UTMB 5355 ADVANCED PATHOPHYSIOLOGY
EXAM 3 MODULE 5 2026 COMPREHENSIVE
ASSESSMENT SCRIPT SOLVED QUESTIONS
ANSWERS UPDATED REVIEW SET
◉ Genotype.
Answer: genetic makeup of an organism
◉ locus.
Answer: Location of a gene on a chromosome
◉ Homozygous.
Answer: An organism that has two identical alleles for a trait
◉ Heterozygous.
Answer: An organism that has two different alleles for a trait
◉ Recessive.
Answer: trait of an organism that can be masked by the dominant
form of a trait
,◉ Dominant.
Answer: An allele that is always expressed
◉ Carrier.
Answer: A person whose genotype includes a gene with disease that
is not expressed in the phenotype.
◉ Expresstivity.
Answer: the degree to which a particular genotype is expressed in
the phenotype
◉ Spontaneous mutations are.
Answer: mutation that occurs within the body cells and NOT the
germline cells, caused by errors in DNA
◉ Mutagen.
Answer: chemical or physical agents in the environment that
increases frequency of mutations
◉ Radiation is an example of what:.
Answer: a mutagen
◉ Anticipation.
,Answer: signs and symptoms of genetic condition tend to become
more severe and appear at an earlier age as the disorder is passed
from generation to generation
◉ Huntington's disease is an example of.
Answer: A disease affected by anticipation
◉ reduced penetrance.
Answer: when a person inherits a dominant mutant gene but fails to
express it
◉ Penetrance.
Answer: The percentage of individuals with a specific genotype who
also express the expected phenotype
◉ 100% penetrance.
Answer: gene will always be expressed
◉ autosomal dominant means.
Answer: at least one parent is affected
◉ Clinical onset is later in life for.
Answer: autosomal dominant disorders
, ◉ Inheritance of Autosomal Dominant.
Answer: 50% chance
◉ autosomal recessive can be passed if.
Answer: two copies of an abnormal gene must be present in order
for the disease or trait to develop
◉ autosomal recessive disorders example.
Answer: Tay-Sachs, Cystic fibrosis, sickle cell anemia,
phenylketonuria
◉ Autosomal Recessive Inheritance.
Answer: Skips generations,
25% of offsprings from 2 carrier parents affected.
◉ Clinical onset earlier in life for:.
Answer: autosomal recessive
◉ What if a disorder exists in a offspring but parents are not
carriers?.
Answer: Spontaneous mutation
EXAM 3 MODULE 5 2026 COMPREHENSIVE
ASSESSMENT SCRIPT SOLVED QUESTIONS
ANSWERS UPDATED REVIEW SET
◉ Genotype.
Answer: genetic makeup of an organism
◉ locus.
Answer: Location of a gene on a chromosome
◉ Homozygous.
Answer: An organism that has two identical alleles for a trait
◉ Heterozygous.
Answer: An organism that has two different alleles for a trait
◉ Recessive.
Answer: trait of an organism that can be masked by the dominant
form of a trait
,◉ Dominant.
Answer: An allele that is always expressed
◉ Carrier.
Answer: A person whose genotype includes a gene with disease that
is not expressed in the phenotype.
◉ Expresstivity.
Answer: the degree to which a particular genotype is expressed in
the phenotype
◉ Spontaneous mutations are.
Answer: mutation that occurs within the body cells and NOT the
germline cells, caused by errors in DNA
◉ Mutagen.
Answer: chemical or physical agents in the environment that
increases frequency of mutations
◉ Radiation is an example of what:.
Answer: a mutagen
◉ Anticipation.
,Answer: signs and symptoms of genetic condition tend to become
more severe and appear at an earlier age as the disorder is passed
from generation to generation
◉ Huntington's disease is an example of.
Answer: A disease affected by anticipation
◉ reduced penetrance.
Answer: when a person inherits a dominant mutant gene but fails to
express it
◉ Penetrance.
Answer: The percentage of individuals with a specific genotype who
also express the expected phenotype
◉ 100% penetrance.
Answer: gene will always be expressed
◉ autosomal dominant means.
Answer: at least one parent is affected
◉ Clinical onset is later in life for.
Answer: autosomal dominant disorders
, ◉ Inheritance of Autosomal Dominant.
Answer: 50% chance
◉ autosomal recessive can be passed if.
Answer: two copies of an abnormal gene must be present in order
for the disease or trait to develop
◉ autosomal recessive disorders example.
Answer: Tay-Sachs, Cystic fibrosis, sickle cell anemia,
phenylketonuria
◉ Autosomal Recessive Inheritance.
Answer: Skips generations,
25% of offsprings from 2 carrier parents affected.
◉ Clinical onset earlier in life for:.
Answer: autosomal recessive
◉ What if a disorder exists in a offspring but parents are not
carriers?.
Answer: Spontaneous mutation
