Test Bank for Clayton’s Basic Pharmacology for Nurses 20th Edition By Willihnganz and Gurevitz

TestBank For Clayton’s Basic PharmacologyforNurses 19th Edition
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Chapter 01: Drug Definitions, Standards, and Information Sources Willihnganz:
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Clayton’sBasicPharmacology forNurses,19thEdition
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MULTIPLECHOICE v7




1. Whichnameidentifies adruglisted bythe US Food and v7 v7 v7 v7 v7 v7 v7 v7 v7 v7




Drug Administration (FDA)?
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a. Brand
b. Nonproprietary
c. Official
d. Trademark

ANS: C v 7




The official name is the name under which a drug is listed by the
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FDA. The brand name, or trademark, is the name given to a
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drug by its manufacturer. The nonproprietary, or generic, name
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is provided by the United States Adopted Names Council.
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DIF: CognitiveLevel: Knowledge REF: p. 9 v7 v7 v 7 v7




OBJ: 1NAT: NCLEX Client Needs Category: Safe, Effective Care v7 v7 v7 v7 v7 v7 v7 v7




Environment TOP: Nursing Process Step: Assessment
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Patient Education
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2. Whichsourcecontains information specific to nutritional supplements?
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a. USPDictionary of USAN &International Drug Names v7 v7 v7 v7 v7 v7 v7




b. NaturalMedicinesComprehensiveDatabase v7 v7 v7




c. UnitedStatesPharmacopoeia/NationalFormulary (USPNF) v7 v7 v7 v7 v7




d. DrugInteractionFacts v7 v7




ANS: C v 7




UnitedStatesPharmacopoeia/NationalFormularycontainsinformationspecificto nutritional
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supplements. USP Dictionary of USAN &International Drug Names is a compilation of drug
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names, pronunciation guide, and possible future FDA approved drugs; it does not include
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nutritional supplements. Natural Medicines Comprehensive Database contains
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evidence-based informationonherbalmedicines andherbal combinationproducts;itdoesnot v7 v7 v7 v7 v7 v7 v7 v7 v7 v7 v7




include information specific to nutritional supplements. Drug Interaction Facts contains
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comprehensive information on drug interaction facts; it does not include nutritional supplements.
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DIF: Cognitive Level: Knowledge REF: p. 4 OBJ:3 v7 v7 v 7 v7 v7




NAT: NCLEX Client Needs Category: Physiological Integrity
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TOP: NursingProcess Step: Assessment
v CON: Nutrition |Patient Education
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3. Whichdrugreference contains drugmonographs that describe all drugs ina therapeutic class?
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a. DrugFactsandComparisons v7 v7 v7




TestBank For Clayton’s Basic Pharmacology for Nurses 19th Edition v7 v7 v7 v7 v7 v7 v7 v7 v7

,TestBank For Clayton’s Basic PharmacologyforNurses 19th Edition
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b. DrugInteractionFacts v7 v7




c. Handbookon Injectable Drugs v7 v7 v7




d. Martindale—TheCompleteDrugReference v7 v7 v7




ANS: A v 7




Drug Facts and Comparisons contains drug monographs that describe all drugs in a
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therapeutic class. Monographsareformattedastablestoallowcomparison ofsimilar
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products, brand names, manufacturers, cost indices, and available dosage forms Online
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version is available.
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DIF: Cognitive Level: Knowledge REF: p. 4Table 1.2 v7 v7 v 7 v7 v7 v7




OBJ: 3 NAT: NCLEXClientNeedsCategory:PhysiologicalIntegrity
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TOP: NursingProcess Step: AssessmentvCON: Safety|Patient Education |Clinical Judgment
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4. Whichdrugreference contains monographs about virtuallyeverysingle-entitydrugavailable in
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the United States and describes therapeutic uses of drugs, including approved and unapproved
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uses?
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a. Martindale:TheCompleteDrugReference v7 v7 v7 v7




b. AHFSDrugInformation v7 v7




c. DrugReference v7




d. DrugFacts andComparisons v7 v7 v7




ANS: B v 7




AHFS Drug Information contains monographs about virtually every single-entity drug available
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intheUnitedStatesanddescribes therapeuticusesofdrugs, includingapproved and unapproved
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uses.
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DIF: Cognitive Level: Knowledge REF: p. 4Table 1.2 v7 v7 v 7 v7 v7 v7




