CELLULAR AND MOLECULAR
IMMUNOLOGY 10TH EDITION TEST
BANK 2026 MEDICAL SCRIPT
SOLVED QUESTIONS VERIFIED
ANSWERS A+
◉ Balance between TH1 and TH2 cell activation determines outcome of
intracellular infections. Thus, in case of Mycobacterium leprae infection:
Answer: tuberculoid leprosy will occur in patients with a prominent TH1
response
◉ The initiation of T cell responses requires multiple receptors on the T
cells recognizing ligands on APCs. The MHC molecule located around
the peptide-binding cleft is recognized by the:
Answer: CD4 or CD8 molecules
◉ The edema occurring in the inflammatory process is the result of all
the following factors EXCEPT:
Answer: neural impulse by the sympathetic system and vasoconstriction
◉ Toll-Like Receptors (TLR):
Answer: recognize pathogen-associated molecular patterns (PAMPs) on
selective microorganisms
,◉ The initiation of T cell responses requires multiple receptors on the T
cells recognizing ligands on APCs. The T cell receptor transduction
molecule(s) is(are) conducted by:
Answer: CD3 and ζ molecules
◉ Which of the following is considered a primary lymphoid organ?
Answer: thymus
◉ Immediate activation of the B lymphocytes following contact with the
antigen involves all of the following molecules EXCEPT:
Answer: MHC class II molecules
◉ Immunologic memory refers to:
Answer: changes in adaptive immune responses with subsequent
encounters with antigen
◉ Both, naive mature effector T lymphocytes migrate differently in their
lives. Naive T cells express which adhesion molecule to mediate their
migration into lymph nodes through specialized vessels called high
endothelial venues (HEVs)?
Answer: L-selectin
◉ The main consequences of complement activation are all of the
following EXCEPT:
Answer: producing 2nd signal for macrophage activation
,◉ 'Langerhans Cells' which play a role in the immune system are:
Answer: dendritic cells located mainly in the epidermis
◉ All of the following cells results in the germinal center reaction of the
follicles (B lymphocyte zone) EXCEPT:
Answer: short-lived plasma cells
◉ The antigen recognition on the T cells is mediated by:
Answer: the Variable (v) regions of α and β chains
◉ The T-cell receptor:
Answer: recognizes antigen fragments via the α and β chains
◉ According to the clonal selection hypothesis, which of the following
is CORRECT?
Answer: Clones of lymphocytes specific for antigens develop prior to
exposure to the antigens
◉ Which of the following best describes the T-dependent antibody
response?
Answer: IT is the response of follicular B lymphocytes to a protein
antigen and characterized by isotope-switched, high affinity antibodies;
memory B cells, long lived plasma cells
, ◉ MHC class II molecules contain:
Answer: One α chain and one β chain
◉ The inflammatory cytokines will cause Langerhans cells in the
epidermis to perform all of the following EXCEPT:
Answer: antigen presentation to the T cells in the follicles of the lymph
nodes
◉ The phases and order of the specific or acquired immune responses
are:
Answer: recognition phase; activation phase; effector phase;
homeostasis phase; memory phase
◉ A naive CD4+ T cell may differentiate into subsets that produce
different cytokines that recruit and activate different cell types. The IFN-
γ is produced mainly by:
Answer: CD4+ T cell TH1 subset
◉ TH1 subset effector cells that aid in cell mediated immune response
activate the macrophage and B lymphocytes by:
Answer: CD40L-CD40 interaction and IFN-γ
◉ The diversity of antigen receptors produced by the use of different
combinations of V, D, and J gene segments in different clones of
lymphocytes is the result of:
Answer: both combinatorial diversity and junctional diversity
IMMUNOLOGY 10TH EDITION TEST
BANK 2026 MEDICAL SCRIPT
SOLVED QUESTIONS VERIFIED
ANSWERS A+
◉ Balance between TH1 and TH2 cell activation determines outcome of
intracellular infections. Thus, in case of Mycobacterium leprae infection:
Answer: tuberculoid leprosy will occur in patients with a prominent TH1
response
◉ The initiation of T cell responses requires multiple receptors on the T
cells recognizing ligands on APCs. The MHC molecule located around
the peptide-binding cleft is recognized by the:
Answer: CD4 or CD8 molecules
◉ The edema occurring in the inflammatory process is the result of all
the following factors EXCEPT:
Answer: neural impulse by the sympathetic system and vasoconstriction
◉ Toll-Like Receptors (TLR):
Answer: recognize pathogen-associated molecular patterns (PAMPs) on
selective microorganisms
,◉ The initiation of T cell responses requires multiple receptors on the T
cells recognizing ligands on APCs. The T cell receptor transduction
molecule(s) is(are) conducted by:
Answer: CD3 and ζ molecules
◉ Which of the following is considered a primary lymphoid organ?
Answer: thymus
◉ Immediate activation of the B lymphocytes following contact with the
antigen involves all of the following molecules EXCEPT:
Answer: MHC class II molecules
◉ Immunologic memory refers to:
Answer: changes in adaptive immune responses with subsequent
encounters with antigen
◉ Both, naive mature effector T lymphocytes migrate differently in their
lives. Naive T cells express which adhesion molecule to mediate their
migration into lymph nodes through specialized vessels called high
endothelial venues (HEVs)?
Answer: L-selectin
◉ The main consequences of complement activation are all of the
following EXCEPT:
Answer: producing 2nd signal for macrophage activation
,◉ 'Langerhans Cells' which play a role in the immune system are:
Answer: dendritic cells located mainly in the epidermis
◉ All of the following cells results in the germinal center reaction of the
follicles (B lymphocyte zone) EXCEPT:
Answer: short-lived plasma cells
◉ The antigen recognition on the T cells is mediated by:
Answer: the Variable (v) regions of α and β chains
◉ The T-cell receptor:
Answer: recognizes antigen fragments via the α and β chains
◉ According to the clonal selection hypothesis, which of the following
is CORRECT?
Answer: Clones of lymphocytes specific for antigens develop prior to
exposure to the antigens
◉ Which of the following best describes the T-dependent antibody
response?
Answer: IT is the response of follicular B lymphocytes to a protein
antigen and characterized by isotope-switched, high affinity antibodies;
memory B cells, long lived plasma cells
, ◉ MHC class II molecules contain:
Answer: One α chain and one β chain
◉ The inflammatory cytokines will cause Langerhans cells in the
epidermis to perform all of the following EXCEPT:
Answer: antigen presentation to the T cells in the follicles of the lymph
nodes
◉ The phases and order of the specific or acquired immune responses
are:
Answer: recognition phase; activation phase; effector phase;
homeostasis phase; memory phase
◉ A naive CD4+ T cell may differentiate into subsets that produce
different cytokines that recruit and activate different cell types. The IFN-
γ is produced mainly by:
Answer: CD4+ T cell TH1 subset
◉ TH1 subset effector cells that aid in cell mediated immune response
activate the macrophage and B lymphocytes by:
Answer: CD40L-CD40 interaction and IFN-γ
◉ The diversity of antigen receptors produced by the use of different
combinations of V, D, and J gene segments in different clones of
lymphocytes is the result of:
Answer: both combinatorial diversity and junctional diversity
