1–7 NCLEX REVIEW FOR NURSING
STUDENTS COMPLETE STUDY GUIDE 2026 |
PRACTICE QUESTIONS & ANSWERS
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Updated 2026 Questions and Answers
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,What factors affect drug Protein binding, free drug levels, and blood flow.
distribution?
What is the role of the liver in drug The liver metabolizes drugs, often through CYP450
metabolism? interactions.
What is the significance of renal Decreased renal clearance increases the risk of
clearance in older adults? drug toxicity.
What are agonists? Drugs that activate receptors to produce a
biological response.
What are antagonists? Drugs that block receptors and inhibit a biological
response.
What is the therapeutic index? The ratio between the toxic and therapeutic doses
of a drug.
What is the nursing process in Assessment, Diagnosis, Planning, Implementation,
pharmacology? Evaluation (ADPIE).
What is the priority assessment for Renal function (BUN/Cr).
older adults on multiple
medications?
, What is weight-based dosing in Dosing based on the child's weight to ensure safety
pediatrics? and efficacy.
What are high-alert medications? Drugs that have a higher risk of causing significant
harm if used incorrectly.
What is the significance of It helps prevent toxicity, especially for drugs with a
monitoring serum drug levels? narrow therapeutic index.
What is the main concern for a client The drug may accumulate and cause toxicity.
with liver cirrhosis prescribed a
metabolized drug?
What is the effect of sublingual It minimizes first-pass metabolism by bypassing the
administration on first-pass liver initially.
metabolism?
What is the most important lab value Albumin.
to review for a highly protein-bound
drug?
What is the priority nursing diagnosis Knowledge deficit related to medication regimen.
for a client who does not understand
their medication?
What is the best goal for teaching a Client will verbalize understanding of drug
client starting a new purpose and side effects before discharge.
antihypertensive?
What are the effects of potassium- They can cause hyperkalemia.
sparing diuretics?