OBJ: 3 NAT: NCLEXClientNeedsCategory:PhysiologicalIntegrity
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TOP: NursingProcess Step: Planning CON: Safety|Patient Education |Clinical Judgment
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5. Which online drug reference makes available to healthcare providers and the public a
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v7 standard,comprehensive, up-to-datelookupanddownloadableresourceaboutmedicines? v7 v7 v7 v7 v7 v7 v7 v7 v7




a. AmericanDrugIndex v7 v7




b. AmericanHospitalFormulary v7 v7




c. DailyMed
d. DrugReference v7




ANS: C v 7




DailyMed makes available tohealthcare providers and thepublic astandard,comprehensive, up- v7 v7 v7 v7 v7 v7 v7 v7 v7 v7 v7 v7




to-datelook upanddownloadableresource about medicines. TheAmericanDrug Indexis not
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appropriate for patient use. The American Hospital Formulary is not appropriate for patient use.
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The drug reference is not appropriate for patient use.
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DIF: Cognitive Level: Knowledge REF: p. 3 | p. 4 v7 v7 v 7 v7 v7 v7 v7 OBJ:3 v7




NAT: NCLEX Client Needs Category: Physiological Integrity
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TOP: NursingProcess Step: Implementation
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CON: Safety|Patient Education |ClinicalJudgment
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6. Whichlegislation authorizes theFDA to determinethesafetyof adrugbeforeits marketing?
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a. FederalFood, Drug, and CosmeticAct(1938) v7 v7 v7 v7 v7 v7




b. Durham HumphreyAmendment (1952) v7 v7 v7




TestBank For Clayton’s Basic Pharmacology for Nurses 19th Edition v7 v7 v7 v7 v7 v7 v7 v7 v7 v 7

,TestBank For Clayton’s Basic PharmacologyforNurses 19th Edition
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c. ControlledSubstancesAct(1970) v7 v7 v7




d. KefauverHarris DrugAmendment(1962) v7 v7 v7 v7




ANS: A v 7




The Federal Food, Drug, and Cosmetic Act of 1938 authorized the FDA to determine the safety of
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all drugs before marketing. Later amendments and acts helped tighten FDA control and ensure
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drug safety. The Durham Humphrey Amendment defines the kinds of drugs that cannot be used
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safely without medical supervision and restricts their sale to prescription by a licensed
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practitioner.The ControlledSubstances Actaddressesonlycontrolledsubstances and their
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categorization. The Kefauver Harris Drug Amendment ensures drug efficacyand greater drug
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safety. Drug manufacturers are required to prove to the FDA the effectiveness of their products
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before marketing them.
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DIF: Cognitive Level: Knowledge REF: p. 5Table l.3 v7 v7 v 7 v7 v7 v7




OBJ: v 7 5 NAT: NCLEX Client Needs Category: Physiological Integrity v7 v7 v7 v7 v7 v7




TOP:
v7 v Nursing Process Step: Assessment
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CON: v Safety|Patient Education|Evidence |Health Care Law
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7. Whichclassification doesmeperidine (Demerol)fall under?
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a. I
b. II
c. III
d. IV
ANS: B v 7




Meperidine (Demerol) is a Schedule II drug; it has a high potential for abuse and may lead to severe v7 v7 v7 v7 v7 v7 v7 v7 v7 v7 v7 v7 v7 v7 v7 v7 v7 v7




psychological and physical dependence. Schedule Idrugs havehigh potentialforabuse and no
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recognized medical use. Schedule III drugs have some potential for abuse. Use may lead to low to
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moderate physical dependence or high psychological dependence. Schedule IV drugs have low
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potential for abuse. Use may lead to limited physical or psychological dependence.
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DIF: Cognitive Level: Knowledge REF: p. 10 OBJ:2 v7 v7 v 7 v7 v7




