NR 507 Midterm Exam questions (Latest Update 2026) UPDATE!! (Recent
exam) Fully solved & updated 2026 Most TESTED (2026
1. What antibodies primarily dri- IgE antibodies
ve Type I hypersensitivity reac-
tions?
2. Which cells become sensitized Mast cells and basophils
in Type I hypersensitivity?
3. What mediators are released Histamine, leukotrienes, prostaglandins, cytokines
upon allergen exposure in
Type I hypersensitivity?
4. What are the major clinical Vasodilation, bronchoconstriction, increased mucus produc-
manifestations of Type I hy- tion
persensitivity?
5. Is a Type I hypersensitivity re- Immediate
action immediate or delayed?
6. What characterizes Type II hy- Immune attack on cells displaying altered self‑antigens
persensitivity?
7. How are cells destroyed in Through complement activation or antibody‑dependent cell
Type II hypersensitivity? lysis
8. What determines symptoms in The tissue or organ where antigen is expressed
Type II hypersensitivity?
9. What precaution prevents Blood typing and cross‑matching
transfusion reactions?
10. What is formed in Type III hy- Antibody-antigen immune complexes
persensitivity?
, NR 507 Midterm Exam questions (Latest Update 2026) UPDATE!! (Recent
exam) Fully solved & updated 2026 Most TESTED (2026
11. Where do these complexes de- In vessel walls and tissues systemically
posit?
12. What immune component is The complement system
activated afterward?
13. What cells cause most tissue Neutrophils
injury?
14. Give examples of Type III dis- SLE, serum sickness, Raynaud phenomenon
orders.
15. What mediates Type IV hyper- T lymphocytes and macrophages
sensitivity?
16. When do Type IV reactions ap- 48-72 hours after exposure
pear?
17. What happens when T cells en- They migrate to the site and cause inflammation
counter antigen?
18. What is a granuloma? Cluster of immune cells that contain an antigen (Type IV reac-
tion)
19. Name autoimmune diseases Rheumatoid arthritis, type 1 diabetes
with Type IV reactions.
20. What type of virus is HIV? RNA retrovirus
21. What cells does HIV target? CD4+ T cells
22. How does HIV replicate? Reverse transcriptase converts RNA ’DNA ’enters host genome
23. What does ART therapy do? Suppresses viral replication and restores immune function
exam) Fully solved & updated 2026 Most TESTED (2026
1. What antibodies primarily dri- IgE antibodies
ve Type I hypersensitivity reac-
tions?
2. Which cells become sensitized Mast cells and basophils
in Type I hypersensitivity?
3. What mediators are released Histamine, leukotrienes, prostaglandins, cytokines
upon allergen exposure in
Type I hypersensitivity?
4. What are the major clinical Vasodilation, bronchoconstriction, increased mucus produc-
manifestations of Type I hy- tion
persensitivity?
5. Is a Type I hypersensitivity re- Immediate
action immediate or delayed?
6. What characterizes Type II hy- Immune attack on cells displaying altered self‑antigens
persensitivity?
7. How are cells destroyed in Through complement activation or antibody‑dependent cell
Type II hypersensitivity? lysis
8. What determines symptoms in The tissue or organ where antigen is expressed
Type II hypersensitivity?
9. What precaution prevents Blood typing and cross‑matching
transfusion reactions?
10. What is formed in Type III hy- Antibody-antigen immune complexes
persensitivity?
, NR 507 Midterm Exam questions (Latest Update 2026) UPDATE!! (Recent
exam) Fully solved & updated 2026 Most TESTED (2026
11. Where do these complexes de- In vessel walls and tissues systemically
posit?
12. What immune component is The complement system
activated afterward?
13. What cells cause most tissue Neutrophils
injury?
14. Give examples of Type III dis- SLE, serum sickness, Raynaud phenomenon
orders.
15. What mediates Type IV hyper- T lymphocytes and macrophages
sensitivity?
16. When do Type IV reactions ap- 48-72 hours after exposure
pear?
17. What happens when T cells en- They migrate to the site and cause inflammation
counter antigen?
18. What is a granuloma? Cluster of immune cells that contain an antigen (Type IV reac-
tion)
19. Name autoimmune diseases Rheumatoid arthritis, type 1 diabetes
with Type IV reactions.
20. What type of virus is HIV? RNA retrovirus
21. What cells does HIV target? CD4+ T cells
22. How does HIV replicate? Reverse transcriptase converts RNA ’DNA ’enters host genome
23. What does ART therapy do? Suppresses viral replication and restores immune function