or serum (most accurate),
immunoassay) need to wait until 12 weeks post exposure to see
antibodies, >99% accurate
4th generation immunoassay- "gold standard"
measures P24 antigen
can test 10 days post exposure
Mast cell Cellular bags of granules located in loose
connective tisssue close to blood vessels.
Activation initiates inflammatory process.
Histamine Causes vasodilation, increases vascular
permeability, increases blood flow to the site of
injury- causes erythema and swelling.
,Cytokines Soluble factors that contribute to the regulation
of innate or adaptive resistance by affecting
other neighboring cells. Can be pro-
inflammatory or anti-inflammatory. Can react
quickly or be more delayed.
Leukotrines Released when mast cells degranulate, prolong
the inflammatory process. Cause vasodilation,
attract neutrophils, monocytes, and
eosinophils.target of inhibition for singular.
Prostaglandins Released when mast cells degranulate, are
produced by the arachidonic pathway. Cause
vasodilation, platelet aggregation at site of injury,
pain, and fever.
Chemotactic factors Biochemical substance that attracts leukocyte to
the site of inflammation
Neutrophils Predominant leukocyte at work during the early
stages of acute inflammation
Monocytes Become macrophages when entering the tissue,
responsible for presenting antigens to the CD4
cell which triggers T-cell immunity and B-cell
immunity.
Releases additional cytokines IL1, IL6, TNF.
Cytokine IL1 function Causes fever, activates phagocytes &
lymphocytes and also increases the release of
IL6a
Cytokine IL6 function Stimulates production of acute phase reactants
and promotes growth and stimulation of RBCs
, Cytokine TNF function Causes fever, increases synthesis of
proinflammatory proteins by liver, causes muscle
wasting, induces thrombosis
Cytokine growth factor function Promotes production and maturation of
neutrophils
Complement Functions include bacterial lysis, vasodilation and
increased vascular permeability, triggers mast
cell degranulation, chemotaxis, and opsonization.
Kinin Converted to bradykinin which is responsible for
pain and chemotaxis, and it increases vascular
permeability and vasodilation.
Coagulation cascade Factor XII activates kinin. Function is to form fibrin
mesh to stop bleeding and trap micro organisms.
COX1 Prostaglandin of arachidonic pathway. Provides
gastroprotection, platelet aggregation,
fluid/electrolyte balance
COX2 Prostaglandin of arachidonic pathway.
Responsible for pain, fever, renal protection,
tissue repair, reproduction development.