NAT: NCLEX Client Needs Category: Safe, Effective Care Environment
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TOP: NursingProcess Step: Assessment
v CON: Patient Education |Addiction |Pain
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8. Whichaction would theFDAtaketo expeditedrugdevelopment and approval foran outbreak of
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smallpox?
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a. Listsmallpox asahealth orphandisease. v7 v7 v7 v7 v7 v7




b. Omitthepreclinical researchphase. v7 v7 v7 v7




c. Extendtheclinicalresearchphase. v7 v7 v7 v7




d. Fasttracktheinvestigational drug. v7 v7 v7 v7




ANS: D v 7




Once the Investigational New Drug Application has been approved, the drug can receive highest
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priority within the agency, which is called fast tracking. A smallpox outbreak would become a
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priority concern in the world. Orphan diseases are not researched in a priority manner. Preclinical
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research is not omitted. Extending any phase of the research would mean alongertimeto develop a
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vaccine.The FDAmust ensurethatall phasesof thepreclinical and clinical research phase have been
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completed in a safe manner.
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DIF: Cognitive Level: Knowledge v7 v7 REF: p. 7 v 7 v 7 v7 OBJ: v 7 5




TestBank For Clayton’s Basic Pharmacology for Nurses 19th Edition v7 v7 v7 v7 v7 v7 v7 v7 v7 v 7

, TestBank For Clayton’s Basic PharmacologyforNurses 19th Edition
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NAT: NCLEX Client Needs Category: Safe, Effective Care Environment
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TOP: Nursing Process Step: Assessment
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CON: Health CareLaw|Health Care Policy|Infection |Care Coordination
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9. Whichstatement is trueabout over-the-counter (OTC) drugs?
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a. Theyare not listed in theUSPNF. v7 v7 v7 v7 v7 v7 v7




b. A prescription froma healthcare provideris needed.
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c. Theyare sold without aprescription. v7 v7 v7 v7 v7




d. Theyare known onlybytheir brand names. v7 v7 v7 v7 v7 v7 v7




ANS: C v 7




OTC medications do not require a prescription. A variety of names, both generic and trade, canbe
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used forindividualdrugs sold OTC. OTC drugs are listed inthe USP NF. Prescription drugs require
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an order by a health professional who is licensed to prescribe, such as a physician, nurse
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practitioner, physician assistant, or dentist.
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DIF: Cognitive Level: Comprehension REF: p. 2 OBJ:2 v7 v7 v 7 v7 v7




NAT: NCLEX Client Needs Category: Physiological Integrity
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TOP: NursingProcess Step: Planning v CON: Patient Education
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10. Whichisthe most authoritative reference formedications thatare injected?
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a. Martindale:TheComplete v7 v7




b. Handbookon Injectable Drugs v7 v7 v7




c. DailyMed
d. Handbookof Nonprescription Drugs v7 v7 v7




ANS: B v 7




The Handbook on Injectable Drugs is the most comprehensive reference available on the topicof
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compatibilityof injectabledrugs. It isacollection ofmonographs for morethan 300 injectable drugs
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that are listed alphabetically by generic name.
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DIF: Cognitive Level: Knowledge REF: p. 4 OBJ:3 v7 v7 v 7 v7 v7




NAT: NCLEX Client Needs Category: Physiological Integrity
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TOP: NursingProcess Step: Assessment
v CON: ClinicalJudgment |Safety
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11. Whichstatement istrueabout Lomotil? v7 v7 v7 v7 v7




a. Abusepotential for this drugis low. v7 v7 v7 v7 v7 v7




b. Psychologicaldependencyislikely. v7 v7 v7




c. Thereis a high potential forabuse. v7 v7 v7 v7 v7 v7




d. This drugis not a controlled substance. v7 v7 v7 v7 v7 v7




ANS: A v 7




Lomotil, a Schedule V drug, has an abuse potential of limited physical or psychological
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dependenceliabilitycompared with drugs inSchedule IV. Because abusepotential islow with a
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Schedule Vdrug, a prescription maynot be required. Psychological dependencyis not likely with a
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Schedule V drug. Schedule V drugs are classified as controlled substances.
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DIF: Cognitive Level: Knowledge REF: p. 5 Box 1.1 OBJ:2 v7 v7 v 7 v7 v7 v7 v7




NAT: NCLEX Client Needs Category: Physiological Integrity
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TOP: NursingProcess Step: Assessment
v CON: ClinicalJudgment |Safety |Patient Education
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